Best TWAS P=2.4e-11 · Best GWAS P=4.21e-18 conditioned to 3.19e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RP11-848P1.7 | 0.54 | 0.00 | lasso | 10 | 0.02 | 7.3e-03 | -5.1 | -6.1 | 8.1e-10 | 0.47 | 0.02 | 0.06 | TRUE |
| 2 | GTEx | Brain Cerebellum | CRLF3 | 0.52 | 0.12 | lasso | 27 | 0.20 | 1.3e-06 | -7.8 | -6.7 | 2.4e-11 | 0.56 | 0.09 | 0.74 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GOSR1 | 0.02 | 0.01 | enet | 4 | 0.01 | 1.7e-02 | -5.1 | 5.1 | 3.0e-07 | -0.27 | 0.01 | 0.79 | FALSE |