[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted percentage :

chr11:61,627,881-63,110,149

Best TWAS P=4.87e-11 · Best GWAS P=9.01e-10 conditioned to 0.702

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ROM1 0.25 0.17 lasso 3 0.18 1.5e-14 6.1 -6.0 2.6e-09 -0.96 0.02 0.98 FALSE
2 GTEx Adipose Visceral Omentum ROM1 0.29 0.16 lasso 8 0.23 3.7e-12 5.7 -6.1 9.0e-10 -0.96 0.02 0.98 FALSE
3 GTEx Artery Aorta ROM1 0.18 0.17 lasso 7 0.16 3.3e-09 5.8 -5.9 2.7e-09 -0.97 0.02 0.98 FALSE
4 GTEx Artery Tibial ROM1 0.14 0.05 lasso 6 0.03 2.5e-03 6.1 -6.0 1.7e-09 -0.97 0.02 0.97 FALSE
5 GTEx Breast Mammary Tissue ROM1 0.10 0.09 lasso 5 0.06 5.4e-04 5.8 -5.8 5.3e-09 -0.97 0.03 0.96 FALSE
6 GTEx Breast Mammary Tissue (Female) ROM1 0.16 0.02 lasso 4 0.04 2.9e-02 5.7 -5.7 9.2e-09 -0.95 0.03 0.80 FALSE
7 GTEx Cells EBV-transformed lymphocytes EML3 0.33 0.22 lasso 8 0.21 1.6e-07 5.6 5.6 1.8e-08 0.95 0.02 0.97 FALSE
8 GTEx Cells Transformed fibroblasts EML3 0.19 0.16 lasso 9 0.18 7.3e-14 4.9 5.7 1.2e-08 0.95 0.04 0.96 FALSE
9 GTEx Esophagus Mucosa MTA2 0.29 0.34 lasso 5 0.33 6.9e-23 6.1 6.1 1.3e-09 0.98 0.02 0.98 FALSE
10 GTEx Esophagus Mucosa EML3 0.40 0.43 lasso 8 0.46 1.8e-33 5.8 6.0 2.6e-09 0.98 0.03 0.97 FALSE
11 GTEx Lung ROM1 0.25 0.18 enet 13 0.20 2.2e-15 6.1 -6.0 1.8e-09 -0.97 0.02 0.98 FALSE
12 GTEx Lung EML3 0.07 0.04 lasso 3 0.01 2.5e-02 6.1 6.1 1.4e-09 0.99 0.02 0.95 FALSE
13 GTEx Nerve Tibial EML3 0.17 0.10 lasso 4 0.09 3.9e-07 6.1 6.3 3.2e-10 0.97 0.01 0.99 FALSE
14 GTEx Ovary ROM1 0.25 0.00 lasso 5 0.00 3.3e-01 4.9 -5.8 8.9e-09 -0.94 0.03 0.73 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic ROM1 0.15 0.08 lasso 1 0.06 2.8e-04 5.3 -5.3 1.2e-07 -0.70 0.05 0.73 FALSE
16 GTEx Skin Not Sun Exposed Suprapubic EML3 0.20 0.19 lasso 3 0.24 2.7e-13 6.1 6.4 1.8e-10 0.97 0.01 0.99 FALSE
17 GTEx Skin Not Sun Exposed Suprapubic B3GAT3 0.18 0.11 lasso 3 0.11 9.8e-07 5.1 5.4 7.0e-08 0.80 0.53 0.46 FALSE
18 GTEx Skin Sun Exposed Lower leg MTA2 0.14 0.04 enet 21 0.05 3.1e-05 6.1 5.6 2.2e-08 0.79 0.02 0.97 FALSE
19 GTEx Skin Sun Exposed Lower leg ROM1 0.13 0.11 lasso 4 0.10 9.7e-09 6.1 -6.1 1.1e-09 -0.98 0.01 0.99 FALSE
20 GTEx Skin Sun Exposed Lower leg EML3 0.32 0.25 enet 19 0.26 8.0e-22 6.1 6.0 1.7e-09 0.96 0.01 0.99 FALSE
21 GTEx Spleen GANAB 0.35 -0.01 lasso 9 0.01 1.3e-01 6.1 6.2 5.8e-10 0.88 0.03 0.67 FALSE
22 GTEx Spleen MTA2 0.26 0.07 enet 19 0.07 8.7e-03 5.7 5.4 6.5e-08 0.81 0.03 0.85 FALSE
23 GTEx Stomach EML3 0.11 0.04 enet 5 0.03 2.1e-02 5.2 6.0 2.2e-09 0.97 0.02 0.84 FALSE
24 GTEx Testis EML3 0.27 0.22 enet 15 0.29 2.7e-13 6.1 5.9 2.8e-09 0.97 0.02 0.98 FALSE
25 GTEx Thyroid ROM1 0.17 0.16 lasso 8 0.16 3.6e-12 6.1 -6.1 8.7e-10 -0.99 0.02 0.98 FALSE
26 GTEx Thyroid EML3 0.10 0.11 lasso 4 0.10 5.9e-08 6.1 6.1 8.8e-10 1.00 0.01 0.99 FALSE
27 GTEx Whole Blood EML3 0.17 0.09 lasso 7 0.08 6.3e-08 5.8 5.8 6.3e-09 0.97 0.03 0.97 FALSE
28 METSIM Adipose EML3 0.15 0.14 bslmm 376 0.14 1.9e-20 5.8 5.1 2.7e-07 0.94 0.04 0.96 FALSE
29 YFS Blood EEF1G 0.30 0.45 lasso 6 0.45 3.6e-166 5.8 -5.8 7.2e-09 -0.97 0.06 0.94 FALSE
30 YFS Blood EML3 0.20 0.31 lasso 12 0.33 1.3e-110 6.0 6.2 7.1e-10 0.97 0.02 0.98 FALSE
31 YFS Blood INTS5 0.09 0.12 lasso 4 0.12 1.9e-38 5.1 5.6 2.6e-08 0.81 0.71 0.29 FALSE
32 The Cancer Genome Atlas Bladder Urothelial Carcinoma EEF1G 0.04 0.05 lasso 1 0.04 1.1e-04 6.1 -6.1 1.3e-09 -0.95 0.01 0.97 FALSE
33 The Cancer Genome Atlas Breast Invasive Carcinoma C11orf83 0.01 0.00 blup 23 0.01 4.2e-03 6.1 -5.2 1.7e-07 -0.75 0.01 0.71 FALSE
34 The Cancer Genome Atlas Breast Invasive Carcinoma EEF1G 0.02 0.04 lasso 2 0.03 6.3e-07 5.8 -5.8 6.2e-09 -0.97 0.02 0.98 FALSE
35 The Cancer Genome Atlas Breast Invasive Carcinoma EML3 0.02 0.02 lasso 4 0.02 2.5e-05 6.0 6.0 1.5e-09 0.97 0.02 0.98 FALSE
36 The Cancer Genome Atlas Breast Invasive Carcinoma ROM1 0.01 0.02 enet 4 0.02 2.4e-04 6.1 -5.9 3.2e-09 -0.93 0.01 0.96 FALSE
37 The Cancer Genome Atlas Colon Adenocarcinoma EEF1G 0.07 0.11 lasso 1 0.11 9.2e-07 5.6 -5.6 1.7e-08 -0.97 0.03 0.97 FALSE
38 The Cancer Genome Atlas Colon Adenocarcinoma EML3 0.07 0.03 blup 29 0.05 6.5e-04 4.9 5.6 2.5e-08 0.91 0.02 0.86 FALSE
39 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma EML3 0.06 0.05 blup 27 0.06 7.6e-07 6.0 5.6 1.8e-08 0.90 0.01 0.98 FALSE
40 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EEF1G 0.11 0.12 blup 27 0.13 5.5e-14 6.1 -6.1 8.9e-10 -0.95 0.02 0.98 FALSE
41 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EML3 0.04 0.06 lasso 3 0.06 1.7e-07 6.1 6.1 9.1e-10 1.00 0.02 0.98 FALSE
42 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EML3 0.06 0.09 lasso 2 0.08 1.6e-05 6.1 6.2 7.0e-10 0.87 0.01 0.98 FALSE
43 The Cancer Genome Atlas Brain Lower Grade Glioma C11orf83 0.02 0.01 blup 24 0.01 1.5e-02 6.1 -5.7 1.5e-08 -0.77 0.00 0.93 FALSE
44 The Cancer Genome Atlas Brain Lower Grade Glioma EEF1G 0.06 0.07 blup 27 0.07 8.1e-09 5.8 -6.4 1.6e-10 -0.94 0.02 0.98 FALSE
45 The Cancer Genome Atlas Brain Lower Grade Glioma EML3 0.03 0.04 blup 28 0.03 7.6e-05 6.0 6.2 5.0e-10 0.97 0.02 0.98 FALSE
46 The Cancer Genome Atlas Liver Hepatocellular Carcinoma EEF1G 0.06 0.03 blup 27 0.04 4.5e-03 6.1 -5.7 1.5e-08 -0.96 0.01 0.71 FALSE
47 The Cancer Genome Atlas Lung Adenocarcinoma EEF1G 0.06 0.08 lasso 8 0.08 5.9e-10 5.8 -5.6 2.1e-08 -0.95 0.02 0.98 FALSE
48 The Cancer Genome Atlas Lung Adenocarcinoma EML3 0.03 0.03 blup 28 0.03 8.4e-05 5.8 6.3 3.7e-10 0.97 0.02 0.98 FALSE
49 The Cancer Genome Atlas Lung Adenocarcinoma ROM1 0.04 0.04 blup 23 0.04 9.5e-06 5.8 -5.9 3.3e-09 -0.97 0.02 0.98 FALSE
50 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C11orf83 0.07 0.01 blup 24 0.01 1.0e-02 5.1 -5.1 2.8e-07 -0.72 0.01 0.81 FALSE
51 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EEF1G 0.08 0.13 lasso 4 0.12 3.1e-13 5.8 -5.8 6.5e-09 -0.97 0.02 0.98 FALSE
52 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EML3 0.04 0.05 blup 27 0.05 3.5e-06 6.1 5.8 8.4e-09 0.93 0.02 0.98 FALSE
53 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma EML3 0.03 0.02 blup 27 0.03 3.5e-03 6.1 6.1 1.2e-09 0.96 0.02 0.75 FALSE
54 The Cancer Genome Atlas Pancreatic Adenocarcinoma EEF1G 0.08 0.08 blup 27 0.05 3.6e-03 5.8 -6.0 1.5e-09 -0.96 0.02 0.94 FALSE
55 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EEF1G 0.08 0.00 blup 27 0.04 1.3e-02 5.8 -5.6 1.9e-08 -0.93 0.02 0.83 FALSE
56 The Cancer Genome Atlas Prostate Adenocarcinoma C11orf83 0.03 0.03 blup 24 0.02 5.5e-03 5.3 -5.3 1.3e-07 -0.76 0.03 0.90 FALSE
57 The Cancer Genome Atlas Prostate Adenocarcinoma EEF1G 0.08 0.13 lasso 2 0.12 1.8e-12 5.8 -5.8 6.4e-09 -0.97 0.03 0.97 FALSE
58 The Cancer Genome Atlas Prostate Adenocarcinoma EML3 0.09 0.14 lasso 1 0.14 3.4e-14 6.1 6.1 1.3e-09 0.95 0.02 0.98 FALSE
59 The Cancer Genome Atlas Rectum Adenocarcinoma EML3 0.36 0.08 blup 27 0.19 3.7e-05 6.0 5.2 1.7e-07 0.84 0.02 0.79 FALSE
60 The Cancer Genome Atlas Soft Tissue Sarcoma ROM1 0.06 0.05 blup 24 0.03 8.1e-03 5.8 -6.0 2.2e-09 -0.97 0.01 0.83 FALSE
61 The Cancer Genome Atlas Stomach Adenocarcinoma EEF1G 0.05 0.07 blup 27 0.07 1.7e-05 5.6 -6.1 1.2e-09 -0.97 0.02 0.98 FALSE
62 The Cancer Genome Atlas Stomach Adenocarcinoma ROM1 0.05 0.08 lasso 3 0.08 3.1e-06 6.1 -6.0 1.7e-09 -0.99 0.01 0.99 FALSE
63 The Cancer Genome Atlas Thyroid Carcinoma EEF1G 0.15 0.27 blup 27 0.28 3.6e-27 6.1 -6.2 7.2e-10 -0.92 0.01 0.99 FALSE
64 The Cancer Genome Atlas Thyroid Carcinoma EML3 0.11 0.10 blup 28 0.12 2.3e-11 6.1 6.6 4.9e-11 0.91 0.01 0.99 TRUE
65 The Cancer Genome Atlas Thyroid Carcinoma ROM1 0.03 0.02 blup 23 0.02 1.1e-02 6.1 -6.0 1.6e-09 -0.96 0.01 0.91 FALSE