Best TWAS P=1.37e-07 · Best GWAS P=9.44e-07 conditioned to 0.457
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | DUSP14 | 0.25 | 0.21 | lasso | 4 | 0.27 | 4.4e-19 | 4.7 | -5.3 | 1.4e-07 | -0.86 | 0 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SYNRG | 0.01 | 0.00 | blup | 57 | 0.00 | 1.2e-01 | 4.8 | 5.2 | 1.8e-07 | 0.69 | 0 | 0.42 | FALSE |