TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Pack years adult smoking proportion
:
→
chr3:48,381,826-49,817,450
Best TWAS P=4.29e-08 · Best GWAS P=8.04e-06 conditioned to 0.93
48.4M
48.6M
48.8M
49M
49.2M
49.4M
49.6M
49.8M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Pituitary
QRICH1
0.28
0.05
lasso
11
0.10
1.5e-03
4.3
5.5
4.3e-08
0.81
0.09
0.63
TRUE
2
GTEx
Spleen
QRICH1
0.24
0.21
enet
26
0.19
1.3e-05
4.3
5.2
2.2e-07
0.78
0.10
0.70
FALSE