Best TWAS P=4.29e-08 · Best GWAS P=8.04e-06 conditioned to 0.93
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Pituitary | QRICH1 | 0.28 | 0.05 | lasso | 11 | 0.10 | 1.5e-03 | 4.3 | 5.5 | 4.3e-08 | 0.81 | 0.09 | 0.63 | TRUE |
2 | GTEx | Spleen | QRICH1 | 0.24 | 0.21 | enet | 26 | 0.19 | 1.3e-05 | 4.3 | 5.2 | 2.2e-07 | 0.78 | 0.10 | 0.70 | FALSE |