Best TWAS P=1.81e-08 · Best GWAS P=1.13e-06 conditioned to 0.316
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CSE1L | 0.12 | 0.03 | lasso | 6 | 0.04 | 3.8e-04 | -4.4 | -5.2 | 1.7e-07 | -0.75 | 0.08 | 0.88 | FALSE |
| 2 | GTEx | Colon Transverse | ARFGEF2 | 0.11 | 0.07 | enet | 12 | 0.09 | 2.9e-05 | -4.3 | -5.2 | 2.1e-07 | -0.75 | 0.06 | 0.88 | FALSE |
| 3 | YFS | Blood | CSE1L | 0.06 | 0.05 | enet | 21 | 0.06 | 2.0e-19 | -4.3 | -5.6 | 1.8e-08 | -0.75 | 0.15 | 0.79 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CSE1L | 0.05 | 0.07 | blup | 50 | 0.07 | 3.2e-08 | 4.8 | -5.1 | 3.1e-07 | -0.97 | 0.01 | 0.98 | FALSE |