Best TWAS P=2.26e-08 · Best GWAS P=3.47e-07 conditioned to 0.0781
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | PCCB | 0.13 | 0.01 | enet | 5 | 0.04 | 6.4e-03 | -2.7 | -5.5 | 4.4e-08 | -0.62 | 0.01 | 0.30 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PCCB | 0.12 | 0.05 | enet | 7 | 0.09 | 9.7e-11 | -4.5 | -5.6 | 2.3e-08 | -0.68 | 0.02 | 0.97 | TRUE |
3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | STAG1 | 0.04 | 0.02 | lasso | 3 | 0.02 | 4.1e-03 | 4.9 | -5.1 | 3.1e-07 | -0.90 | 0.03 | 0.88 | FALSE |