[Hub]/) : Traits : Frequency of tiredness / lethargy in last 2 weeks :

chr9:95,502,571-96,898,436

Best TWAS P=6.78e-09 · Best GWAS P=1.35e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta RP11-165J3.6 0.23 0.22 enet 10 0.22 2.3e-12 5.5 5.4 7.4e-08 0.98 0.00 1.00 FALSE
2 GTEx Artery Tibial RP11-165J3.6 0.22 0.20 lasso 2 0.19 4.9e-15 5.5 5.5 3.2e-08 0.98 0.00 1.00 FALSE
3 GTEx Brain Caudate basal ganglia RP11-165J3.6 0.47 0.33 lasso 7 0.31 1.0e-09 5.5 5.2 1.6e-07 0.96 0.00 1.00 FALSE
4 GTEx Brain Cerebellum RP11-165J3.6 0.44 0.31 lasso 7 0.28 5.0e-09 5.5 5.4 6.1e-08 0.98 0.00 1.00 FALSE
5 GTEx Brain Frontal Cortex BA9 RP11-165J3.6 0.41 0.14 lasso 6 0.20 6.1e-06 5.5 5.3 9.9e-08 0.96 0.00 0.99 FALSE
6 GTEx Breast Mammary Tissue RP11-165J3.6 0.28 0.11 enet 24 0.13 2.7e-07 5.7 5.1 2.7e-07 0.89 0.00 1.00 FALSE
7 GTEx Breast Mammary Tissue (Female) RP11-165J3.6 0.21 0.02 lasso 3 0.00 2.3e-01 5.7 5.8 6.8e-09 0.99 0.01 0.87 TRUE
8 GTEx Colon Transverse RP11-165J3.6 0.37 0.20 lasso 4 0.18 3.6e-09 5.5 5.2 2.5e-07 0.96 0.00 1.00 FALSE
9 GTEx Esophagus Gastroesophageal Junction RP11-165J3.6 0.34 0.26 lasso 8 0.27 3.0e-10 5.5 5.6 2.4e-08 0.98 0.00 1.00 FALSE
10 GTEx Heart Atrial Appendage RP11-165J3.6 0.38 0.21 lasso 7 0.25 8.7e-12 5.3 5.3 1.3e-07 0.93 0.02 0.98 FALSE
11 GTEx Heart Left Ventricle RP11-165J3.6 0.13 0.06 lasso 5 0.05 1.9e-03 5.5 5.2 1.6e-07 0.94 0.01 0.98 FALSE
12 GTEx Lung RP11-165J3.6 0.25 0.16 lasso 7 0.17 4.1e-13 5.5 5.5 3.3e-08 0.97 0.00 1.00 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic RP11-165J3.6 0.27 0.14 lasso 7 0.19 1.4e-10 4.8 5.1 2.6e-07 0.93 0.02 0.98 FALSE
14 GTEx Skin Sun Exposed Lower leg RP11-165J3.6 0.32 0.27 lasso 5 0.35 6.8e-30 5.7 5.4 8.4e-08 0.96 0.00 1.00 FALSE
15 GTEx Thyroid RP11-165J3.6 0.35 0.27 lasso 3 0.29 1.2e-22 5.5 5.6 2.6e-08 0.98 0.00 0.99 FALSE