[Hub]/) : Traits : Seen doctor (GP) for nerves, anxiety, tension or depression : →

chr1:66,304,567-67,938,108

Best TWAS P=2.86e-12 · Best GWAS P=5.04e-09 conditioned to 0.48

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SGIP1 0.09 0.01 lasso 5 0.03 3.0e-03 -1.7 5.5 5.0e-08 0.74 0.08 0.80 FALSE
2 GTEx Adipose Visceral Omentum SGIP1 0.18 0.02 lasso 5 0.03 6.8e-03 5.6 5.5 5.0e-08 0.51 0.04 0.87 FALSE
3 GTEx Brain Cortex TCTEX1D1 0.27 0.23 lasso 7 0.26 8.7e-08 4.2 -5.7 1.4e-08 -0.59 0.48 0.27 FALSE
4 GTEx Brain Putamen basal ganglia TCTEX1D1 0.20 0.00 lasso 6 0.04 4.1e-02 -5.0 -5.9 4.0e-09 -0.72 0.11 0.43 FALSE
5 GTEx Colon Transverse SGIP1 0.19 0.01 enet 25 0.04 5.0e-03 1.4 5.2 2.7e-07 0.61 0.11 0.75 FALSE
6 GTEx Heart Left Ventricle SGIP1 0.24 0.26 lasso 7 0.28 3.1e-15 4.2 5.4 7.4e-08 0.68 0.34 0.65 FALSE
7 GTEx Muscle Skeletal SGIP1 0.07 0.04 enet 15 0.02 3.1e-03 5.6 5.9 3.8e-09 0.65 0.06 0.93 FALSE
8 GTEx Nerve Tibial SGIP1 0.18 0.06 lasso 3 0.07 1.4e-05 5.8 7.0 2.9e-12 0.88 0.02 0.98 TRUE
9 GTEx Vagina SGIP1 0.46 0.12 enet 10 0.07 1.4e-02 4.7 5.2 2.3e-07 0.76 0.07 0.50 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TCTEX1D1 0.04 0.03 lasso 1 0.02 2.4e-03 5.3 -5.3 1.5e-07 -0.56 0.00 0.96 FALSE