43 significantly associated models · 20 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 66304567 | 67938108 | 2 | 1 | 2.9e-12 | 5.0e-09 | 0.48000 | 98 | SGIP1 |
2 | 1 | 71163715 | 73435171 | 1 | 1 | 3.6e-11 | 6.8e-14 | 0.00015 | 74 | NEGR1 |
3 | 6 | 147140769 | 148587096 | 1 | 1 | 6.7e-08 | 2.1e-06 | 0.64300 | 99 | SAMD5 |
4 | 7 | 11553163 | 12967449 | 1 | 1 | 2.5e-10 | 2.4e-12 | 0.00161 | 80 | TMEM106B |
5 | 9 | 36590588 | 37277603 | 1 | 1 | 1.7e-07 | 8.9e-07 | 0.00962 | 72 | PAX5 |
6 | 9 | 125453469 | 127385609 | 1 | 1 | 2.0e-07 | 1.2e-06 | 0.00042 | 47 | DENND1A |
7 | 11 | 65670510 | 67070766 | 1 | 1 | 1.4e-07 | 1.7e-07 | 1.00000 | 100 | CCS |
8 | 11 | 89240503 | 90652993 | 1 | 1 | 8.9e-09 | 1.4e-07 | 0.00416 | 70 | CHORDC1 |
9 | 13 | 31078511 | 32595740 | 1 | 1 | 3.4e-08 | 7.8e-08 | 0.19200 | 94 | B3GALTL |
10 | 16 | 20915247 | 22360385 | 5 | 1 | 2.1e-09 | 1.3e-08 | 0.16100 | 94 | METTL9 |
11 | 18 | 52209411 | 54028036 | 1 | 1 | 4.5e-08 | 1.1e-09 | 0.00083 | 70 | TCF4 |
12 | 20 | 39720830 | 40229720 | 1 | 1 | 7.3e-09 | 7.6e-06 | 0.52600 | 98 | LPIN3 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.8 |
GTEx | Brain Cortex | 2 | 0.193 | 1.7 |
GTEx | Ovary | 0 | 0.000 | 1.7 |
GTEx | Vagina | 1 | 0.157 | 1.7 |
GTEx | Adipose Visceral Omentum | 1 | 0.049 | 1.6 |
GTEx | Artery Aorta | 1 | 0.034 | 1.6 |
GTEx | Artery Coronary | 0 | 0.000 | 1.6 |
GTEx | Artery Tibial | 0 | 0.000 | 1.6 |
GTEx | Brain Cerebellum | 0 | 0.000 | 1.6 |
GTEx | Brain Hippocampus | 1 | 0.191 | 1.6 |
GTEx | Breast Mammary Tissue | 0 | 0.000 | 1.6 |
GTEx | Breast Mammary Tissue (Female) | 0 | 0.000 | 1.6 |
GTEx | Cells EBV-transformed lymphocytes | 1 | 0.070 | 1.6 |
GTEx | Cells Transformed fibroblasts | 2 | 0.048 | 1.6 |
GTEx | Colon Sigmoid | 0 | 0.000 | 1.6 |
GTEx | Colon Transverse | 2 | 0.097 | 1.6 |
GTEx | Esophagus Gastroesophageal Junction | 0 | 0.000 | 1.6 |
GTEx | Esophagus Muscularis | 1 | 0.031 | 1.6 |
GTEx | Heart Atrial Appendage | 0 | 0.000 | 1.6 |
GTEx | Lung | 3 | 0.104 | 1.6 |
GTEx | Muscle Skeletal | 1 | 0.035 | 1.6 |
GTEx | Nerve Tibial | 1 | 0.023 | 1.6 |
GTEx | Pituitary | 0 | 0.000 | 1.6 |
GTEx | Skin Not Sun Exposed Suprapubic | 0 | 0.000 | 1.6 |
GTEx | Spleen | 0 | 0.000 | 1.6 |
GTEx | Stomach | 0 | 0.000 | 1.6 |
GTEx | Testis | 2 | 0.063 | 1.6 |
GTEx | Thyroid | 1 | 0.025 | 1.6 |
GTEx | Uterus | 0 | 0.000 | 1.6 |
NTR | Blood | 2 | 0.083 | 1.6 |
ROSMAP | Brain Pre-frontal Cortex | 2 | 0.046 | 1.6 |
CommonMind | Brain Pre-frontal Cortex | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 2 | 0.068 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 2 | 0.120 | 1.6 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 0 | 0.000 | 1.6 |
GTEx | Adipose Subcutaneous | 2 | 0.057 | 1.5 |
GTEx | Adrenal Gland | 0 | 0.000 | 1.5 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.5 |
GTEx | Brain Cerebellar Hemisphere | 0 | 0.000 | 1.5 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.5 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.5 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.5 |
GTEx | Brain Putamen basal ganglia | 1 | 0.160 | 1.5 |
GTEx | Esophagus Mucosa | 0 | 0.000 | 1.5 |
GTEx | Heart Left Ventricle | 1 | 0.065 | 1.5 |
GTEx | Pancreas | 0 | 0.000 | 1.5 |
GTEx | Prostate | 0 | 0.000 | 1.5 |
GTEx | Skin Sun Exposed Lower leg | 1 | 0.027 | 1.5 |
GTEx | Whole Blood | 1 | 0.050 | 1.5 |
METSIM | Adipose | 0 | 0.000 | 1.5 |
YFS | Blood | 1 | 0.022 | 1.5 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 2 | 0.121 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 1 | 0.023 | 1.5 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 1 | 0.024 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 2 | 0.080 | 1.5 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 1 | 0.022 | 1.5 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Thyroid Carcinoma | 1 | 0.019 | 1.5 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.5 |
GTEx | Breast Mammary Tissue (Male) | 0 | 0.000 | 1.4 |
GTEx | Liver | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 0 | 0.000 | 1.4 |