Bipolar Disorder (2018) |
1.51 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS |
Bipolar Disorder or Schizophrenia |
2.06 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS |
Depressed Affect (Nagel 2018) |
5.47 |
5 |
2 |
4.4 |
0.98 |
3.1e-03 |
B3GALTL PAX5 SAMD5 TCF4 TMEM106B |
Depression (Nagel 2018) |
4.53 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
TMEM106B |
Intelligence (Savage-Jansen 2018) |
3.77 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 |
Neuroticism (Nagel 2018) |
5.79 |
6 |
2 |
4.4 |
1.00 |
2.9e-05 |
B3GALTL CHORDC1 PAX5 SAMD5 TCF4 TMEM106B |
Schizophrenia (2018) |
1.74 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS PAX5 |
Schizophrenia vs Biploar Disorder |
2.11 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
PAX5 |
Worry (Nagel 2018) |
4.39 |
6 |
0 |
0.0 |
1.00 |
2.6e-05 |
B3GALTL DENND1A PAX5 SAMD5 TCF4 TMEM106B |
Alzheimer’s Disease (in mother) |
2.55 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
PAX5 |
Alzheimer’s Disease (including proxy) |
2.06 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
PAX5 |
Major Depression (MDD) |
6.96 |
3 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 TCF4 TMEM106B |
Verbal and Numeric Reasoning (VNR) |
3.28 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 |
Breast Cancer |
1.11 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Body Mass Index (BMI) (2010) |
4.78 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 |
LDL Cholesterol |
4.74 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
LPIN3 |
Neuroticism (2016) |
4.03 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
PAX5 TCF4 |
Schizophrenia (2014) |
1.57 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
PAX5 |
Blood Platelet Count |
0.63 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
LPIN3 SAMD5 |
Blood Red Count |
0.86 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
CCS LPIN3 |
Blood White Count |
0.56 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 SGIP1 |
Heel T-Score |
1.59 |
5 |
3 |
6.7 |
-0.55 |
3.4e-01 |
B3GALTL CCS LPIN3 NEGR1 TCF4 |
BMI |
3.71 |
5 |
2 |
4.4 |
0.91 |
2.9e-02 |
CCS CHORDC1 NEGR1 PAX5 TMEM106B |
Height |
0.84 |
3 |
3 |
6.7 |
0.00 |
1.0e+00 |
CCS TCF4 TMEM106B |
Waist Hip Ratio (WHR) |
1.12 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 |
Systolic Blood Pressure |
1.53 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
B3GALTL SGIP1 |
Allergy or Eczema |
1.63 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Cardiovascular Disease |
2.44 |
5 |
1 |
2.2 |
0.97 |
5.0e-03 |
CCS NEGR1 PAX5 SGIP1 TMEM106B |
Respiratory disease |
2.13 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS NEGR1 |
Type 2 Diabetes (T2D) (2018) |
1.94 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
PAX5 |
Lung FEV1/FVC ratio |
0.89 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 |
Lung FVC |
1.09 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
TCF4 |
Neuroticism |
5.95 |
5 |
2 |
4.4 |
0.98 |
2.7e-03 |
B3GALTL PAX5 SAMD5 TCF4 TMEM106B |
Chronotype (morning person) |
3.92 |
4 |
1 |
2.2 |
0.37 |
6.3e-01 |
DENND1A PAX5 SAMD5 TCF4 |
Hair Pigment |
0.16 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
DENND1A |
Tanning |
0.30 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 TCF4 |
Hand grip strength (left) |
2.33 |
2 |
2 |
4.4 |
0.00 |
1.0e+00 |
CCS TCF4 |
Number of treatments/medications taken |
4.59 |
4 |
0 |
0.0 |
0.98 |
1.7e-02 |
B3GALTL CCS NEGR1 SAMD5 |
Frequency of depressed mood in last 2 weeks |
5.56 |
3 |
0 |
0.0 |
0.00 |
1.0e+00 |
B3GALTL CHORDC1 TMEM106B |
Hearing difficulty/problems: Yes |
1.83 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS |
Relative age of first facial hair |
1.56 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Other serious medical condition/disability diagnosed by doctor |
2.96 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Systolic blood pressure, automated reading |
1.70 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
SGIP1 |
Vitamin and mineral supplements |
1.82 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Severe depression (siblings) |
3.82 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
SGIP1 |
Impedance of leg (right) |
1.74 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
CCS NEGR1 |
Leg fat-free mass (left) |
0.99 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Trunk fat percentage |
1.75 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Hand grip strength (right) |
2.01 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS TCF4 |
Current tobacco smoking |
0.98 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Fed-up feelings |
3.13 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
B3GALTL DENND1A |
Frequency of unenthusiasm / disinterest in last 2 weeks |
3.32 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
TMEM106B |
Taking other prescription medications |
5.04 |
5 |
0 |
0.0 |
0.99 |
1.8e-03 |
CCS NEGR1 SAMD5 TCF4 TMEM106B |
Age when periods started (menarche) |
2.65 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 |
High blood pressure |
2.18 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Hayfever, allergic rhinitis or eczema |
1.48 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Multivitamins +/- minerals |
1.77 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Stomach or abdominal pain in last month |
3.36 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 SGIP1 |
Sitting height |
0.42 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
TCF4 |
Body mass index (BMI) |
3.16 |
4 |
2 |
4.4 |
0.95 |
4.7e-02 |
CCS NEGR1 PAX5 TMEM106B |
Impedance of leg (left) |
1.68 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
CCS NEGR1 |
Leg predicted mass (left) |
0.97 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Trunk fat mass |
1.91 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Waist circumference |
2.70 |
4 |
1 |
2.2 |
0.97 |
3.3e-02 |
DENND1A LPIN3 NEGR1 PAX5 |
Alcohol usually taken with meals |
2.83 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 NEGR1 |
Nervous feelings |
3.67 |
4 |
0 |
0.0 |
-0.33 |
6.7e-01 |
B3GALTL METTL9 PAX5 TCF4 |
Frequency of tenseness / restlessness in last 2 weeks |
5.58 |
3 |
0 |
0.0 |
0.00 |
1.0e+00 |
B3GALTL TCF4 TMEM106B |
Hearing difficulty/problems with background noise |
2.67 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
DENND1A |
Hair/balding pattern: Pattern 2 |
1.41 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 |
Forced vital capacity (FVC) |
1.36 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
CCS |
Qualifications: None of the above |
2.49 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
B3GALTL NEGR1 |
Financial difficulties in last 2 years |
2.19 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
TMEM106B |
Allergy |
1.89 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS NEGR1 |
Pain all over the body in last month |
2.46 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
SAMD5 |
Medication: Simvastatin |
3.02 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
LPIN3 |
Fluid intelligence score |
2.48 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 |
Neuroticism score |
6.11 |
5 |
2 |
4.4 |
0.99 |
2.0e-03 |
B3GALTL PAX5 SAMD5 TCF4 TMEM106B |
Weight |
1.63 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Impedance of arm (right) |
1.32 |
3 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 SAMD5 TMEM106B |
Arm fat percentage (right) |
2.96 |
3 |
3 |
6.7 |
0.00 |
1.0e+00 |
CCS NEGR1 PAX5 |
Trunk fat-free mass |
0.52 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Hip circumference |
1.73 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Alcohol intake versus 10 years previously |
2.54 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 TMEM106B |
Worrier / anxious feelings |
4.63 |
4 |
1 |
2.2 |
0.97 |
2.8e-02 |
B3GALTL PAX5 TCF4 TMEM106B |
Frequency of tiredness / lethargy in last 2 weeks |
4.21 |
4 |
0 |
0.0 |
1.00 |
1.7e-03 |
B3GALTL CCS SAMD5 TMEM106B |
Hair/balding pattern: Pattern 3 |
2.40 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 METTL9 |
Forced expiratory volume in 1-second (FEV1) |
1.55 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
CCS |
Qualifications: A levels/AS levels or equivalent |
1.82 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 |
Mouth/teeth dental problems: Dentures |
1.63 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Asthma |
1.88 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS |
Medication: Cholesterol lowering |
1.56 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 |
Depression (self-reported) |
5.32 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
B3GALTL TMEM106B |
Forced expiratory volume in 1-second (FEV1), Best measure |
1.35 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS |
Impedance of arm (left) |
1.25 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 TMEM106B |
Arm fat mass (right) |
2.73 |
3 |
2 |
4.4 |
0.00 |
1.0e+00 |
CCS NEGR1 PAX5 |
Trunk predicted mass |
0.54 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Standing height |
0.85 |
3 |
1 |
2.2 |
0.00 |
1.0e+00 |
CCS TCF4 TMEM106B |
Tense / 'highly strung' |
5.05 |
4 |
2 |
4.4 |
0.96 |
3.9e-02 |
B3GALTL SAMD5 SGIP1 TMEM106B |
Hair/balding pattern: Pattern 4 |
1.80 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 METTL9 |
Peak expiratory flow (PEF) |
1.39 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS |
Headache pain in last month |
2.09 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 |
Medication for cholesterol, blood pressure or diabetes |
1.96 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Birth weight |
1.23 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS |
High blood pressure (siblings) |
2.09 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
TMEM106B |
Forced vital capacity (FVC), Best measure |
1.23 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
CCS |
Body fat percentage |
2.33 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Leg fat percentage (right) |
2.76 |
3 |
1 |
2.2 |
0.00 |
1.0e+00 |
LPIN3 NEGR1 PAX5 |
Arm fat-free mass (right) |
0.93 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 |
Comparative body size at age 10 |
4.22 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
B3GALTL NEGR1 |
Seen a psychiatrist for nerves, anxiety, tension or depression |
9.43 |
8 |
0 |
0.0 |
0.99 |
5.1e-07 |
DENND1A METTL9 NEGR1 PAX5 SAMD5 SGIP1 TCF4 TMEM106B |
Wheeze or whistling in the chest in last year |
2.43 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
DENND1A |
Health satisfaction |
2.64 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS |
Shortness of breath walking on level ground |
3.21 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS SGIP1 |
Qualifications: College or University degree |
3.75 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
B3GALTL NEGR1 |
Medication: Blood pressure |
1.25 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Angina (self-reported) |
1.95 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
TMEM106B |
Whole body fat mass |
2.37 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Leg fat mass (right) |
2.83 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Arm predicted mass (right) |
0.93 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 |
Pulse rate, automated reading |
2.11 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 SGIP1 |
Alcohol intake frequency. |
4.25 |
4 |
1 |
2.2 |
0.99 |
7.6e-03 |
LPIN3 NEGR1 SGIP1 TCF4 |
Comparative height size at age 10 |
1.14 |
3 |
1 |
2.2 |
0.00 |
1.0e+00 |
CCS TCF4 TMEM106B |
Suffer from 'nerves' |
2.52 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
B3GALTL TMEM106B |
Overall health rating |
3.70 |
4 |
0 |
0.0 |
0.98 |
1.8e-02 |
B3GALTL CCS SGIP1 TCF4 |
Chest pain or discomfort |
3.07 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
SAMD5 |
Commuting to job workplace: Car/motor vehicle |
1.83 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Medication: Aspirin |
1.78 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
TMEM106B |
Hypertension (Self-reported) |
2.07 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Whole body fat-free mass |
0.70 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Leg fat-free mass (right) |
0.86 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Arm fat percentage (left) |
3.00 |
3 |
3 |
6.7 |
0.00 |
1.0e+00 |
CCS NEGR1 PAX5 |
Average weekly red wine intake |
1.62 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Mood swings |
6.93 |
4 |
2 |
4.4 |
0.95 |
5.0e-02 |
B3GALTL PAX5 TCF4 TMEM106B |
Loneliness, isolation |
3.06 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
CHORDC1 TMEM106B |
Long-standing illness, disability or infirmity |
4.77 |
3 |
0 |
0.0 |
0.00 |
1.0e+00 |
DENND1A NEGR1 TMEM106B |
Diabetes diagnosed by doctor |
2.26 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
PAX5 |
Qualifications: nursing, teaching |
2.70 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
B3GALTL NEGR1 |
Asthma (self-reported) |
1.95 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
CCS |
Osteoporosis (self-reported) |
2.00 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
TCF4 |
Forced expiratory volume in 1-second (FEV1), predicted percentage |
1.02 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
DENND1A |
Whole body water mass |
0.71 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Leg predicted mass (right) |
0.86 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Arm fat mass (left) |
2.70 |
3 |
2 |
4.4 |
0.00 |
1.0e+00 |
CCS NEGR1 PAX5 |
Number of self-reported non-cancer illnesses |
6.28 |
4 |
1 |
2.2 |
0.80 |
2.0e-01 |
CCS DENND1A NEGR1 TMEM106B |
Miserableness |
6.03 |
4 |
2 |
4.4 |
0.99 |
8.8e-03 |
B3GALTL LPIN3 TCF4 TMEM106B |
Guilty feelings |
4.26 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 TCF4 |
Commuting to job workplace: Public transport |
1.91 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Medication: Blood pressure |
1.28 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
PAX5 |
High cholesterol (Self-reported) |
2.49 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
LPIN3 |
Basal metabolic rate |
0.90 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Leg fat percentage (left) |
2.70 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Arm fat-free mass (left) |
0.95 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Number of operations (self-reported) |
3.48 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 SAMD5 |
Average weekly beer plus cider intake |
1.34 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 |
Irritability |
4.98 |
4 |
1 |
2.2 |
1.00 |
7.1e-04 |
PAX5 SAMD5 TCF4 TMEM106B |
Diastolic blood pressure, automated reading |
1.52 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
LPIN3 PAX5 |
Ever depressed for a whole week |
3.48 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
TMEM106B |
Commuting to job workplace: Cycle |
2.82 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 TCF4 |
Vascular/heart problems diagnosed by doctor |
1.96 |
2 |
0 |
0.0 |
0.00 |
1.0e+00 |
NEGR1 TMEM106B |
Cholesterol lowering medication |
2.81 |
1 |
1 |
2.2 |
0.00 |
1.0e+00 |
LPIN3 |
Medication: Omeprazole (e.g. Zanprol) |
1.99 |
1 |
0 |
0.0 |
0.00 |
1.0e+00 |
SAMD5 |
Impedance of whole body |
1.43 |
3 |
1 |
2.2 |
0.00 |
1.0e+00 |
CCS NEGR1 TMEM106B |
Leg fat mass (left) |
2.84 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |
Arm predicted mass (left) |
0.96 |
2 |
1 |
2.2 |
0.00 |
1.0e+00 |
NEGR1 PAX5 |