[Hub]/) : Traits : Body mass index (BMI) : ← →

chr11:26,818,083-29,054,545

Best TWAS P=3.89e-25 · Best GWAS P=2.05e-39 conditioned to 5.48e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LIN7C 0.08 0.06 lasso 1 0.04 4.1e-04 10.36 10.4 3.9e-25 -0.26 0.86 0.00 TRUE
2 GTEx Brain Putamen basal ganglia BDNF-AS 0.22 0.17 lasso 4 0.13 5.5e-04 -7.63 8.8 8.5e-19 -0.65 0.05 0.81 FALSE
3 GTEx Cells Transformed fibroblasts LIN7C 0.26 0.22 lasso 6 0.25 1.4e-18 10.36 8.2 2.4e-16 -0.06 1.00 0.00 FALSE
4 GTEx Esophagus Muscularis LIN7C 0.14 0.08 enet 11 0.07 5.4e-05 2.52 6.6 3.2e-11 0.10 0.80 0.03 FALSE
5 GTEx Liver METTL15 0.18 0.05 lasso 3 0.09 1.9e-03 -2.02 -6.7 2.1e-11 0.27 0.09 0.11 FALSE
6 GTEx Nerve Tibial LIN7C 0.18 0.08 enet 27 0.12 4.2e-09 10.36 6.5 7.5e-11 -0.02 0.95 0.00 FALSE
7 GTEx Thyroid LIN7C 0.08 0.04 lasso 4 0.04 6.0e-04 10.36 9.8 1.5e-22 -0.14 0.81 0.01 FALSE
8 NTR Blood LIN7C 0.01 0.00 lasso 3 0.01 2.2e-03 10.61 -10.2 2.4e-24 0.17 0.52 0.02 FALSE
9 ROSMAP Brain Pre-frontal Cortex METTL15 0.04 0.03 blup 364 0.03 4.6e-05 -2.82 -5.8 7.4e-09 0.26 0.69 0.05 TRUE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma LIN7C 0.04 0.01 lasso 3 0.02 1.0e-02 -1.36 5.9 4.4e-09 0.07 0.02 0.83 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma LIN7C 0.10 0.03 blup 32 0.08 2.8e-05 10.57 7.2 7.8e-13 0.12 0.01 0.94 TRUE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LIN7C 0.05 0.02 lasso 3 0.03 2.9e-04 10.61 9.3 1.7e-20 -0.11 0.01 0.98 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma BDNFOS 0.03 0.01 blup 83 0.02 1.4e-03 0.57 6.8 1.2e-11 -0.76 0.01 0.96 TRUE