Best TWAS P=1.36e-14 · Best GWAS P=6.48e-20 conditioned to 0.00159
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | BTBD7 | 0.04 | 0.04 | lasso | 2 | 0.03 | 1.8e-04 | -6.0 | 6.3 | 2.5e-10 | -0.43 | 0.92 | 0.01 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | BTBD7 | 0.16 | 0.01 | lasso | 8 | 0.04 | 3.6e-04 | -7.4 | 7.2 | 7.2e-13 | -0.58 | 0.10 | 0.88 | FALSE |
| 3 | GTEx | Testis | BTBD7 | 0.19 | 0.00 | enet | 45 | 0.01 | 9.5e-02 | -5.8 | 6.0 | 1.6e-09 | -0.56 | 0.04 | 0.88 | FALSE |
| 4 | NTR | Blood | BTBD7 | 0.02 | 0.03 | lasso | 2 | 0.02 | 6.1e-08 | -6.0 | 6.6 | 4.9e-11 | -0.47 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C14orf142 | 0.11 | 0.04 | enet | 7 | 0.05 | 7.2e-07 | 3.8 | -5.4 | 5.4e-08 | 0.22 | 0.51 | 0.07 | TRUE |
| 6 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | BTBD7 | 0.02 | 0.01 | blup | 72 | 0.02 | 6.8e-03 | -8.3 | 7.7 | 1.4e-14 | -0.80 | 0.01 | 0.92 | TRUE |
| 7 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | BTBD7 | 0.11 | 0.03 | blup | 72 | 0.02 | 8.0e-02 | -7.4 | 7.0 | 2.1e-12 | -0.56 | 0.07 | 0.21 | FALSE |