[Hub]/) : Traits : Body mass index (BMI) : ← →

chr14:102,544,860-105,007,585

Best TWAS P=7.26e-13 · Best GWAS P=3.08e-16 conditioned to 9.28e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	MARK3	0.12	0.05	lasso	3	0.06	2.5e-05	-6.125	-5.3	9.6e-08	0.03	0.69	0.21	FALSE
2	GTEx	Adipose Subcutaneous	KLC1	0.05	0.03	lasso	3	0.03	1.8e-03	4.383	6.3	3.4e-10	-0.02	0.07	0.77	FALSE
3	GTEx	Adipose Subcutaneous	APOPT1	0.06	0.02	lasso	5	0.02	8.2e-03	5.282	-5.6	1.9e-08	0.03	0.22	0.48	FALSE
4	GTEx	Adipose Visceral Omentum	KLC1	0.06	0.02	lasso	2	0.00	2.2e-01	-6.166	6.4	1.3e-10	0.00	0.05	0.70	FALSE
5	GTEx	Adrenal Gland	KLC1	0.15	0.03	lasso	3	0.06	4.6e-03	5.260	6.5	6.7e-11	-0.03	0.09	0.45	FALSE
6	GTEx	Artery Aorta	KLC1	0.10	0.14	lasso	3	0.14	6.1e-08	-6.109	6.6	5.2e-11	0.00	0.04	0.96	FALSE
7	GTEx	Artery Coronary	APOPT1	0.19	0.02	lasso	5	0.05	1.2e-02	3.387	-5.6	2.0e-08	0.07	0.04	0.61	FALSE
8	GTEx	Artery Tibial	ZFYVE21	0.11	0.09	lasso	1	0.08	8.0e-07	-6.118	6.1	9.5e-10	0.00	0.03	0.97	FALSE
9	GTEx	Artery Tibial	KLC1	0.11	0.08	lasso	3	0.08	1.1e-06	-6.166	6.2	7.7e-10	-0.01	0.03	0.96	FALSE
10	GTEx	Artery Tibial	TRMT61A	0.07	0.07	lasso	3	0.06	2.4e-05	-6.144	-6.1	1.4e-09	0.03	0.04	0.95	FALSE
11	GTEx	Brain Frontal Cortex BA9	APOPT1	0.17	0.07	lasso	3	0.08	4.6e-03	4.926	-6.1	9.8e-10	0.02	0.05	0.72	FALSE
12	GTEx	Breast Mammary Tissue	MARK3	0.12	0.11	lasso	2	0.08	3.9e-05	-6.063	-6.1	1.3e-09	0.02	0.54	0.16	FALSE
13	GTEx	Breast Mammary Tissue	KLC1	0.12	0.02	enet	26	0.07	2.9e-04	4.314	6.3	3.0e-10	0.00	0.58	0.35	FALSE
14	GTEx	Breast Mammary Tissue (Male)	MARK3	0.08	0.00	enet	9	-0.01	7.2e-01	-6.070	-5.7	1.2e-08	0.04	0.04	0.10	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	PPP1R13B	0.15	0.08	lasso	4	0.07	2.2e-03	4.254	-5.1	2.7e-07	-0.04	0.41	0.06	FALSE
16	GTEx	Cells Transformed fibroblasts	ZFYVE21	0.10	0.03	lasso	4	0.11	1.1e-08	-5.085	5.4	8.6e-08	-0.03	0.08	0.86	FALSE
17	GTEx	Cells Transformed fibroblasts	KLC1	0.16	0.11	enet	17	0.10	3.1e-08	5.282	5.6	2.3e-08	-0.03	0.73	0.26	FALSE
18	GTEx	Cells Transformed fibroblasts	APOPT1	0.14	0.12	lasso	3	0.10	6.4e-08	-6.142	-6.5	9.4e-11	0.00	0.04	0.96	FALSE
19	GTEx	Colon Transverse	KLC1	0.16	0.01	lasso	7	0.00	1.9e-01	4.433	5.5	4.8e-08	-0.02	0.09	0.42	FALSE
20	GTEx	Esophagus Mucosa	XRCC3	0.12	0.15	lasso	2	0.13	4.4e-09	5.260	5.3	1.3e-07	-0.02	0.86	0.14	FALSE
21	GTEx	Esophagus Muscularis	ZFYVE21	0.11	0.06	lasso	5	0.05	5.7e-04	-6.050	5.6	1.8e-08	-0.04	0.02	0.96	FALSE
22	GTEx	Esophagus Muscularis	KLC1	0.07	0.01	enet	10	0.02	2.6e-02	-6.167	6.0	1.8e-09	-0.04	0.05	0.76	FALSE
23	GTEx	Lung	MARK3	0.06	0.02	lasso	3	0.01	6.6e-02	-6.063	-6.2	4.5e-10	0.02	0.35	0.24	FALSE
24	GTEx	Lung	CKB	0.07	0.01	lasso	2	0.01	3.4e-02	-6.166	-6.7	2.0e-11	0.01	0.04	0.90	FALSE
25	GTEx	Muscle Skeletal	ZFYVE21	0.10	0.05	lasso	2	0.03	3.3e-04	-6.142	6.2	6.8e-10	-0.02	0.04	0.94	FALSE
26	GTEx	Muscle Skeletal	KLC1	0.11	0.07	lasso	7	0.08	3.3e-08	-6.109	6.4	1.8e-10	-0.02	0.04	0.96	FALSE
27	GTEx	Muscle Skeletal	APOPT1	0.14	0.21	enet	10	0.22	6.7e-21	-6.050	6.7	2.3e-11	-0.02	0.01	0.99	FALSE
28	GTEx	Nerve Tibial	XRCC3	0.08	0.06	lasso	3	0.05	3.5e-04	5.282	5.2	2.3e-07	-0.05	0.79	0.16	FALSE
29	GTEx	Pituitary	MARK3	0.21	0.27	enet	8	0.25	4.9e-07	-6.070	-6.4	1.6e-10	0.02	0.50	0.18	FALSE
30	GTEx	Pituitary	RP11-73M18.8	0.23	0.17	lasso	2	0.13	3.6e-04	5.282	5.2	2.3e-07	-0.04	0.14	0.10	FALSE
31	GTEx	Prostate	MARK3	0.18	0.22	enet	11	0.20	8.0e-06	-6.069	-6.2	5.7e-10	0.03	0.43	0.15	FALSE
32	GTEx	Prostate	RP11-73M18.8	0.15	0.29	lasso	1	0.25	5.2e-07	5.260	5.3	1.4e-07	-0.02	0.38	0.14	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	MARK3	0.16	0.10	lasso	3	0.10	6.7e-06	-6.154	-5.7	1.4e-08	0.01	0.71	0.26	FALSE
34	GTEx	Skin Not Sun Exposed Suprapubic	XRCC3	0.14	0.03	lasso	14	0.03	1.3e-02	5.260	5.4	7.0e-08	-0.02	0.39	0.52	FALSE
35	GTEx	Skin Sun Exposed Lower leg	MARK3	0.10	0.09	enet	13	0.08	7.5e-07	-6.125	-6.5	7.2e-11	0.02	0.78	0.22	FALSE
36	GTEx	Skin Sun Exposed Lower leg	KLC1	0.06	0.09	enet	19	0.08	2.2e-07	5.282	5.7	1.4e-08	-0.02	0.18	0.82	FALSE
37	GTEx	Spleen	KLC1	0.15	0.05	lasso	3	0.03	6.4e-02	4.926	5.8	6.8e-09	-0.03	0.08	0.24	FALSE
38	GTEx	Stomach	MARK3	0.10	0.09	lasso	2	0.04	4.5e-03	-6.070	-6.1	9.2e-10	0.02	0.30	0.12	FALSE
39	GTEx	Stomach	TRMT61A	0.12	0.11	lasso	5	0.08	1.2e-04	-6.070	-6.1	1.2e-09	0.02	0.05	0.91	FALSE
40	GTEx	Testis	ZFYVE21	0.11	0.14	lasso	2	0.11	1.4e-05	-6.142	6.1	8.0e-10	0.00	0.04	0.94	FALSE
41	GTEx	Testis	KLC1	0.17	0.17	lasso	2	0.15	4.4e-07	5.260	5.2	2.5e-07	-0.02	0.78	0.12	FALSE
42	GTEx	Thyroid	MARK3	0.38	0.48	lasso	4	0.48	2.8e-41	-6.070	-6.1	1.2e-09	0.02	0.81	0.19	FALSE
43	GTEx	Thyroid	TRAF3	0.10	0.00	enet	20	0.05	1.4e-04	-0.021	6.1	1.0e-09	0.59	0.02	0.87	FALSE
44	GTEx	Whole Blood	KLC1	0.16	0.13	lasso	3	0.11	3.6e-10	5.260	5.1	2.8e-07	-0.03	0.85	0.15	FALSE
45	METSIM	Adipose	MARK3	0.03	0.02	lasso	6	0.03	6.3e-05	4.652	-5.9	4.1e-09	0.04	0.96	0.00	FALSE
46	METSIM	Adipose	TRAF3	0.04	0.02	enet	7	0.04	4.5e-06	6.818	6.9	6.6e-12	0.79	0.04	0.95	TRUE
47	NTR	Blood	BAG5	0.02	0.00	lasso	5	0.01	6.3e-03	-6.050	6.0	1.7e-09	-0.03	0.01	0.98	FALSE
48	YFS	Blood	KLC1	0.01	0.01	blup	389	0.01	1.0e-03	-6.026	6.0	1.9e-09	-0.03	0.03	0.93	FALSE
49	The Cancer Genome Atlas	Breast Invasive Carcinoma	C14orf153	0.05	0.02	lasso	4	0.02	8.0e-05	-6.050	-6.4	1.4e-10	0.03	0.00	0.99	FALSE
50	The Cancer Genome Atlas	Colon Adenocarcinoma	C14orf153	0.07	0.05	lasso	4	0.04	1.5e-03	-6.449	-6.0	1.5e-09	0.03	0.00	0.93	FALSE
51	The Cancer Genome Atlas	Glioblastoma Multiforme	C14orf153	0.14	0.01	blup	40	0.03	3.5e-02	-6.050	-6.8	1.2e-11	0.02	0.01	0.52	FALSE
52	The Cancer Genome Atlas	Glioblastoma Multiforme	MARK3	0.12	0.05	blup	64	0.07	3.3e-03	-6.154	-6.0	2.4e-09	0.01	0.01	0.62	FALSE
53	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MARK3	0.07	0.03	blup	64	0.06	5.5e-07	-4.471	-5.7	1.2e-08	0.03	0.04	0.96	FALSE
54	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	XRCC3	0.03	0.04	enet	3	0.04	6.1e-05	5.260	5.3	1.4e-07	-0.02	0.41	0.47	FALSE
55	The Cancer Genome Atlas	Brain Lower Grade Glioma	C14orf153	0.04	0.01	blup	38	0.03	6.2e-04	4.383	-6.6	4.0e-11	0.03	0.02	0.77	FALSE
56	The Cancer Genome Atlas	Lung Adenocarcinoma	C14orf153	0.06	0.02	blup	38	0.04	2.4e-05	-6.050	-7.0	2.3e-12	0.03	0.03	0.88	FALSE
57	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C14orf153	0.05	0.05	blup	40	0.04	8.6e-06	-6.442	-5.8	5.7e-09	0.03	0.00	1.00	FALSE
58	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CKB	0.03	0.00	blup	34	0.02	1.4e-03	4.652	-6.7	2.2e-11	0.03	0.02	0.72	FALSE
59	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	BAG5	0.08	0.09	lasso	2	0.08	3.7e-04	-6.070	-6.1	1.1e-09	0.02	0.01	0.88	FALSE
60	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C14orf153	0.11	0.11	lasso	3	0.10	1.1e-04	-6.449	-6.7	2.2e-11	0.03	0.00	0.98	FALSE
61	The Cancer Genome Atlas	Prostate Adenocarcinoma	C14orf153	0.09	0.08	blup	38	0.09	6.2e-10	-6.449	-7.2	7.3e-13	0.04	0.00	1.00	TRUE
62	The Cancer Genome Atlas	Prostate Adenocarcinoma	CKB	0.07	0.09	blup	32	0.10	1.1e-10	4.926	-6.0	2.6e-09	0.02	0.95	0.05	FALSE
63	The Cancer Genome Atlas	Prostate Adenocarcinoma	MARK3	0.07	0.06	enet	7	0.08	1.0e-08	-4.419	-5.5	4.4e-08	0.03	0.04	0.96	FALSE
64	The Cancer Genome Atlas	Stomach Adenocarcinoma	C14orf153	0.20	0.05	lasso	2	0.04	8.8e-04	4.926	-5.4	8.1e-08	0.02	0.03	0.34	FALSE
65	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C14orf153	0.20	0.07	blup	38	0.07	1.5e-03	2.883	-5.3	1.3e-07	0.00	0.01	0.60	FALSE
66	The Cancer Genome Atlas	Thyroid Carcinoma	KLC1	0.04	0.01	blup	82	0.03	5.4e-04	4.402	6.0	1.5e-09	-0.03	0.03	0.79	FALSE