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Traits
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Traits
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Body mass index (BMI)
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chr18:38,837,001-40,365,619
Best TWAS P=1.64e-09 · Best GWAS P=7.82e-11 conditioned to 1
38.8M
39M
39.2M
39.4M
39.6M
39.8M
40M
40.2M
40.4M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
The Cancer Genome Atlas
Colon Adenocarcinoma
PIK3C3
0.09
0.04
lasso
8
0.03
6.0e-03
6.4
-6.0
1.6e-09
-0.98
0.01
0.92
TRUE
2
GTEx
Testis
PIK3C3
0.10
0.01
enet
24
0.02
4.8e-02
5.3
-5.6
2.6e-08
-0.39
0.15
0.07
TRUE
1
GTEx
Nerve Tibial
PIK3C3
0.16
0.12
enet
13
0.15
1.2e-10
4.9
-6.0
2.5e-09
-0.60
0.91
0.09
FALSE
3
METSIM
Adipose
PIK3C3
0.10
0.08
enet
28
0.08
1.8e-12
5.6
-5.3
1.1e-07
-0.58
0.78
0.22
FALSE
4
YFS
Blood
PIK3C3
0.07
0.05
blup
418
0.05
4.4e-17
6.4
-5.3
1.3e-07
-0.85
0.01
0.99
FALSE