Best TWAS P=1.61e-07 · Best GWAS P=2.3e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | DYNC1I2 | 0.11 | 0.12 | lasso | 2 | 0.12 | 6.5e-12 | -5.1 | 5.1 | 2.8e-07 | -1.00 | 0.02 | 0.97 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | AC068039.4 | 0.43 | 0.64 | enet | 35 | 0.65 | 1.6e-110 | -5.0 | -5.2 | 1.6e-07 | 0.99 | 0.03 | 0.97 | TRUE |