TWAS
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About
Usage
Models
Genes
Traits
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Traits
:
Body mass index (BMI)
:
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chr2:174,238,261-175,812,508
Best TWAS P=1.07e-09 · Best GWAS P=6.41e-10 conditioned to 0.125
174.2M
174.4M
174.6M
174.8M
175M
175.2M
175.4M
175.6M
175.8M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
NTR
Blood
OLA1
0.04
0.02
enet
5
0.02
1.6e-07
5.5
6.1
1.1e-09
0.91
0.01
0.99
TRUE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
OLA1
0.06
0.05
lasso
3
0.06
8.6e-08
6.1
5.9
4.1e-09
0.96
0.00
1.00
FALSE
1
CommonMind
Brain Pre-frontal Cortex
OLA1
0.22
0.24
enet
22
0.25
2.8e-30
6.1
5.6
2.4e-08
0.94
0.00
1.00
FALSE