Best TWAS P=2.52e-07 · Best GWAS P=1.16e-07 conditioned to 9.73e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | RP5-1115A15.1 | 0.06 | 0.06 | lasso | 4 | 0.05 | 3e-04 | -4.9 | 5.2 | 2.7e-07 | -0.03 | 0.05 | 0.86 | FALSE |
2 | GTEx | Lung | RERE | 0.07 | 0.05 | lasso | 4 | 0.05 | 2e-04 | -5.1 | 5.2 | 2.5e-07 | -0.01 | 0.02 | 0.97 | TRUE |
3 | GTEx | Skin Not Sun Exposed Suprapubic | RP5-1115A15.1 | 0.08 | 0.04 | enet | 8 | 0.04 | 3e-03 | -5.1 | 5.2 | 2.6e-07 | -0.01 | 0.02 | 0.94 | FALSE |