TWAS
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Genes
Traits
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Traits
:
Body mass index (BMI)
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chr1:7,715,776-9,571,422
Best TWAS P=2.52e-07 · Best GWAS P=1.16e-07 conditioned to 9.73e-08
8M
8.5M
9M
9.5M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Lung
RERE
0.07
0.05
lasso
4
0.05
2e-04
-5.1
5.2
2.5e-07
-0.01
0.02
0.97
TRUE
3
GTEx
Skin Not Sun Exposed Suprapubic
RP5-1115A15.1
0.08
0.04
enet
8
0.04
3e-03
-5.1
5.2
2.6e-07
-0.01
0.02
0.94
FALSE
1
GTEx
Esophagus Mucosa
RP5-1115A15.1
0.06
0.06
lasso
4
0.05
3e-04
-4.9
5.2
2.7e-07
-0.03
0.05
0.86
FALSE