Best TWAS P=2.8e-14 · Best GWAS P=7.31e-20 conditioned to 1.49e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | 5.7 | 6.3 | 2.4e-10 | -0.23 | 1.00 | 0.00 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CADM2 | 0.06 | 0.00 | blup | 339 | 0.00 | 2.7e-01 | -5.8 | -7.6 | 2.8e-14 | 0.74 | 0.03 | 0.62 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | 6.7 | 7.5 | 5.5e-14 | -0.44 | 0.89 | 0.09 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | 6.7 | 7.6 | 3.6e-14 | -0.40 | 0.90 | 0.03 | FALSE |