TWAS
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Traits
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Traits
:
Body mass index (BMI)
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chr3:87,495,550-88,911,119
Best TWAS P=5.75e-09 · Best GWAS P=5.13e-10 conditioned to 4.31e-05
87.6M
87.8M
88M
88.2M
88.4M
88.6M
88.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Cells Transformed fibroblasts
ZNF654
0.08
0.09
enet
6
0.10
3.1e-08
-5.8
-5.8
5.8e-09
0.44
0.02
0.98
TRUE
1
CommonMind
Brain Pre-frontal Cortex
C3orf38
0.08
0.00
enet
14
0.04
2.3e-05
-5.0
-5.7
1.3e-08
0.32
0.15
0.73
FALSE
3
GTEx
Esophagus Mucosa
C3orf38
0.11
0.06
lasso
7
0.07
1.5e-05
-4.9
5.5
4.3e-08
-0.37
0.26
0.73
FALSE
4
GTEx
Testis
C3orf38
0.11
0.01
enet
12
0.00
1.9e-01
-5.4
5.3
1.1e-07
-0.76
0.07
0.51
FALSE