Best TWAS P=5.75e-09 · Best GWAS P=5.13e-10 conditioned to 4.31e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C3orf38 | 0.08 | 0.00 | enet | 14 | 0.04 | 2.3e-05 | -5.0 | -5.7 | 1.3e-08 | 0.32 | 0.15 | 0.73 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | ZNF654 | 0.08 | 0.09 | enet | 6 | 0.10 | 3.1e-08 | -5.8 | -5.8 | 5.8e-09 | 0.44 | 0.02 | 0.98 | TRUE |
| 3 | GTEx | Esophagus Mucosa | C3orf38 | 0.11 | 0.06 | lasso | 7 | 0.07 | 1.5e-05 | -4.9 | 5.5 | 4.3e-08 | -0.37 | 0.26 | 0.73 | FALSE |
| 4 | GTEx | Testis | C3orf38 | 0.11 | 0.01 | enet | 12 | 0.00 | 1.9e-01 | -5.4 | 5.3 | 1.1e-07 | -0.76 | 0.07 | 0.51 | FALSE |