Best TWAS P=2.96e-08 · Best GWAS P=2.67e-30 conditioned to 8.16e-25
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | SLC39A8 | 0.18 | 0.15 | lasso | 6 | 0.14 | 5.7e-20 | 5.5 | 5.5 | 3.0e-08 | 0.28 | 1.0 | 0.00 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SLC39A8 | 0.07 | 0.05 | lasso | 2 | 0.04 | 5.0e-05 | 5.5 | -5.2 | 2.6e-07 | -0.24 | 0.3 | 0.02 | FALSE |