Hub : Genes

SLC39A8

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1100 0.0310 3.4e-07 0.120 0.074 0.100 0.111 0.116 2.0e-14 2.4e-09 3.5e-12 2.1e-13 5.9e-14
2 GTEx Esophagus Mucosa 0.1500 0.0700 7.6e-03 -0.002 NA -0.004 NA -0.004 5.2e-01 NA 8.5e-01 NA 8.3e-01
3 GTEx Esophagus Muscularis 0.1100 0.0470 4.8e-03 0.012 NA 0.032 NA 0.023 5.6e-02 NA 4.7e-03 NA 1.5e-02
4 GTEx Lung 0.1055 0.0471 8.3e-03 -0.001 NA 0.000 NA 0.001 3.7e-01 NA 3.3e-01 NA 2.7e-01
5 GTEx Pituitary 0.2420 0.0880 6.7e-03 0.269 NA 0.166 NA 0.182 1.8e-07 NA 6.0e-05 NA 2.4e-05
6 METSIM Adipose 0.1750 0.0406 1.7e-11 0.146 0.087 0.127 0.137 0.137 3.6e-21 5.7e-13 2.0e-18 6.7e-20 5.7e-20
7 TCGA Breast Invasive Carcinoma 0.0877 0.0272 8.5e-11 0.059 0.057 0.058 NA 0.067 3.3e-12 8.6e-12 4.8e-12 NA 1.4e-13
8 TCGA Prostate Adenocarcinoma 0.0690 0.0369 7.0e-03 0.050 0.026 0.035 NA 0.040 5.8e-06 9.1e-04 1.3e-04 NA 5.0e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.2 0.3 0.7 -0.8 -0.1 0.1 -0.7 -0.3 -0.4 -0.8 0.4
Bipolar Disorder or Schizophrenia 0.8 1.9 5.5 0.0 -1.6 1.5 0.1 -0.2 2.4 0.0 -2.3
Depressed Affect (Nagel 2018) 0.6 1.2 3.2 -1.3 0.1 -0.0 0.5 -1.8 1.5 -1.0 -1.2
Depression (Nagel 2018) 1.2 1.9 5.7 0.9 0.4 1.8 2.4 -1.5 1.1 0.4 -1.3
Intelligence (Savage-Jansen 2018) 0.4 1.3 3.4 -0.2 0.8 0.3 -0.2 -1.4 -1.6 -1.8 1.2
Neuroticism (Nagel 2018) 0.4 1.0 2.5 -1.3 -0.6 0.0 0.0 -1.6 1.3 -0.7 -1.0
Schizophrenia (2018) 2.0 4.1 11.3 0.7 -2.2 1.9 1.0 -0.1 3.4 0.7 -3.3
Schizophrenia vs Biploar Disorder 1.3 1.7 6.0 0.2 -1.4 1.0 0.0 -0.3 2.4 0.3 -2.1
Worry (Nagel 2018) 0.2 0.4 1.2 -0.4 -0.4 1.1 0.4 -0.5 0.8 -0.1 -0.5
Alzheimer’s Disease (in mother) 1.4 1.6 4.4 0.3 0.1 -0.4 -0.8 1.7 -2.1 0.6 2.1
Alzheimer’s Disease (in father) 1.0 1.0 2.7 1.1 0.5 0.4 0.3 1.7 0.9 1.4 -0.9
Alzheimer’s Disease (including proxy) 0.5 0.7 3.5 0.6 0.4 -0.2 -0.1 1.9 -0.1 1.1 0.2
Crohns Disease (2017) 0.9 2.1 6.8 0.0 -1.2 1.6 -0.5 -0.4 2.6 0.5 -2.3
Irritable Bowel Disease (IBD) 0.6 1.5 3.6 0.9 1.6 1.9 0.5 0.7 1.4 1.0 -1.2
Ulcerative Colitis (UC) 1.3 2.5 7.9 1.6 2.8 1.4 1.4 1.8 0.2 1.4 -0.2
Major Depression (MDD) 0.5 0.6 1.8 0.3 0.7 -0.5 1.3 -0.5 1.0 0.1 -1.1
Reaction Time 0.8 1.4 2.6 1.1 1.6 0.4 -0.5 0.7 1.5 1.4 -1.6
Verbal and Numeric Reasoning (VNR) 0.7 1.7 6.1 0.3 0.7 -0.3 -1.2 0.3 -2.5 -0.7 2.2
Breast Cancer 0.6 1.4 7.0 1.0 2.6 0.6 1.2 0.1 -0.9 0.6 0.5
Ovarian Cancer 0.1 0.2 1.0 0.2 -0.2 -0.2 -1.0 0.5 -0.1 0.3 0.1
Prostate Cancer 1.4 2.0 5.0 -2.2 0.2 -1.0 -0.3 -0.8 -1.5 -2.1 1.8
Age at First Birth 1.5 2.2 6.2 -2.4 0.5 -0.3 0.6 -1.7 -0.9 -2.5 1.1
Bipolar Disorder (2011) 0.2 0.2 0.7 -0.5 0.5 0.1 0.0 -0.5 -0.1 -0.9 0.0
Body Mass Index (BMI) (2010) 0.9 1.2 2.8 -1.3 1.0 -0.6 -0.4 -1.3 1.7 -0.5 -1.4
Coronary Artery Disease (CAD) 1.0 1.2 5.2 -0.6 -0.7 -1.6 2.3 -0.3 0.4 -0.7 -0.3
Crohns Disease (2012) 0.8 1.3 5.7 -0.1 -2.4 0.1 0.0 -0.5 1.4 0.4 -1.3
Mean Putamen Volume 0.7 0.8 4.3 0.5 -0.5 2.1 0.7 -0.8 -0.6 -0.2 0.4
Fasting Glucose 0.5 0.6 2.5 -0.6 0.4 -1.6 -1.2 -0.1 0.0 0.0 0.1
HbA1C 0.2 0.3 0.8 -0.2 -0.2 -0.9 -0.7 0.4 0.0 -0.9 0.1
HDL Cholesterol 1.9 3.2 6.5 2.2 0.8 -1.0 0.6 2.1 -2.5 1.9 2.0
LDL Cholesterol 0.3 0.5 1.6 0.5 1.3 0.9 0.1 0.7 -0.6 0.3 0.4
Lupus 0.5 0.7 3.1 1.8 -0.5 0.5 0.7 0.6 0.1 1.1 -0.3
Neuroticism (2016) 1.1 1.6 4.1 -0.2 1.6 0.2 2.0 -1.4 1.6 -0.5 -1.3
Primary Biliary Cirrhosis 0.6 0.8 4.0 0.2 -1.3 0.7 2.0 -0.3 0.4 0.2 -0.4
Rheumatoid Arthritis 0.4 0.5 0.9 0.2 0.0 0.4 -0.7 1.0 -0.8 0.8 0.9
Schizophrenia (2014) 2.2 4.8 14.5 0.1 -1.3 2.6 1.2 -1.1 3.8 -0.0 -3.6
Triglycerides 0.7 1.1 2.2 -1.0 -0.8 1.2 -0.2 -1.5 1.2 -1.1 -1.1
Type 2 Diabetes (T2D) (2012) 1.4 1.6 2.4 -1.4 -0.4 -1.6 -1.4 -0.9 -1.2 -1.6 1.4
Ulcerative Colitis 1.2 1.7 4.4 1.8 1.7 2.1 0.5 0.8 0.5 1.2 -0.8
Blood Eosinophil Count 0.2 1.8 4.9 0.3 1.6 -0.8 -1.4 0.8 -2.2 -0.3 1.9
Blood Platelet Count 0.4 4.6 8.2 -2.7 1.3 -0.8 -2.3 -1.2 -2.7 -2.2 2.9
Blood Red Count 0.2 2.0 6.1 -0.2 1.9 0.3 -1.3 2.5 1.6 0.9 -0.8
Blood White Count 0.1 0.9 2.4 -1.1 0.3 -0.9 -1.5 0.3 1.2 0.4 -0.9
Heel T-Score 0.3 2.6 9.2 1.1 3.0 -0.4 -0.4 2.3 -1.3 1.3 1.3
BMI 1.3 7.8 19.1 -1.1 2.1 1.7 2.8 -2.6 4.4 -1.4 -4.2
Height 0.4 7.3 31.7 1.1 0.1 -0.1 0.8 0.8 -5.6 -0.2 4.9
Waist Hip Ratio (WHR) 0.9 4.0 7.3 2.3 -1.8 0.1 -1.9 2.7 -2.2 1.9 1.8
Systolic Blood Pressure 1.8 9.1 18.6 4.3 0.5 -0.9 -0.4 3.7 -4.1 3.7 3.1
Smoking Status 0.7 1.8 5.2 0.7 -1.2 -1.0 -0.4 1.3 -2.3 0.3 2.0
Allergy or Eczema 0.7 1.7 3.6 -1.1 -1.1 0.9 -0.6 -1.3 1.9 -1.5 -1.7
Cardiovascular Disease 1.0 3.3 8.7 2.7 -0.7 -1.7 -1.0 0.7 -2.9 1.6 1.9
Hypothyroidism (self reported) 3.3 7.7 17.0 4.1 2.8 0.3 -2.1 3.9 -0.7 4.1 0.1
Respiratory disease 0.4 0.9 2.9 -0.3 -0.9 -1.2 0.0 -0.3 1.7 -0.0 -1.5
Type 2 Diabetes (T2D) (2018) 0.9 1.6 3.3 -1.6 0.2 -1.2 -1.1 -1.2 1.8 -0.9 -1.5
Lung FEV1/FVC ratio 0.3 1.3 3.3 -1.2 0.1 -1.1 -1.8 1.3 -0.9 -0.8 1.3
Lung FVC 0.5 2.7 7.3 -0.7 -2.6 1.1 0.4 -0.5 2.7 0.2 -2.2
Neuroticism 0.6 1.4 3.8 -0.7 -0.9 0.9 0.3 -1.3 2.0 -0.7 -1.7
Chronotype (morning person) 0.8 1.8 6.7 -1.8 -1.3 -2.6 0.3 -0.9 -0.4 -1.0 0.7
Hair Pigment 0.1 1.6 3.6 -0.9 1.0 1.2 -0.3 -1.6 -1.4 -1.9 1.1
Tanning 0.1 0.8 3.2 0.3 -1.8 -0.2 -0.1 0.3 1.0 0.8 -1.0
Hand grip strength (left) 0.7 1.8 6.6 1.5 0.4 -0.1 -1.1 0.3 -2.6 0.2 1.9
Number of treatments/medications taken 1.7 3.1 7.8 0.9 1.4 -1.6 -1.2 -0.3 2.7 1.7 -2.8
Average weekly spirits intake 0.1 0.2 1.2 0.2 1.1 0.0 0.4 0.1 -0.0 0.1 -0.1
Sensitivity / hurt feelings 3.0 5.2 12.9 -1.0 -2.4 0.9 -0.1 -3.0 3.6 -0.5 -3.5
Frequency of depressed mood in last 2 weeks 0.5 0.6 2.2 0.5 -0.6 0.8 1.5 -0.8 0.6 0.2 -0.8
Hearing difficulty/problems: Yes 0.4 0.6 1.7 -1.3 -1.2 -0.7 -0.5 -0.3 -0.4 -0.8 0.8
Relative age of first facial hair 0.4 0.8 3.2 0.7 -1.5 1.8 0.5 0.4 0.3 -0.1 -0.2
Other serious medical condition/disability diagnosed by doctor 2.8 3.7 12.1 -0.0 0.2 -0.4 2.1 -1.5 3.5 0.1 -3.3
Ever used hormone-replacement therapy (HRT) 1.2 1.5 3.8 0.2 0.2 -1.5 0.3 1.1 1.9 1.3 -1.8
Ever had hysterectomy (womb removed) 0.4 0.4 0.9 0.2 0.0 -0.9 0.9 -0.1 0.8 0.4 -0.9
Systolic blood pressure, automated reading 1.0 2.9 7.7 2.2 1.1 -0.5 -1.3 2.8 -1.6 1.9 1.3
Eye problems/disorders: Diabetes related eye disease 0.4 0.5 1.5 -0.8 1.2 0.5 0.2 -0.8 0.3 -0.8 -0.2
Angina 0.7 1.0 4.1 0.2 -1.6 -2.0 0.4 -0.0 -0.7 0.2 0.7
Medication for hormone replacement therapy 0.3 0.3 2.2 0.2 0.1 -0.0 1.5 0.0 -0.2 -0.1 -0.0
Vitamin and mineral supplements 2.7 3.7 5.2 -2.0 1.2 -1.9 2.1 -2.3 -1.8 -2.0 1.8
Supplements: Zinc 0.5 0.5 1.0 -0.6 -1.0 -1.0 1.0 -0.4 0.7 -0.1 -0.5
Medication: Co-codamol 1.6 1.9 6.7 -0.9 0.3 -0.7 -0.1 -1.0 2.6 -0.6 -2.3
Medication: Metformin 2.8 3.9 10.2 -3.2 -1.1 -2.9 0.1 -2.2 0.4 -2.7 -0.0
Diabetes (father) 0.2 0.3 0.6 0.6 0.7 0.0 0.3 -0.3 0.8 0.7 -0.7
Diabetes (mother) 0.8 1.0 3.8 0.4 -2.0 1.0 -0.6 0.4 1.1 -0.2 -1.1
Severe depression (siblings) 0.4 0.4 1.1 -0.3 1.1 1.0 -0.6 -0.3 0.6 -0.2 -0.5
Pack years adult smoking proportion 0.5 0.7 1.5 -0.6 -0.7 -1.2 1.0 -1.0 -0.1 -1.2 0.0
Impedance of leg (right) 1.3 6.4 14.7 1.8 -0.3 -0.2 -2.1 3.4 -3.8 2.0 3.6
Leg fat-free mass (left) 0.8 4.2 9.4 -0.8 1.3 1.1 2.8 -3.1 1.9 -2.2 -2.1
Trunk fat percentage 1.3 5.1 16.8 -1.3 2.0 1.2 1.1 -1.2 4.1 -1.1 -3.7
Hand grip strength (right) 0.9 2.4 8.3 1.8 0.8 0.9 -1.2 0.5 -2.9 0.2 2.2
Townsend deprivation index at recruitment 0.7 1.0 2.4 1.5 -0.8 0.8 0.6 1.5 0.6 1.0 -0.5
Current tobacco smoking 0.9 1.5 4.6 0.1 -2.2 -1.4 -0.3 0.9 -1.6 0.1 1.4
Average weekly fortified wine intake 0.2 0.2 0.8 -0.6 0.3 0.1 -0.2 -0.4 0.4 -0.9 -0.3
Maternal smoking around birth 0.9 1.3 3.5 0.1 1.0 -1.1 1.9 -1.1 1.2 -0.3 -1.3
Fed-up feelings 0.2 0.5 1.7 -1.3 -0.6 -0.4 0.0 -0.8 0.5 -0.7 -0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 1.0 3.8 0.9 -0.9 -0.1 1.9 -0.2 0.8 0.8 -1.0
Relative age voice broke 0.9 1.3 6.2 -0.9 -2.5 -0.1 0.0 -1.1 0.2 -1.5 -0.1
Taking other prescription medications 2.6 4.0 12.9 1.0 0.9 -0.6 1.2 -0.6 3.6 1.4 -3.6
Age when periods started (menarche) 3.4 8.2 20.6 -4.4 -0.5 -1.3 0.4 -3.9 -2.0 -4.5 2.2
Bilateral oophorectomy (both ovaries removed) 0.8 0.9 2.4 0.3 -1.5 -1.1 1.0 0.7 0.3 1.2 -0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 4.0 -0.5 0.4 0.4 -1.1 0.5 -2.0 -0.6 1.8
Tinnitus: Yes, but not now, but have in the past 1.8 1.9 5.2 -1.9 1.1 0.1 1.3 -2.3 -0.2 -1.8 0.3
Qualifications: CSEs or equivalent 0.7 0.9 2.9 -1.7 0.6 -0.1 -0.2 -0.8 0.8 -1.7 -0.4
Serious illness, injury or assault to yourself 1.3 1.6 4.6 -1.0 -0.0 -0.7 -0.8 -1.2 2.1 -0.9 -1.9
High blood pressure 0.7 1.8 5.7 2.4 0.4 -1.8 -1.2 0.7 -0.6 1.8 -0.0
Hayfever, allergic rhinitis or eczema 0.5 1.1 3.3 -1.5 -1.3 0.8 -0.5 -0.9 -0.1 -1.8 0.3
Multivitamins +/- minerals 2.0 2.6 6.5 2.0 -1.3 2.1 -0.7 2.6 0.4 1.8 -0.5
Stomach or abdominal pain in last month 0.9 1.1 2.6 0.7 1.2 1.6 0.0 -0.4 1.4 0.4 -1.4
Supplements: Glucosamine 2.6 3.4 9.5 -3.1 1.2 -1.3 0.1 -2.8 0.6 -2.5 -0.2
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 1.9 0.9 0.9 0.2 -1.4 1.3 0.4 0.9 -0.5
Medication: Atenolol 0.8 1.0 4.0 2.0 -1.0 0.3 -0.5 -0.1 0.4 1.3 -1.0
Medication: Levothyroxine sodium 2.7 4.6 12.1 3.5 1.6 0.9 -1.1 2.5 0.9 3.3 -1.4
Sitting height 0.4 2.8 6.9 -1.6 -0.1 1.6 1.8 -2.6 1.5 -1.8 -1.4
Chronic bronchitis/emphysema (father) 0.1 0.2 0.6 0.3 0.4 0.8 0.2 0.7 0.1 -0.2 0.0
High blood pressure (mother) 1.1 1.5 3.7 1.9 -1.4 0.1 0.3 1.2 1.0 1.6 -1.1
Body mass index (BMI) 2.1 9.0 30.7 -0.9 2.1 0.9 2.0 -2.0 5.5 -1.1 -5.2
Impedance of leg (left) 1.6 7.7 18.2 1.3 -0.2 -0.4 -2.9 3.6 -4.3 1.9 4.1
Leg predicted mass (left) 0.8 4.2 9.1 -0.9 1.3 1.1 3.0 -3.0 1.8 -2.2 -2.0
Trunk fat mass 1.0 4.5 12.2 -1.0 2.2 1.1 1.6 -1.4 3.5 -1.3 -3.2
Waist circumference 0.9 3.3 11.6 -0.5 1.5 0.5 0.8 -0.9 3.4 -0.8 -3.2
Number of incorrect matches in round 0.8 1.4 4.7 0.5 2.2 -1.0 1.6 0.7 -0.1 1.4 -0.1
Past tobacco smoking 0.2 0.4 2.3 -0.1 -0.2 0.3 -0.6 1.5 0.4 0.4 -0.1
Alcohol usually taken with meals 0.5 0.7 2.8 -1.5 -0.5 -0.4 -1.7 -0.5 0.2 -0.5 0.1
Nervous feelings 0.2 0.4 0.9 -0.3 -0.4 0.4 0.9 -0.6 1.0 0.0 -0.8
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 2.7 1.0 -0.7 1.6 0.5 -0.3 1.2 0.7 -1.2
Hearing difficulty/problems with background noise 0.3 0.5 1.9 -0.8 0.0 0.6 1.4 -0.4 0.4 -0.9 -0.2
Hair/balding pattern: Pattern 2 0.8 1.0 2.5 0.5 1.3 0.2 1.1 0.1 1.6 0.7 -1.4
Had menopause 2.2 2.8 7.1 -0.4 1.7 -2.1 -0.8 0.7 2.7 0.9 -2.4
Had other major operations 1.1 1.4 2.3 1.5 -1.1 0.9 -0.1 1.2 1.4 1.3 -1.3
Forced vital capacity (FVC) 0.1 0.2 0.5 -0.4 -0.4 0.6 0.3 -0.7 -0.3 -0.6 0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.2 0.4 0.6 0.4 -0.4 1.1 -1.0 0.4 0.8
Ever unenthusiastic/disinterested for a whole week 1.3 1.6 4.5 -0.7 -1.7 0.5 0.9 -0.0 2.1 0.5 -1.9
Qualifications: None of the above 2.0 4.3 9.5 -1.1 -1.0 -2.7 2.5 -1.0 3.1 0.1 -2.8
Financial difficulties in last 2 years 2.2 3.0 8.1 -1.2 0.6 -0.4 1.2 -2.3 2.8 -1.1 -2.5
Mouth/teeth dental problems 0.4 0.7 1.6 0.2 0.1 1.0 0.2 1.3 -0.9 0.7 1.1
Heart attack 1.2 1.5 3.4 1.4 -0.9 1.1 0.7 0.2 1.7 1.2 -1.9
Allergy 0.4 1.0 3.6 1.0 1.9 -1.0 -0.3 0.6 -0.4 1.3 0.2
Pain all over the body in last month 1.1 1.1 3.4 -1.5 0.8 -0.2 1.0 -1.9 0.4 -1.1 -0.4
Diabetes (self-reported) 1.3 2.0 4.1 -2.0 -0.7 -2.0 -0.2 -1.6 1.1 -1.7 -0.9
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 2.8 -0.1 -1.1 0.2 -1.2 1.7 -0.3 0.1 0.5
Medication: Ramipril 1.4 1.8 4.9 1.1 -0.1 0.1 -2.2 -0.3 1.9 1.0 -2.0
Medication: Simvastatin 0.6 0.8 3.1 0.7 -0.9 -0.6 -1.8 0.8 -1.0 0.3 0.6
Fluid intelligence score 1.3 2.8 8.2 -0.7 -1.0 -0.7 -0.9 -0.9 -2.9 -1.7 2.7
Illnesses of siblings 0.7 1.0 5.1 -1.2 -0.4 0.4 -2.3 -0.5 -0.1 -0.8 0.2
Neuroticism score 0.6 1.2 2.8 -1.2 -0.5 0.3 0.6 -1.6 1.7 -0.8 -1.4
Weight 0.9 4.6 10.1 -0.8 2.0 0.8 2.3 -2.1 3.2 -1.6 -3.0
Impedance of arm (right) 0.2 1.1 2.8 0.1 -0.6 1.7 -1.2 0.6 -1.4 0.4 1.4
Arm fat percentage (right) 2.2 8.8 30.9 -1.0 1.8 1.3 1.8 -1.8 5.6 -0.9 -5.1
Trunk fat-free mass 0.2 1.4 4.4 0.1 1.4 0.1 2.1 -1.4 -0.9 -1.3 0.5
Hip circumference 1.3 5.7 11.4 -2.0 2.1 0.6 2.0 -2.7 3.4 -2.3 -3.0
Time employed in main current job 0.1 0.1 0.4 0.3 -0.5 0.7 -0.1 -0.1 0.0 0.6 -0.2
Alcohol intake versus 10 years previously 1.2 1.8 6.0 -1.1 1.1 0.1 0.3 -1.1 2.4 -0.9 -2.1
Father’s age at death 0.4 0.6 1.6 0.2 1.0 0.1 -1.1 1.3 -0.6 0.3 0.7
Worrier / anxious feelings 0.3 0.5 2.1 -1.4 0.2 0.2 0.2 -1.1 -0.1 -0.6 0.5
Frequency of tiredness / lethargy in last 2 weeks 1.9 3.2 6.5 -1.2 -0.8 -0.3 2.5 -2.5 2.3 -1.0 -2.1
Falls in the last year 0.4 0.5 2.2 0.2 1.5 -0.3 0.3 0.3 0.7 0.3 -0.8
Hair/balding pattern: Pattern 3 0.5 0.8 1.6 0.8 -0.4 -0.6 -1.2 0.6 -1.2 0.6 1.0
Number of live births 0.8 1.1 2.9 -1.4 -0.3 -1.7 0.2 -1.6 0.3 -1.2 -0.2
Forced expiratory volume in 1-second (FEV1) 0.1 0.3 0.9 -0.7 0.2 0.7 0.4 -0.8 0.0 -0.9 0.0
Pulse rate 1.7 2.8 6.5 -2.5 -1.1 -2.5 -0.1 -1.8 -0.6 -1.9 0.9
Happiness 0.6 0.7 2.0 0.3 0.3 -0.2 1.1 -0.3 1.3 0.5 -1.4
Noisy workplace 1.4 1.7 4.6 -2.1 -1.0 -1.0 1.0 -0.4 -1.0 -1.8 1.2
Qualifications: A levels/AS levels or equivalent 0.5 1.1 3.3 -0.7 0.9 -0.1 0.2 0.1 -1.7 -1.1 1.8
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 2.4 -0.8 1.1 0.2 0.2 -0.7 1.5 -0.1 -1.2
Mouth/teeth dental problems: Dentures 0.7 1.2 4.0 0.5 0.1 -0.7 -1.2 -0.2 1.8 0.5 -2.0
Asthma 0.4 0.8 2.7 -0.2 -0.9 0.2 0.7 0.1 1.7 -0.1 -1.5
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.4 0.2 -0.0 0.5 -0.2 -0.2 0.4 0.0 -0.6
Medication: Cholesterol lowering 0.5 0.8 4.0 0.5 -2.0 -1.1 -0.9 -0.2 -0.4 0.3 0.1
Depression (self-reported) 0.7 0.8 1.8 -1.1 -0.0 -0.6 1.2 -1.3 0.6 -1.1 -0.6
Medication: Lansoprazole 0.9 1.0 2.0 -1.2 -1.4 -0.7 -0.2 1.2 -1.0 -0.2 1.4
Prospective memory result 2.7 3.3 8.4 -1.8 0.5 -0.5 1.9 -1.7 2.9 -1.2 -2.6
Lung cancer (father) 2.8 3.3 7.9 1.1 1.9 1.0 1.9 -0.6 2.7 1.0 -2.8
Illnesses of mother 0.4 0.5 3.6 0.1 1.9 0.6 0.0 -0.1 -0.3 0.1 0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 0.7 -0.7 0.3 0.8 0.6 -0.4 0.1 -0.8 0.1
Pulse wave Arterial Stiffness index 0.1 0.1 0.4 -0.4 0.5 -0.1 0.7 -0.2 -0.2 -0.5 0.2
Impedance of arm (left) 0.4 1.7 3.3 0.2 -0.4 1.7 -1.5 1.2 -1.8 0.6 1.8
Arm fat mass (right) 1.7 7.0 19.4 -1.0 2.5 1.2 2.1 -2.0 4.4 -1.4 -4.2
Trunk predicted mass 0.2 1.4 4.3 0.0 1.4 0.0 2.1 -1.4 -0.9 -1.4 0.5
Standing height 0.6 5.8 24.8 0.1 0.2 0.1 0.8 -0.3 -5.0 -1.3 4.4
Length of working week for main job 0.3 0.4 1.1 -0.2 -0.6 0.4 -0.2 -0.3 -1.0 -0.6 0.9
Exposure to tobacco smoke at home 0.2 0.2 0.4 0.4 -0.6 0.4 -0.7 0.5 0.4 0.2 -0.4
Breastfed as a baby 0.9 1.1 3.2 0.9 -0.7 1.4 -1.8 1.1 -0.3 0.8 0.3
Tense / ‘highly strung’ 1.0 1.6 4.5 -0.5 -0.5 -0.0 2.1 -0.7 2.1 -0.0 -1.7
Seen doctor (GP) for nerves, anxiety, tension or depression 1.4 2.2 7.0 0.3 -0.8 0.6 1.2 -0.9 2.6 0.6 -2.6
Hair/balding pattern: Pattern 4 1.1 2.6 9.5 -0.6 -1.0 0.1 0.7 -0.1 -3.1 -1.3 2.8
Birth weight of first child 0.7 1.2 4.8 -0.2 -0.7 1.0 1.4 -2.2 -0.5 -1.1 0.2
Peak expiratory flow (PEF) 0.8 1.9 6.0 -1.9 -0.0 -0.5 0.9 -2.4 0.2 -2.2 -0.1
Pulse wave reflection index 0.2 0.2 0.7 0.5 -0.0 0.6 -0.3 0.8 -0.4 0.1 0.3
Ever highly irritable/argumentative for 2 days 0.2 0.3 1.1 -1.1 0.4 -0.3 0.0 0.5 -0.4 -0.2 0.6
Loud music exposure frequency 0.5 0.6 2.7 -0.6 -0.8 -0.7 -1.6 0.0 -0.1 -0.5 0.2
Qualifications: O levels/GCSEs or equivalent 0.6 1.0 5.5 0.8 0.1 2.3 -0.7 1.1 -0.3 0.1 0.2
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 2.8 -0.5 0.3 0.2 1.2 -1.7 -1.0 -1.0 1.0
Blood clot in the leg (DVT) 2.0 2.6 7.0 1.5 0.5 0.8 1.0 0.6 2.6 1.7 -2.6
Medication: Paracetamol 0.4 0.6 1.5 -0.6 0.2 -1.2 0.9 -0.7 1.0 -0.1 -0.9
Headache pain in last month 0.5 0.9 2.8 -1.2 0.3 -1.7 0.5 -0.5 1.1 -0.9 -0.8
Medication for cholesterol, blood pressure or diabetes 0.6 1.0 4.8 -0.5 0.6 2.2 1.3 0.3 0.1 -0.7 0.3
Glaucoma (self-reported) 0.4 0.5 2.0 0.6 1.4 0.7 0.5 0.5 -0.4 0.7 0.3
Gout (self-reported) 0.7 0.9 4.0 0.0 -0.9 -2.0 -0.9 1.0 -0.6 0.6 0.6
Hypothyroidism/myxoedema (self-reported) 3.3 6.5 18.2 4.1 1.2 0.2 -1.1 3.3 1.1 4.3 -1.6
Medication: Amlodipine 0.1 0.2 0.5 0.1 -0.0 -0.7 -0.6 -0.6 0.1 -0.1 -0.1
Medication: Ventolin 100micrograms inhaler 3.1 4.0 9.1 -2.3 -0.8 -2.0 1.8 -3.0 1.4 -2.6 -1.2
Birth weight 0.8 1.7 6.5 1.2 -0.5 2.5 1.9 -1.1 -0.2 -0.7 -0.3
Chronic bronchitis/emphysema (mother) 0.8 0.9 3.4 -0.9 -1.8 -1.2 -0.0 -0.6 0.4 -1.0 -0.3
High blood pressure (siblings) 1.9 2.7 7.1 2.7 -0.0 0.0 2.6 1.2 0.6 2.3 -0.8
Forced vital capacity (FVC), Best measure 0.1 0.4 0.8 -0.6 -0.2 0.9 0.7 -0.7 0.0 -0.9 0.1
Body fat percentage 1.4 5.6 20.2 -1.2 2.0 0.9 0.8 -0.9 4.5 -0.9 -4.0
Leg fat percentage (right) 1.3 4.8 19.1 -0.2 1.7 0.5 0.5 -0.2 4.4 0.1 -4.0
Arm fat-free mass (right) 0.3 1.7 5.5 -0.3 1.7 -0.2 2.3 -1.6 0.4 -1.4 -0.7
Exposure to tobacco smoke outside home 1.3 1.7 4.6 -2.1 0.4 -0.3 1.6 -1.2 0.1 -2.2 0.4
Comparative body size at age 10 0.8 2.1 7.2 0.3 1.1 1.3 -0.6 0.0 2.7 0.1 -2.5
Number of full brothers 0.5 0.6 1.8 0.4 0.4 0.5 1.1 -1.3 0.0 -1.1 -0.3
Worry too long after embarrassment 1.0 1.6 5.8 -1.1 -2.4 -0.2 -1.2 -0.3 -1.2 -1.0 1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 2.6 0.2 0.1 0.4 0.1 1.3 -1.6 -0.1 1.6
Wheeze or whistling in the chest in last year 0.2 0.3 0.8 -0.7 0.2 -0.9 0.9 -0.1 0.2 -0.5 -0.0
Number of children fathered 0.3 0.3 1.4 -0.4 0.2 -0.8 -1.2 -0.1 0.0 -0.3 0.1
Reason for reducing amount of alcohol drunk: Health precaution 2.4 2.8 5.9 2.4 -0.9 1.9 -0.5 1.6 1.2 2.3 -1.5
Age at first live birth 1.3 2.3 6.9 -1.7 0.5 1.0 -0.5 -1.8 -1.5 -2.6 1.4
Pulse wave peak to peak time 0.2 0.2 0.4 0.6 -0.5 0.3 -0.6 0.3 -0.0 0.6 -0.1
Health satisfaction 1.3 1.7 3.2 -1.8 -0.4 -1.5 1.7 -1.4 0.5 -1.7 -0.4
Shortness of breath walking on level ground 1.0 1.2 3.7 -1.0 0.6 -0.3 1.3 -1.3 0.6 -1.9 -0.6
Qualifications: College or University degree 0.7 2.2 6.9 0.8 -0.7 -0.2 -1.3 1.7 -2.6 0.7 2.2
Eye problems/disorders: None of the above 1.3 1.5 2.9 -1.3 -0.7 -0.9 -1.2 -0.6 -1.6 -1.3 1.7
Mouth/teeth dental problems: Loose teeth 0.0 0.0 0.2 -0.1 -0.1 0.2 -0.1 0.2 -0.1 -0.5 0.2
Emphysema/chronic bronchitis 1.0 1.1 3.2 -1.6 0.4 -1.8 -0.6 -1.2 -0.3 -1.1 0.4
Medication for pain relief, constipation, heartburn 1.2 2.0 6.2 -0.5 -0.2 1.4 -0.4 0.1 -2.4 -1.2 2.5
Neck or shoulder pain in last month 1.5 2.2 5.0 -2.2 0.1 -0.0 1.9 -2.1 1.1 -1.7 -0.7
Medication: Blood pressure 0.5 1.0 4.5 0.8 0.7 -2.1 -0.8 -0.6 0.3 0.8 -0.8
Angina (self-reported) 0.6 0.8 2.9 0.4 -1.3 -1.7 0.3 0.1 -0.8 0.3 0.7
Migraine (self-reported) 0.5 0.6 1.5 -0.9 -0.8 -0.5 -0.2 -0.2 -1.2 -0.5 1.1
Medication: Ibuprofen 0.6 0.7 1.8 0.8 0.7 0.8 -0.6 0.1 1.2 0.7 -1.4
Medication: Allopurinol 1.8 2.3 5.3 0.0 -0.1 -1.6 -1.2 2.1 -2.3 0.0 2.2
Medication: Omeprazole 2.4 2.8 5.3 2.2 -0.4 0.9 1.0 0.8 2.1 2.3 -2.2
Medication: Seretide 50 evohaler 0.5 0.6 2.6 0.5 -1.6 0.5 -0.3 0.6 0.7 0.4 -0.8
Mean time to correctly identify matches 1.1 2.0 4.3 1.0 1.1 0.2 -0.9 1.2 2.1 1.8 -2.0
Heart disease (mother) 1.1 1.4 2.6 -1.6 -0.2 -1.3 1.4 -1.6 0.6 -1.4 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.9 2.0 0.6 0.8 -0.3 -1.4 0.6 -1.1 1.1 1.1
Whole body fat mass 1.1 4.6 13.8 -1.1 2.0 0.9 1.3 -1.4 3.7 -1.3 -3.4
Leg fat mass (right) 1.3 5.1 16.6 -0.4 1.8 0.9 1.5 -1.4 4.1 -0.8 -3.9
Arm predicted mass (right) 0.3 1.6 4.8 -0.1 1.9 0.0 2.2 -1.5 0.4 -1.3 -0.7
Pulse rate, automated reading 0.4 1.2 3.2 -1.0 1.3 -1.8 -1.5 0.4 -0.7 -0.3 1.0
Alcohol intake frequency. 1.7 4.0 12.9 -1.1 1.3 0.2 1.1 -1.9 3.6 -0.8 -3.2
Comparative height size at age 10 0.4 2.2 6.8 1.0 0.5 -1.2 0.1 1.5 -2.6 0.8 2.3
Number of full sisters 1.0 1.2 6.1 -0.3 -0.6 1.0 2.5 -1.1 0.4 -0.6 -0.3
Suffer from ‘nerves’ 0.5 0.8 2.1 -0.1 -0.7 1.5 0.7 -0.0 1.4 0.2 -1.2
Overall health rating 0.7 1.6 4.2 -1.1 -0.4 -0.7 2.0 -1.4 1.6 -0.8 -1.3
Chest pain or discomfort 0.3 0.4 2.2 -0.5 -1.5 -0.7 -0.1 -0.2 -0.0 -0.4 0.1
Had major operations 0.1 0.1 0.4 0.4 -0.1 0.0 -0.1 0.4 -0.1 0.7 -0.1
Age at last live birth 2.7 3.9 11.6 -2.3 0.9 1.0 1.6 -2.9 -0.8 -3.4 0.9
Family relationship satisfaction 0.4 0.5 1.1 -0.0 0.5 0.4 0.9 0.8 -0.9 -0.2 1.0
Leg pain on walking 3.1 3.9 8.9 -2.4 -0.6 -0.6 3.0 -2.5 1.6 -2.3 -1.2
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.4 1.8 -0.4 -0.3 1.3 -0.8 -0.7 0.5 -0.3 -0.2
Commuting to job workplace: Car/motor vehicle 1.5 1.7 3.5 -1.5 -1.2 0.1 -0.4 -1.9 1.2 -1.8 -1.2
Illness, injury, bereavement, stress in last 2 years 2.1 2.6 4.9 1.2 -2.0 0.4 -1.4 2.0 -2.2 1.0 1.8
Medication: Aspirin 1.3 1.8 5.3 0.8 -1.1 -1.0 0.6 -0.4 2.2 0.7 -2.3
Supplements: Vitamin C 1.0 1.1 4.8 -0.5 -0.6 -0.3 -0.5 0.0 2.2 -0.4 -1.9
Knee pain experienced in last month 1.7 2.6 7.1 -1.7 1.0 1.0 2.7 -2.0 0.5 -2.0 -0.3
Hypertension (Self-reported) 0.6 1.7 4.9 2.2 0.5 -1.9 -1.1 0.5 -0.5 1.7 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.1 2.4 1.4 0.5 1.5 -0.3 1.1 0.7 1.4 -0.6
Illnesses of father: Heart disease 1.1 1.5 5.5 -2.3 0.4 -0.1 0.7 -1.1 0.4 -2.1 -0.0
Illnesses of siblings: Diabetes 0.6 0.7 1.7 -0.7 0.4 -1.2 -0.5 -1.3 0.7 -0.9 -0.4
Smoking status: Previous 0.3 0.4 2.3 0.1 0.5 0.3 0.3 -1.5 0.4 -0.0 -0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.9 5.8 1.2 0.9 1.6 0.0 0.6 -2.4 0.0 2.0
Whole body fat-free mass 0.4 2.1 6.1 -0.4 1.5 0.4 2.5 -2.1 0.2 -1.8 -0.5
Leg fat-free mass (right) 0.7 3.9 9.7 -1.2 1.4 1.0 2.5 -3.1 1.4 -2.5 -1.6
Arm fat percentage (left) 2.1 8.4 29.4 -1.0 1.8 1.4 1.6 -1.7 5.4 -0.9 -5.0
Average weekly red wine intake 1.1 1.6 5.2 -0.7 -0.1 -0.8 -1.1 0.3 -2.3 -0.5 2.3
Handedness (chirality/laterality): Left-handed 0.7 0.8 2.9 0.9 -1.1 0.1 -0.4 0.9 0.6 1.7 -0.4
Mood swings 0.9 1.6 4.2 -0.1 1.1 -0.8 1.5 -0.5 2.0 0.7 -1.8
Loneliness, isolation 0.9 1.2 2.2 -0.6 0.8 -0.4 1.2 -1.5 1.4 -1.0 -1.3
Long-standing illness, disability or infirmity 1.6 2.5 5.5 -0.3 -1.0 0.3 1.6 -2.4 2.3 -0.7 -2.2
Ever had bowel cancer screening 1.8 2.1 4.6 -2.1 0.9 -1.8 -1.9 -0.6 -0.3 -1.7 0.8
Diabetes diagnosed by doctor 1.6 2.6 5.6 -2.4 -1.0 -2.3 0.0 -1.8 1.4 -1.6 -1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 1.7 1.3 -0.7 0.6 0.8 0.7 0.2 1.0 -0.3
Friendships satisfaction 1.9 2.4 7.4 1.2 2.7 2.7 -0.1 1.5 -0.3 0.7 0.4
Qualifications: nursing, teaching 0.7 1.1 3.1 1.3 -1.0 1.7 -1.1 0.9 -0.5 0.8 0.4
Commuting to job workplace: Walk 1.1 1.2 2.7 0.9 0.2 0.2 -1.2 1.6 -1.2 1.2 1.3
Eye problems/disorders: Cataract 0.9 1.0 2.5 1.1 -0.1 0.3 -0.2 1.0 1.2 1.6 -1.2
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 2.3 0.7 0.2 0.2 -1.5 0.9 -0.0 0.4 -0.2
Medication for cholesterol 1.1 1.7 4.9 -2.2 -0.0 1.2 0.2 -1.7 0.2 -2.0 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.9 1.4 -1.2 -0.0 -0.7 1.2 -0.8 1.0 -1.0 -0.9
Back pain experienced in last month 2.5 3.6 7.6 -1.4 -2.6 0.8 2.8 -2.5 1.5 -1.1 -1.4
Mineral and other dietary supplements 0.8 1.0 2.5 1.1 -0.3 1.6 0.9 0.2 -1.5 -0.0 1.1
Breast cancer (self-reported) 0.5 0.6 1.4 0.8 0.9 0.2 -0.8 1.2 -0.2 1.0 0.1
Asthma (self-reported) 0.5 1.1 4.0 -0.3 -0.9 0.0 0.7 -0.0 2.0 -0.2 -1.8
Osteoporosis (self-reported) 0.7 0.9 3.9 0.6 -0.8 0.4 2.0 -0.1 0.9 0.7 -1.0
Osteoarthritis (self-reported) 2.0 2.6 6.8 -2.6 0.3 -0.9 0.1 -2.4 1.6 -1.9 -1.1
Medication: Aspirin 1.5 1.9 5.7 0.6 -0.8 -1.4 0.8 -0.6 2.3 0.6 -2.4
Medication: Gliclazide 0.4 0.4 1.1 -1.1 -0.9 -0.7 -0.0 -0.1 -0.0 -0.9 0.3
Illnesses of father: None of the above (group 1) 0.3 0.4 1.2 0.6 -0.9 0.5 -1.1 -0.4 0.2 0.1 -0.3
Smoking status: Current 1.2 1.9 4.7 -0.1 -2.2 -1.5 -0.2 1.1 -1.9 -0.2 1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.0 2.1 6.9 0.6 -0.6 1.3 0.3 0.5 2.6 1.3 -2.4
Whole body water mass 0.4 2.3 6.5 -0.4 1.5 0.5 2.5 -2.3 0.3 -1.9 -0.6
Leg predicted mass (right) 0.7 3.8 9.3 -1.2 1.5 1.1 2.5 -3.0 1.3 -2.5 -1.5
Arm fat mass (left) 1.5 6.2 18.2 -0.8 2.1 1.3 1.8 -1.8 4.3 -1.2 -4.1
Number of self-reported non-cancer illnesses 1.8 3.1 8.9 1.6 -0.7 -0.5 -1.0 -0.2 2.8 1.8 -3.0
Average weekly champagne plus white wine intake 0.4 0.6 1.5 0.5 0.5 -1.2 -0.7 -0.0 -1.2 0.5 0.8
Miserableness 0.4 0.6 1.8 -0.9 -1.0 0.6 0.2 -1.4 0.3 -0.9 -0.2
Guilty feelings 0.5 0.8 3.7 -1.2 -0.2 -1.9 -0.2 -0.4 0.2 -0.8 -0.1
Wears glasses or contact lenses 1.0 1.2 2.2 -1.5 1.1 -1.5 0.0 -1.2 0.7 -1.2 -0.6
Ever taken oral contraceptive pill 0.8 0.9 2.1 -0.8 1.4 -1.3 -1.0 -1.1 -0.1 -0.8 0.2
Hearing aid user 1.1 1.2 3.4 0.9 -0.8 -0.9 -1.0 1.2 1.0 1.8 -0.8
Mother’s age at death 0.7 0.8 2.4 -0.3 -1.5 0.1 0.3 0.2 -1.4 -0.4 1.4
Financial situation satisfaction 0.3 0.4 1.1 0.4 -0.3 1.1 0.7 0.9 -0.4 0.6 0.3
Tinnitus: Yes, now most or all of the time 0.2 0.2 0.7 -0.4 0.4 0.9 -0.2 0.8 -0.2 0.2 0.5
Commuting to job workplace: Public transport 0.2 0.2 0.6 0.8 -0.0 0.0 0.5 0.3 -0.6 0.7 0.4
Eye problems/disorders: Glaucoma 0.9 1.0 4.4 -0.2 2.1 -0.1 0.6 0.6 -1.3 -0.0 1.2
Medication: Blood pressure 0.3 0.6 1.8 1.4 -0.5 -1.2 -0.3 0.2 -0.2 1.0 -0.1
Pain type(s) experienced in last month: Hip pain 2.5 3.1 9.8 -1.2 -0.7 0.4 1.3 -1.8 3.1 -1.0 -2.7
Supplements: Fish oil (including cod liver oil) 0.4 0.5 1.8 0.2 -0.1 -0.7 -0.0 1.4 0.6 1.1 -0.3
High cholesterol (Self-reported) 1.5 2.6 6.8 2.6 -0.7 0.3 -1.9 2.1 -1.2 1.7 0.9
Medication: Bendroflumethiazide 0.5 0.7 2.0 1.0 -0.5 -1.4 -0.5 -0.0 -1.0 0.8 0.7
Medication: Paracetamol 0.7 1.0 2.2 -0.2 1.2 -0.3 0.7 -1.3 1.4 0.2 -1.5
Medication: Lisinopril 0.3 0.4 1.1 0.5 -0.6 -1.0 -0.2 0.1 -1.1 0.6 0.5
Medication: Atorvastatin 1.9 2.4 5.1 1.1 -1.9 -1.2 -0.9 -0.4 2.1 1.5 -2.3
Illnesses of father: High blood pressure 0.9 1.1 3.3 -0.1 1.8 0.1 1.4 -1.7 -0.4 -0.7 0.1
Alcohol drinker status: Never 1.4 1.6 4.6 2.1 0.7 1.0 -0.2 1.8 -0.3 1.9 0.1
Ever smoked 0.2 0.3 0.9 0.4 -0.9 -0.6 -0.2 -0.4 -0.7 -0.1 0.5
Basal metabolic rate 0.4 2.5 6.0 -0.5 1.6 0.8 2.4 -2.2 1.0 -1.8 -1.2
Leg fat percentage (left) 1.1 3.8 14.9 -0.6 1.9 0.3 0.0 -0.1 3.9 -0.1 -3.4
Arm fat-free mass (left) 0.4 1.8 6.0 -0.3 1.7 -0.0 2.4 -1.7 0.5 -1.4 -0.8
Number of operations (self-reported) 1.6 2.3 5.1 1.8 -2.3 1.2 0.1 1.1 1.2 2.1 -1.2
Average weekly beer plus cider intake 0.8 1.2 2.9 1.7 -0.9 0.6 0.0 0.8 1.2 1.2 -1.4
Irritability 0.1 0.1 0.5 0.0 -0.5 0.7 -0.0 -0.3 -0.1 -0.1 0.1
Risk taking 0.9 1.2 3.4 -1.2 0.1 -1.0 1.8 -1.5 0.2 -1.3 -0.2
Ever had prostate specific antigen (PSA) test 1.5 1.7 8.1 -0.6 1.3 -1.1 -2.8 -0.6 -1.0 -0.4 1.0
Fractured/broken bones in last 5 years 1.3 1.7 5.6 0.5 1.1 0.0 2.4 0.2 1.8 0.8 -1.6
Age started oral contraceptive pill 2.2 2.7 10.3 -1.2 0.1 -0.9 -0.2 -0.8 3.2 -0.1 -3.0
Diastolic blood pressure, automated reading 2.1 6.5 14.4 3.2 0.4 -1.6 -1.9 3.8 -2.5 3.2 2.0
Ever depressed for a whole week 1.5 1.8 5.2 0.3 -1.8 1.1 -0.1 0.3 2.3 0.4 -2.2
Unable to work because of sickness or disability 0.5 0.7 2.2 -0.1 0.4 0.1 0.4 -0.9 1.5 -0.1 -1.5
Commuting to job workplace: Cycle 1.7 2.1 6.2 -1.1 -0.3 -0.8 2.5 -0.4 -2.0 -0.7 2.0
Myopia 1.5 2.2 4.8 -1.2 -1.0 -1.2 -2.2 0.5 -1.8 -0.9 2.1
Vascular/heart problems diagnosed by doctor 0.5 1.4 6.0 -1.4 -0.2 2.4 1.3 0.1 0.5 -1.1 0.1
Cholesterol lowering medication 0.8 1.2 2.8 1.5 -0.6 -0.6 -1.4 1.3 0.1 1.7 -0.3
Medication: Omeprazole (e.g. Zanprol) 2.0 2.4 4.7 1.9 -1.0 0.3 0.9 1.1 2.0 2.2 -2.0
Pain experienced in last month 2.2 3.6 8.7 3.0 -0.1 0.6 -2.1 2.7 -1.6 2.2 1.1
Supplements: Calcium 0.1 0.1 0.5 0.2 -0.3 0.3 -0.7 0.0 0.3 0.5 -0.2
Basal cell carcinoma (self-reported) 0.6 0.8 4.0 -0.0 -2.0 -0.7 -1.2 0.1 0.1 0.3 0.1
Heart attack/myocardial infarction (self-reported) 1.2 1.5 3.3 1.5 -0.8 1.2 0.6 0.3 1.7 1.2 -1.8
Deep venous thrombosis (DVT) (self-reported) 1.6 2.0 5.4 1.4 0.4 0.7 0.9 0.5 2.3 1.4 -2.3
Heart disease (siblings) 1.1 1.3 4.5 0.6 -1.7 -0.0 2.1 0.4 1.1 0.5 -1.1
Alcohol drinker status: Previous 1.2 1.4 2.8 0.3 1.7 -1.0 1.2 -0.3 1.6 1.0 -1.5
Pack years of smoking 0.5 0.7 2.0 -0.6 -0.7 -1.4 0.8 -0.8 -0.0 -1.0 0.0
Impedance of whole body 0.8 4.3 9.4 0.8 -0.7 0.9 -2.3 2.6 -3.1 1.3 3.0
Leg fat mass (left) 1.1 4.2 13.8 -0.7 1.9 0.6 1.1 -1.1 3.7 -1.0 -3.5
Arm predicted mass (left) 0.4 1.9 5.8 -0.3 1.8 -0.0 2.4 -1.7 0.5 -1.4 -0.8