TWAS
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Usage
Models
Genes
Traits
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Traits
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Body mass index (BMI)
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chr5:95,168,155-96,832,363
Best TWAS P=1.1e-09 · Best GWAS P=1.12e-10 conditioned to 5.47e-09
95.2M
95.4M
95.6M
95.8M
96M
96.2M
96.4M
96.6M
96.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Liver
CAST
0.32
0.03
enet
23
0.12
4.4e-04
-4.2
-6.1
1.1e-09
-0.11
0.18
0.05
TRUE
1
GTEx
Esophagus Gastroesophageal Junction
ERAP1
0.29
0.18
lasso
8
0.13
2.6e-05
-4.4
-5.1
2.9e-07
-0.04
0.56
0.04
FALSE