[Hub]/) : Traits : Body mass index (BMI) :

chr5:169,590,807-171,533,656

Best TWAS P=6.52e-13 · Best GWAS P=8.46e-14 conditioned to 0.0175

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RANBP17 0.10 0.14 lasso 3 0.13 1.4e-15 -6.1 6.3 2.2e-10 -0.92 0.29 0.71 FALSE
2 GTEx Brain Caudate basal ganglia RANBP17 0.26 0.19 lasso 5 0.14 9.7e-05 -6.2 6.3 3.2e-10 -0.87 0.31 0.56 FALSE
3 GTEx Brain Cerebellar Hemisphere RANBP17 0.20 0.04 lasso 5 0.05 1.6e-02 -6.1 6.5 9.3e-11 -0.89 0.06 0.79 FALSE
4 GTEx Esophagus Muscularis RANBP17 0.12 0.02 lasso 2 0.02 3.5e-02 -6.2 5.9 3.1e-09 -0.89 0.13 0.78 FALSE
5 GTEx Uterus NPM1 0.31 0.17 lasso 9 0.09 7.4e-03 -6.2 6.2 7.1e-10 -0.90 0.12 0.32 FALSE
6 METSIM Adipose RANBP17 0.08 0.06 blup 710 0.06 1.5e-09 -6.2 5.5 4.0e-08 -0.79 0.72 0.28 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma RANBP17 0.02 0.00 blup 135 0.01 3.7e-04 -7.5 7.2 6.5e-13 -0.88 0.02 0.93 TRUE
8 The Cancer Genome Atlas Prostate Adenocarcinoma RANBP17 0.03 0.06 lasso 4 0.05 8.1e-06 -6.2 6.2 5.9e-10 -0.89 0.22 0.78 FALSE