Best TWAS P=2.11e-07 · Best GWAS P=5.36e-07 conditioned to 4.74e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | ZDHHC4 | 0.29 | 0.09 | enet | 19 | 0.13 | 7.5e-08 | 3.8 | -5.1 | 2.8e-07 | -0.27 | 0.44 | 0.30 | FALSE |
2 | GTEx | Breast Mammary Tissue (Female) | PMS2CL | 0.20 | -0.01 | lasso | 4 | -0.01 | 6.7e-01 | 4.6 | -5.2 | 2.1e-07 | -0.09 | 0.02 | 0.14 | TRUE |