TWAS
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Usage
Models
Genes
Traits
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Traits
:
Body mass index (BMI)
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chr7:1,580,921-2,977,732
Best TWAS P=3.32e-08 · Best GWAS P=5.48e-14 conditioned to 0.0543
1.6M
1.8M
2M
2.2M
2.4M
2.6M
2.8M
3M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
MAD1L1
0.09
0.01
blup
206
0.04
0.00011
4.8
-5.5
3.3e-08
0.60
0.09
0.43
TRUE
1
GTEx
Brain Cortex
FTSJ2
0.17
0.01
enet
16
0.06
0.01090
3.7
5.4
5.7e-08
-0.58
0.05
0.60
TRUE