Best TWAS P=2.25e-08 · Best GWAS P=6.91e-09 conditioned to 1.77e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | RMDN1 | 0.18 | 0.08 | lasso | 9 | 0.10 | 1.8e-08 | -5.3 | 5.1 | 3.1e-07 | 0.12 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Stomach | RMDN1 | 0.15 | 0.05 | lasso | 6 | 0.06 | 1.2e-03 | -5.5 | 5.5 | 3.6e-08 | 0.23 | 0.04 | 0.86 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | WWP1 | 0.03 | 0.01 | blup | 63 | 0.02 | 1.8e-03 | -5.0 | -5.2 | 1.8e-07 | -0.14 | 0.02 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | FAM82B | 0.07 | 0.00 | blup | 45 | 0.01 | 1.1e-01 | -5.5 | 5.6 | 2.2e-08 | 0.20 | 0.01 | 0.60 | TRUE |