TWAS
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Traits
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Traits
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Body mass index (BMI)
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chr8:86,841,229-88,211,679
Best TWAS P=2.25e-08 · Best GWAS P=6.91e-09 conditioned to 1.77e-06
86.8M
87M
87.2M
87.4M
87.6M
87.8M
88M
88.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Soft Tissue Sarcoma
FAM82B
0.07
0.00
blup
45
0.01
1.1e-01
-5.5
5.6
2.2e-08
0.20
0.01
0.60
TRUE
2
GTEx
Stomach
RMDN1
0.15
0.05
lasso
6
0.06
1.2e-03
-5.5
5.5
3.6e-08
0.23
0.04
0.86
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
WWP1
0.03
0.01
blup
63
0.02
1.8e-03
-5.0
-5.2
1.8e-07
-0.14
0.02
0.93
FALSE
1
GTEx
Artery Tibial
RMDN1
0.18
0.08
lasso
9
0.10
1.8e-08
-5.3
5.1
3.1e-07
0.12
0.03
0.97
FALSE