Best TWAS P=8.11e-10 · Best GWAS P=1.69e-11 conditioned to 5.86e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | KIAA1429 | 0.10 | 0.10 | lasso | 8 | 0.09 | 1.8e-11 | -5.5 | 5.4 | 6.8e-08 | 0.40 | 0.82 | 0.18 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | KIAA1429 | 0.16 | 0.13 | lasso | 2 | 0.11 | 9.5e-09 | -5.6 | 5.6 | 2.8e-08 | 0.39 | 0.79 | 0.21 | FALSE |
| 3 | GTEx | Testis | KIAA1429 | 0.29 | 0.22 | enet | 21 | 0.22 | 3.3e-10 | -5.6 | 6.1 | 8.1e-10 | 0.43 | 0.46 | 0.54 | TRUE |
| 4 | METSIM | Adipose | KIAA1429 | 0.04 | 0.03 | lasso | 7 | 0.03 | 1.8e-05 | -5.6 | 5.6 | 1.8e-08 | 0.40 | 0.17 | 0.83 | FALSE |
| 5 | METSIM | Adipose | RP11-267M23.4 | 0.04 | 0.04 | lasso | 2 | 0.02 | 1.1e-04 | -5.5 | -5.4 | 6.9e-08 | -0.38 | 0.48 | 0.51 | FALSE |
| 6 | NTR | Blood | RAD54B | 0.03 | 0.02 | lasso | 3 | 0.02 | 3.7e-06 | -5.3 | -5.3 | 9.2e-08 | -0.40 | 0.92 | 0.07 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | KIAA1429 | 0.10 | 0.05 | blup | 57 | 0.08 | 4.1e-08 | -5.6 | 6.0 | 2.4e-09 | 0.62 | 0.26 | 0.74 | FALSE |