TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Body mass index (BMI)
:
←
→
chr9:95,640,381-97,136,378
Best TWAS P=1.34e-13 · Best GWAS P=3.57e-15 conditioned to 0.000433
95.6M
95.8M
96M
96.2M
96.4M
96.6M
96.8M
97M
97.2M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
PHF2
0.07
0.06
lasso
5
0.04
5.5e-04
7.1
7.4
1.3e-13
0.75
0.13
0.81
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
PHF2
0.02
0.01
blup
104
0.01
4.6e-03
7.1
6.6
5.2e-11
0.69
0.11
0.37
FALSE
4
The Cancer Genome Atlas
Lung Adenocarcinoma
PHF2
0.07
0.03
blup
104
0.05
1.9e-06
7.4
6.3
2.8e-10
0.81
0.01
0.99
FALSE
3
The Cancer Genome Atlas
Esophageal Carcinoma
PHF2
0.29
0.14
blup
103
0.16
1.0e-05
7.4
6.3
3.4e-10
0.85
0.00
0.99
FALSE