Best TWAS P=1.34e-13 · Best GWAS P=3.57e-15 conditioned to 0.000433
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PHF2 | 0.07 | 0.06 | lasso | 5 | 0.04 | 5.5e-04 | 7.1 | 7.4 | 1.3e-13 | 0.75 | 0.13 | 0.81 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PHF2 | 0.02 | 0.01 | blup | 104 | 0.01 | 4.6e-03 | 7.1 | 6.6 | 5.2e-11 | 0.69 | 0.11 | 0.37 | FALSE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | PHF2 | 0.29 | 0.14 | blup | 103 | 0.16 | 1.0e-05 | 7.4 | 6.3 | 3.4e-10 | 0.85 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | PHF2 | 0.07 | 0.03 | blup | 104 | 0.05 | 1.9e-06 | 7.4 | 6.3 | 2.8e-10 | 0.81 | 0.01 | 0.99 | FALSE |