[Hub]/) : Traits : Body mass index (BMI) :

chr9:101,974,824-103,803,109

Best TWAS P=2.1e-10 · Best GWAS P=1.85e-10 conditioned to 0.0196

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum STX17 0.14 0.10 lasso 7 0.10 4.6e-06 -4.8 5.1 2.9e-07 0.55 0.94 0.04 FALSE
2 GTEx Artery Aorta INVS 0.15 0.10 enet 19 0.12 4.9e-07 6.3 5.6 2.3e-08 0.72 0.02 0.98 FALSE
3 GTEx Cells Transformed fibroblasts INVS 0.16 0.10 enet 17 0.17 8.0e-13 6.3 5.9 3.9e-09 0.61 0.01 0.99 FALSE
4 GTEx Esophagus Muscularis INVS 0.21 0.16 lasso 5 0.22 8.9e-14 6.3 5.6 1.9e-08 0.73 0.02 0.98 FALSE
5 GTEx Heart Atrial Appendage INVS 0.08 0.03 lasso 3 0.04 4.9e-03 -4.9 5.6 2.0e-08 0.77 0.06 0.88 FALSE
6 GTEx Heart Left Ventricle INVS 0.11 0.05 enet 15 0.04 2.6e-03 2.1 5.4 5.3e-08 0.72 0.04 0.85 FALSE
7 GTEx Muscle Skeletal INVS 0.12 0.03 lasso 10 0.10 1.3e-09 6.3 5.5 4.1e-08 0.73 0.02 0.98 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic TEX10 0.10 0.09 lasso 4 0.10 3.1e-06 4.4 5.7 1.5e-08 0.92 0.03 0.97 FALSE
9 GTEx Skin Sun Exposed Lower leg INVS 0.19 0.06 enet 30 0.11 1.5e-09 6.3 6.0 2.4e-09 0.79 0.01 0.99 FALSE
10 GTEx Skin Sun Exposed Lower leg TEX10 0.27 0.27 lasso 8 0.28 7.0e-23 6.4 6.3 3.5e-10 1.00 0.01 0.99 FALSE
11 GTEx Thyroid INVS 0.22 0.11 enet 18 0.18 5.0e-14 6.3 5.1 2.8e-07 0.65 0.01 0.99 FALSE
12 NTR Blood INVS 0.01 0.01 lasso 4 0.01 3.6e-04 -3.2 5.7 1.4e-08 0.57 0.03 0.91 FALSE
13 YFS Blood INVS 0.15 0.14 lasso 7 0.24 1.4e-77 2.3 5.6 2.3e-08 0.78 0.03 0.97 FALSE
14 The Cancer Genome Atlas Bladder Urothelial Carcinoma INVS 0.27 0.05 lasso 8 0.13 3.4e-11 5.0 5.4 6.3e-08 0.68 0.07 0.93 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma INVS 0.22 0.04 lasso 9 0.07 7.3e-15 6.0 5.3 8.9e-08 0.71 0.04 0.96 FALSE
16 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma INVS 0.10 0.03 blup 107 0.07 4.0e-04 6.0 5.7 1.3e-08 0.89 0.03 0.92 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma INVS 0.08 0.06 blup 106 0.07 7.0e-09 -4.6 5.9 4.8e-09 0.70 0.48 0.52 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma INVS 0.09 0.02 enet 11 0.04 4.0e-05 5.0 5.8 8.4e-09 0.66 0.03 0.71 FALSE
19 The Cancer Genome Atlas Pancreatic Adenocarcinoma INVS 0.16 0.12 enet 8 0.08 2.8e-04 6.0 6.4 2.1e-10 0.77 0.02 0.98 TRUE
20 The Cancer Genome Atlas Prostate Adenocarcinoma INVS 0.09 0.04 enet 14 0.06 1.5e-06 5.0 5.5 3.8e-08 0.75 0.06 0.92 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma INVS 0.21 0.07 enet 13 0.18 4.0e-17 -4.6 5.4 7.0e-08 0.71 0.06 0.94 FALSE