Best TWAS P=1.03e-11 · Best GWAS P=2.14e-15 conditioned to 6.54e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | CKB | 0.28 | 0.26 | lasso | 4 | 0.25 | 6.4e-14 | -5.2 | -5.2 | 1.8e-07 | 0.04 | 0.00 | 1.00 | FALSE |
| 2 | METSIM | Adipose | TRAF3 | 0.04 | 0.02 | enet | 7 | 0.04 | 4.5e-06 | 6.5 | 6.8 | 1.0e-11 | 0.79 | 0.06 | 0.93 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CKB | 0.06 | 0.03 | lasso | 3 | 0.03 | 2.5e-06 | -5.2 | -5.3 | 1.1e-07 | 0.04 | 0.00 | 1.00 | TRUE |