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chr1:242,590,540-244,345,666

Best TWAS P=5.78e-11 · Best GWAS P=1.81e-09 conditioned to 0.12

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells EBV-transformed lymphocytes	SDCCAG8	0.36	0.24	lasso	8	0.34	5.7e-12	4.9	5.5	2.9e-08	-0.29	0.21	0.79	FALSE
2	GTEx	Cells Transformed fibroblasts	SDCCAG8	0.23	0.25	enet	13	0.28	3.5e-21	5.3	5.2	1.7e-07	-0.28	0.16	0.84	FALSE
3	GTEx	Cells Transformed fibroblasts	CEP170	0.21	0.17	enet	15	0.19	5.3e-14	5.3	5.3	1.0e-07	-0.33	0.13	0.87	FALSE
4	GTEx	Cells Transformed fibroblasts	RP11-261C10.5	0.15	0.13	lasso	2	0.14	2.2e-10	5.3	5.3	1.4e-07	-0.29	0.13	0.87	FALSE
5	GTEx	Esophagus Mucosa	CEP170	0.07	0.01	enet	25	0.00	2.5e-01	4.5	5.2	2.2e-07	-0.45	0.09	0.31	FALSE
6	GTEx	Prostate	CEP170	0.28	0.05	lasso	4	0.12	6.9e-04	5.2	5.3	9.3e-08	-0.27	0.10	0.25	FALSE
7	GTEx	Whole Blood	SDCCAG8	0.18	0.15	lasso	7	0.14	6.2e-13	5.0	5.5	4.3e-08	-0.34	0.18	0.82	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SDCCAG8	0.09	0.04	blup	114	0.08	4.6e-07	5.3	6.5	5.8e-11	-0.77	0.12	0.87	TRUE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	SDCCAG8	0.06	0.04	blup	115	0.04	2.0e-08	-5.8	6.0	2.1e-09	-0.84	0.00	1.00	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CEP170	0.03	0.03	enet	4	0.02	7.9e-04	5.3	5.8	7.6e-09	-0.41	0.01	0.98	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SDCCAG8	0.06	0.02	blup	114	0.04	1.9e-05	-4.6	6.2	6.6e-10	-0.80	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	SDCCAG8	0.11	0.04	blup	114	0.06	1.1e-07	-5.6	5.5	3.7e-08	-0.73	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SDCCAG8	0.19	0.18	lasso	5	0.16	1.9e-07	5.0	5.2	2.2e-07	-0.30	0.25	0.71	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	CEP170	0.03	0.01	lasso	4	0.02	4.4e-03	-4.3	5.7	1.5e-08	-0.55	0.02	0.49	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	SDCCAG8	0.10	0.05	lasso	4	0.06	5.8e-07	-4.1	5.7	1.1e-08	-0.71	0.03	0.96	FALSE
16	The Cancer Genome Atlas	Rectum Adenocarcinoma	SDCCAG8	0.30	0.06	blup	113	0.12	8.0e-04	4.8	6.3	3.0e-10	-0.61	0.09	0.33	FALSE