Best TWAS P=1.02e-16 · Best GWAS P=1.28e-25 conditioned to 3.98e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | PPARG | 0.57 | 0.57 | lasso | 5 | 0.54 | 3.6e-16 | -5.6 | -5.7 | 1.6e-08 | -0.11 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Brain Cerebellum | PPARG | 0.64 | 0.57 | lasso | 7 | 0.57 | 4.1e-20 | -5.6 | -6.2 | 6.5e-10 | -0.12 | 1.00 | 0.00 | TRUE |
| 3 | GTEx | Heart Left Ventricle | PPARG | 0.25 | 0.07 | enet | 36 | 0.10 | 5.1e-06 | 10.4 | 8.3 | 1.0e-16 | 0.69 | 0.01 | 0.98 | TRUE |