Best TWAS P=1.74e-08 · Best GWAS P=6.74e-08 conditioned to 0.276
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Stomach | RMDN1 | 0.15 | 0.05 | lasso | 6 | 0.06 | 0.0012 | -5.4 | 5.3 | 9.9e-08 | -0.88 | 0.01 | 0.95 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | WWP1 | 0.03 | 0.01 | blup | 63 | 0.02 | 0.0018 | -4.9 | -5.2 | 2.0e-07 | 0.92 | 0.02 | 0.92 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | WWP1 | 0.05 | 0.01 | enet | 8 | 0.02 | 0.0198 | 4.7 | -5.2 | 2.4e-07 | 0.80 | 0.02 | 0.57 | FALSE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | FAM82B | 0.07 | 0.00 | blup | 45 | 0.01 | 0.1110 | -5.4 | 5.6 | 1.7e-08 | -0.86 | 0.01 | 0.58 | TRUE |