[Hub]/) : Traits : Whole body fat mass :

chr12:109,231,851-111,699,146

Best TWAS P=8.45e-10 · Best GWAS P=2.73e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland PPTC7 0.13 -0.01 lasso 6 0.00 3.4e-01 5.8 5.3 1.4e-07 0.80 0.03 0.35 FALSE
2 GTEx Cells EBV-transformed lymphocytes ARPC3 0.13 0.09 lasso 4 0.04 2.0e-02 5.8 -5.9 4.8e-09 -0.97 0.02 0.88 FALSE
3 GTEx Esophagus Muscularis IFT81 0.26 0.24 lasso 5 0.26 6.7e-16 4.7 5.2 2.4e-07 0.98 0.02 0.98 FALSE
4 GTEx Muscle Skeletal ARPC3 0.14 0.11 enet 23 0.10 2.2e-10 5.7 -5.5 4.6e-08 -0.94 0.02 0.98 FALSE
5 GTEx Muscle Skeletal IFT81 0.08 0.08 lasso 5 0.07 1.7e-07 5.9 6.1 8.4e-10 0.98 0.01 0.99 TRUE
6 GTEx Skin Not Sun Exposed Suprapubic VPS29 0.06 0.01 lasso 3 0.01 6.9e-02 5.8 5.5 3.6e-08 0.90 0.03 0.76 FALSE
7 GTEx Skin Sun Exposed Lower leg ARPC3 0.13 0.15 lasso 3 0.15 1.9e-12 5.7 -5.7 1.3e-08 -0.97 0.03 0.97 FALSE
8 GTEx Spleen VPS29 0.24 0.01 enet 14 0.04 2.9e-02 4.1 5.5 3.0e-08 0.88 0.02 0.73 FALSE
9 GTEx Testis ARPC3 0.16 0.16 lasso 3 0.14 7.5e-07 5.7 -5.7 1.4e-08 -0.97 0.02 0.98 FALSE
10 NTR Blood UBE3B 0.09 0.05 lasso 8 0.08 1.0e-25 4.5 5.7 1.5e-08 0.03 0.01 0.98 TRUE
11 The Cancer Genome Atlas Lung Adenocarcinoma RAD9B 0.04 0.03 lasso 5 0.01 7.0e-03 5.7 5.6 2.7e-08 0.95 0.01 0.99 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma RAD9B 0.10 0.06 enet 5 0.06 1.2e-06 5.7 5.7 1.2e-08 0.97 0.01 0.99 FALSE