[Hub]/) : Traits : Whole body fat mass : ← →

chr12:120,955,578-125,270,773

Best TWAS P=3.15e-22 · Best GWAS P=8.85e-25 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Adipose Visceral Omentum	CCDC92	0.19	0.02	lasso	8	0.09	3.3e-05	6.7	9.7	3.2e-22	-0.12	0.03	0.96	TRUE
18	GTEx	Cells Transformed fibroblasts	BCL7A	0.06	0.01	lasso	4	0.01	3.1e-02	5.0	-8.6	6.1e-18	0.24	0.09	0.05	TRUE
71	The Cancer Genome Atlas	Stomach Adenocarcinoma	MLXIP	0.06	0.02	blup	68	0.04	1.2e-03	7.4	8.6	8.7e-18	-0.23	0.02	0.86	TRUE
24	GTEx	Esophagus Mucosa	HIP1R	0.21	0.05	lasso	5	0.07	1.5e-05	4.4	8.0	1.5e-15	-0.21	0.47	0.26	TRUE
59	The Cancer Genome Atlas	Colon Adenocarcinoma	MLXIP	0.06	0.04	lasso	7	0.02	2.7e-02	7.4	7.4	1.5e-13	-0.17	0.02	0.93	TRUE
4	GTEx	Adipose Subcutaneous	ZCCHC8	0.04	0.00	lasso	7	0.00	1.4e-01	5.9	6.4	2.1e-10	-0.31	0.17	0.10	TRUE
64	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC43	0.03	0.03	enet	8	0.02	1.5e-03	-4.8	-6.3	2.6e-10	0.15	0.10	0.10	TRUE
17	GTEx	Breast Mammary Tissue (Female)	C12orf65	0.06	0.00	enet	13	-0.01	6.5e-01	-4.0	-6.3	3.8e-10	0.27	0.04	0.28	TRUE
2	CommonMind	Brain Pre-frontal Cortex	HIP1R	0.06	0.02	lasso	6	0.04	1.9e-05	-5.8	-5.8	9.2e-09	0.09	0.18	0.02	TRUE
67	The Cancer Genome Atlas	Prostate Adenocarcinoma	GPR81	0.07	0.02	blup	54	0.02	4.4e-03	5.8	5.5	2.8e-08	-0.13	0.04	0.20	TRUE
9	GTEx	Artery Aorta	P2RX4	0.20	0.03	enet	28	0.05	1.6e-03	-2.9	-5.3	8.7e-08	0.02	0.15	0.50	TRUE
37	GTEx	Skin Not Sun Exposed Suprapubic	WDR66	0.23	0.03	lasso	3	0.06	2.5e-04	-5.2	5.3	1.1e-07	-0.07	0.46	0.02	TRUE
10	GTEx	Artery Coronary	WDR66	0.25	0.14	lasso	5	0.17	2.1e-06	-4.3	-5.3	1.3e-07	0.00	0.53	0.02	TRUE
53	YFS	Blood	MORN3	0.12	0.13	lasso	7	0.15	4.9e-48	5.6	5.1	3.1e-07	-0.09	1.00	0.00	TRUE
8	GTEx	Adipose Visceral Omentum	RP11-380L11.3	0.15	0.03	lasso	5	0.01	1.4e-01	6.7	9.5	1.9e-21	-0.08	0.02	0.86	FALSE
6	GTEx	Adipose Subcutaneous	RP11-380L11.3	0.09	0.03	lasso	3	0.03	1.4e-03	6.6	8.8	8.5e-19	-0.07	0.05	0.94	FALSE
5	GTEx	Adipose Subcutaneous	CCDC92	0.23	0.04	enet	27	0.16	6.9e-13	-5.9	8.7	3.0e-18	-0.09	0.03	0.97	FALSE
48	METSIM	Adipose	CCDC92	0.10	0.01	bslmm	435	0.06	5.5e-10	-3.6	8.3	1.1e-16	-0.08	0.02	0.98	FALSE
44	GTEx	Thyroid	CCDC92	0.06	0.03	lasso	3	0.02	1.1e-02	6.7	8.2	2.8e-16	-0.08	0.06	0.89	FALSE
47	METSIM	Adipose	ABCB9	0.04	0.03	enet	19	0.03	7.7e-05	-5.8	-7.9	2.1e-15	0.38	0.08	0.65	FALSE
33	GTEx	Nerve Tibial	CCDC92	0.16	0.01	enet	6	0.04	6.7e-04	5.7	7.6	2.3e-14	-0.10	0.10	0.52	FALSE
27	GTEx	Heart Atrial Appendage	RP11-380L11.4	0.18	0.11	lasso	7	0.12	6.5e-06	6.7	7.5	4.8e-14	-0.07	0.05	0.94	FALSE
29	GTEx	Lung	CCDC92	0.14	0.00	enet	10	0.01	1.1e-01	7.2	7.4	1.2e-13	-0.08	0.01	0.95	FALSE
28	GTEx	Heart Left Ventricle	CCDC92	0.26	0.19	lasso	4	0.21	1.9e-11	5.8	7.4	1.8e-13	-0.06	0.15	0.85	FALSE
52	METSIM	Adipose	RP11-214K3.24	0.05	0.03	bslmm	444	0.02	2.7e-04	5.8	7.3	2.4e-13	-0.07	0.08	0.88	FALSE
20	GTEx	Colon Transverse	MLXIP	0.20	0.18	enet	23	0.14	5.8e-07	7.5	7.3	2.7e-13	-0.17	1.00	0.00	FALSE
34	GTEx	Nerve Tibial	KNTC1	0.12	0.05	lasso	5	0.05	1.9e-04	-6.6	-7.3	3.1e-13	0.31	0.53	0.03	FALSE
74	The Cancer Genome Atlas	Thyroid Carcinoma	VPS33A	0.06	0.00	enet	8	0.03	9.6e-04	5.8	-7.2	4.6e-13	0.20	0.06	0.93	FALSE
70	The Cancer Genome Atlas	Rectum Adenocarcinoma	MLXIP	0.18	0.14	lasso	4	0.13	5.1e-04	6.7	7.2	8.3e-13	-0.16	0.02	0.90	FALSE
31	GTEx	Muscle Skeletal	RSRC2	0.06	0.03	enet	7	0.04	9.6e-05	-3.6	-7.1	1.0e-12	0.43	0.25	0.48	FALSE
21	GTEx	Colon Transverse	SNRNP35	0.18	0.02	lasso	8	0.04	6.5e-03	-4.1	7.1	1.1e-12	-0.16	0.06	0.30	FALSE
56	The Cancer Genome Atlas	Breast Invasive Carcinoma	DNAH10	0.11	0.03	blup	99	0.05	8.2e-11	5.5	7.1	1.7e-12	-0.05	0.03	0.97	FALSE
19	GTEx	Colon Sigmoid	RP11-380L11.4	0.21	0.12	lasso	3	0.08	1.1e-03	6.6	6.8	9.4e-12	-0.06	0.06	0.84	FALSE
75	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF664	0.06	0.05	enet	9	0.05	2.8e-05	6.6	-6.8	1.4e-11	0.08	0.05	0.95	FALSE
22	GTEx	Esophagus Mucosa	KDM2B	0.11	0.04	enet	22	0.10	4.1e-07	2.5	6.7	2.0e-11	-0.10	0.92	0.01	FALSE
25	GTEx	Esophagus Muscularis	RP11-380L11.4	0.27	0.29	lasso	8	0.27	1.0e-16	6.7	6.6	3.2e-11	-0.05	0.06	0.94	FALSE
30	GTEx	Lung	RP11-380L11.4	0.07	0.07	lasso	3	0.07	8.2e-06	6.8	6.6	3.3e-11	-0.06	0.06	0.94	FALSE
62	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DNAH10	0.07	0.03	lasso	3	0.05	7.4e-06	6.7	6.6	3.4e-11	-0.06	0.03	0.97	FALSE
13	GTEx	Brain Putamen basal ganglia	WDR66	0.25	0.01	enet	16	-0.01	5.6e-01	7.1	-6.5	5.8e-11	0.15	0.06	0.23	FALSE
11	GTEx	Artery Tibial	RP11-380L11.4	0.14	0.12	lasso	4	0.12	2.2e-09	6.6	6.5	8.3e-11	-0.04	0.07	0.93	FALSE
45	GTEx	Thyroid	ZNF664	0.13	0.06	lasso	11	0.08	6.7e-07	5.6	-6.5	8.3e-11	0.04	0.09	0.91	FALSE
26	GTEx	Heart Atrial Appendage	CCDC92	0.12	0.11	enet	9	0.11	1.1e-05	5.0	6.4	1.4e-10	-0.05	0.12	0.83	FALSE
14	GTEx	Breast Mammary Tissue (Male)	CCDC92	0.06	-0.01	lasso	3	0.00	4.3e-01	5.7	6.4	1.8e-10	-0.07	0.04	0.11	FALSE
68	The Cancer Genome Atlas	Prostate Adenocarcinoma	LRRC43	0.04	0.00	blup	58	0.01	6.9e-02	7.1	-6.3	2.6e-10	0.12	0.02	0.24	FALSE
57	The Cancer Genome Atlas	Breast Invasive Carcinoma	VPS33A	0.01	0.02	lasso	2	0.02	2.7e-04	6.2	-6.3	2.7e-10	0.14	0.28	0.36	FALSE
51	METSIM	Adipose	MORN3	0.06	0.02	lasso	10	0.04	8.7e-07	5.6	6.3	3.0e-10	-0.05	0.95	0.00	FALSE
69	The Cancer Genome Atlas	Prostate Adenocarcinoma	VPS33A	0.04	0.05	lasso	1	0.04	3.0e-05	6.2	-6.2	4.2e-10	0.13	0.67	0.32	FALSE
61	The Cancer Genome Atlas	Glioblastoma Multiforme	CCDC92	0.07	0.02	blup	52	0.04	1.8e-02	5.6	6.2	5.6e-10	-0.05	0.04	0.57	FALSE
72	The Cancer Genome Atlas	Thyroid Carcinoma	DNAH10	0.04	0.03	lasso	5	0.02	4.6e-03	5.7	6.2	6.6e-10	-0.05	0.02	0.81	FALSE
54	YFS	Blood	PSMD9	0.04	0.03	bslmm	324	0.05	8.2e-15	-6.0	6.2	7.8e-10	-0.08	1.00	0.00	FALSE
43	GTEx	Testis	ABCB9	0.14	0.05	lasso	3	0.06	8.0e-04	7.1	-6.1	8.1e-10	0.22	0.25	0.05	FALSE
36	GTEx	Prostate	CCDC92	0.31	0.10	enet	42	0.11	9.0e-04	5.6	6.1	1.3e-09	-0.08	0.08	0.64	FALSE
23	GTEx	Esophagus Mucosa	CCDC92	0.11	0.02	lasso	4	0.02	1.9e-02	5.8	6.0	1.6e-09	-0.05	0.16	0.65	FALSE
55	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LRRC43	0.06	0.03	enet	6	0.03	8.7e-04	-4.9	-6.0	2.0e-09	0.10	0.12	0.24	FALSE
12	GTEx	Brain Cerebellar Hemisphere	WDR66	0.28	0.05	lasso	8	0.04	3.6e-02	-4.3	-5.9	3.0e-09	0.10	0.08	0.19	FALSE
73	The Cancer Genome Atlas	Thyroid Carcinoma	PSMD9	0.09	0.10	lasso	4	0.10	7.4e-10	-5.9	5.9	3.5e-09	-0.02	0.01	0.99	FALSE
65	The Cancer Genome Atlas	Brain Lower Grade Glioma	VPS33A	0.03	0.05	lasso	1	0.05	4.4e-06	5.8	-5.8	5.6e-09	0.13	0.83	0.13	FALSE
16	GTEx	Breast Mammary Tissue (Female)	CCDC92	0.05	-0.01	enet	2	-0.01	6.2e-01	5.6	5.7	1.6e-08	-0.04	0.04	0.20	FALSE
42	GTEx	Stomach	RP11-347I19.8	0.22	0.09	lasso	7	0.11	4.2e-06	3.9	-5.6	1.9e-08	-0.02	0.95	0.02	FALSE
50	METSIM	Adipose	DNAH10	0.03	0.00	bslmm	475	0.01	3.2e-03	7.0	5.6	1.9e-08	-0.01	0.03	0.83	FALSE
35	GTEx	Pancreas	RP11-347I19.8	0.12	0.00	enet	13	0.00	2.9e-01	3.9	-5.6	2.2e-08	0.00	0.10	0.05	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CCDC62	0.12	0.06	enet	21	0.06	3.3e-08	4.6	-5.6	2.7e-08	0.13	0.99	0.00	FALSE
66	The Cancer Genome Atlas	Lung Adenocarcinoma	LOC338799	0.04	0.02	blup	29	0.04	3.5e-05	3.9	-5.5	2.8e-08	-0.03	0.12	0.57	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TMEM120B	0.11	0.04	lasso	3	0.08	1.9e-09	4.5	5.5	3.3e-08	-0.03	1.00	0.00	FALSE
40	GTEx	Skin Sun Exposed Lower leg	RP11-380L11.4	0.04	0.02	enet	15	0.02	1.9e-02	6.8	5.4	6.1e-08	-0.04	0.05	0.88	FALSE
58	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC338799	0.06	0.03	blup	31	0.05	5.2e-04	4.5	-5.4	7.6e-08	-0.02	0.03	0.45	FALSE
41	GTEx	Stomach	AC084018.1	0.13	0.13	enet	23	0.13	8.7e-07	3.9	-5.3	9.4e-08	-0.01	0.79	0.02	FALSE
60	The Cancer Genome Atlas	Esophageal Carcinoma	LOC338799	0.10	0.02	blup	30	0.06	6.9e-03	5.2	-5.3	1.2e-07	-0.01	0.00	0.74	FALSE
46	GTEx	Whole Blood	DDX55	0.13	0.04	enet	13	0.06	3.3e-06	-3.0	5.2	2.1e-07	-0.17	0.34	0.02	FALSE
49	METSIM	Adipose	CLIP1	0.03	0.01	bslmm	372	0.01	3.3e-03	-5.4	5.2	2.3e-07	-0.31	0.60	0.04	FALSE
63	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC338799	0.06	0.09	lasso	6	0.10	2.1e-11	3.9	-5.2	2.3e-07	-0.03	0.22	0.74	FALSE
32	GTEx	Muscle Skeletal	RP11-347I19.8	0.08	0.06	lasso	4	0.06	2.4e-06	3.4	-5.2	2.5e-07	0.03	0.96	0.01	FALSE
38	GTEx	Skin Not Sun Exposed Suprapubic	KNTC1	0.11	0.04	lasso	4	0.03	7.1e-03	5.6	-5.2	2.6e-07	0.14	0.22	0.04	FALSE
39	GTEx	Skin Sun Exposed Lower leg	WDR66	0.19	0.10	lasso	5	0.08	5.5e-07	3.2	5.1	3.0e-07	-0.11	0.99	0.00	FALSE
15	GTEx	Breast Mammary Tissue (Female)	KDM2B	0.13	0.00	lasso	3	0.01	1.2e-01	-3.7	5.1	3.1e-07	-0.12	0.04	0.19	FALSE