[Hub]/) : Traits : Whole body fat mass : ← →

chr1:76,862,305-79,300,939

Best TWAS P=2.14e-10 · Best GWAS P=3.67e-24 conditioned to 3.63e-16

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Coronary PIGK 0.22 0.00 lasso 8 -0.01 9.0e-01 5.1 -5.5 4.0e-08 -0.10 0.08 0.06 TRUE
2 GTEx Lung GIPC2 0.15 0.09 enet 17 0.12 2.5e-09 -4.1 5.1 2.7e-07 0.19 1.00 0.00 FALSE
3 GTEx Nerve Tibial DNAJB4 0.08 0.07 lasso 3 0.07 1.3e-05 -5.0 -5.2 1.8e-07 -0.14 0.82 0.01 FALSE
4 GTEx Spleen GIPC2 0.43 0.07 enet 19 0.22 2.9e-06 -5.6 5.9 3.1e-09 0.22 0.83 0.02 FALSE
5 METSIM Adipose DNAJB4 0.04 0.04 lasso 4 0.03 2.1e-05 -5.0 -5.5 4.4e-08 -0.26 0.70 0.01 FALSE
6 ROSMAP Brain Pre-frontal Cortex DNAJB4 0.08 0.09 lasso 2 0.09 1.3e-11 -5.3 -5.4 8.2e-08 -0.18 1.00 0.00 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma GIPC2 0.04 0.01 blup 65 0.00 2.5e-01 -4.9 6.4 2.1e-10 0.28 0.07 0.06 TRUE
8 The Cancer Genome Atlas Brain Lower Grade Glioma GIPC2 0.02 0.02 lasso 3 0.02 1.0e-03 -5.5 5.5 3.0e-08 0.22 0.37 0.02 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma DNAJB4 0.04 0.04 lasso 2 0.04 1.2e-05 5.8 -5.9 4.4e-09 -0.45 0.00 1.00 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma GIPC2 0.07 0.05 blup 64 0.06 1.5e-06 -4.3 5.2 2.2e-07 0.28 0.67 0.02 FALSE