TWAS
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Traits
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Traits
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Whole body fat mass
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chr14:72,695,406-74,192,791
Best TWAS P=1.11e-08 · Best GWAS P=3.16e-06 conditioned to 1.03e-05
72.8M
73M
73.2M
73.4M
73.6M
73.8M
74M
74.2M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Gastroesophageal Junction
DCAF4
0.18
0.01
enet
10
0.06
3.0e-03
4.0
5.7
1.1e-08
-0.04
0.02
0.17
TRUE
3
GTEx
Esophagus Mucosa
ZFYVE1
0.10
0.00
lasso
7
0.00
2.0e-01
4.0
5.3
9.6e-08
-0.12
0.03
0.34
FALSE
1
GTEx
Adipose Visceral Omentum
DCAF4
0.23
0.07
enet
30
0.13
4.3e-07
3.8
5.1
2.6e-07
-0.11
0.05
0.62
FALSE