TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
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→
chr14:93,011,368-94,495,324
Best TWAS P=9.04e-11 · Best GWAS P=3.69e-15 conditioned to 0.000444
93M
93.2M
93.4M
93.6M
93.8M
94M
94.2M
94.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
BTBD7
0.16
0.01
lasso
8
0.04
3.6e-04
-6.5
6.5
9.0e-11
-0.58
0.10
0.88
TRUE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
C14orf142
0.11
0.04
enet
7
0.05
7.2e-07
4.0
-6.0
2.1e-09
0.22
0.51
0.08
TRUE
4
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
BTBD7
0.02
0.01
blup
72
0.02
6.8e-03
-6.5
6.3
3.7e-10
-0.80
0.01
0.89
FALSE
5
The Cancer Genome Atlas
Testicular Germ Cell Tumors
BTBD7
0.11
0.03
blup
72
0.02
8.0e-02
-6.5
6.1
9.0e-10
-0.56
0.02
0.77
FALSE
2
GTEx
Testis
BTBD7
0.19
0.00
enet
45
0.01
9.5e-02
-4.5
5.9
4.8e-09
-0.56
0.04
0.88
FALSE