TWAS
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Usage
Models
Genes
Traits
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Traits
:
Whole body fat mass
:
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chr14:101,720,669-104,074,810
Best TWAS P=8.48e-11 · Best GWAS P=8.97e-15 conditioned to 4.28e-06
102M
102.5M
103M
103.5M
104M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
METSIM
Adipose
TRAF3
0.04
0.02
enet
7
0.04
4.5e-06
6.0
6.5
8.5e-11
0.79
0.04
0.95
TRUE
1
GTEx
Esophagus Mucosa
RP11-1017G21.6
0.14
0.04
lasso
3
0.02
8.6e-03
-4.3
-5.4
7.3e-08
0.03
0.03
0.76
TRUE