[Hub]/) : Traits : Whole body fat mass : ← →

chr2:171,867,383-173,555,880

Best TWAS P=8.23e-09 · Best GWAS P=6.44e-09 conditioned to 0.0532

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	ROSMAP	Brain Pre-frontal Cortex	AC068039.4	0.43	0.64	enet	35	0.65	1.6e-110	-5.5	-5.8	8.2e-09	0.81	0.04	0.96	TRUE
3	GTEx	Muscle Skeletal	DYNC1I2	0.11	0.12	lasso	2	0.12	6.5e-12	-5.6	5.7	1.3e-08	-0.84	0.04	0.96	FALSE
11	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MAP1D	0.03	0.03	lasso	2	0.02	1.5e-03	-5.7	5.6	2.1e-08	-0.68	0.00	0.98	FALSE
5	GTEx	Testis	DYNC1I2	0.13	0.02	lasso	4	0.01	1.1e-01	-5.6	5.5	2.8e-08	-0.81	0.04	0.78	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	DYNC1I2	0.02	0.00	blup	45	0.00	3.6e-02	-5.5	5.5	3.3e-08	-0.58	0.01	0.63	FALSE
2	GTEx	Cells Transformed fibroblasts	DYNC1I2	0.12	0.14	lasso	3	0.14	1.4e-10	-5.5	5.5	3.4e-08	-0.81	0.04	0.96	FALSE
8	YFS	Blood	SLC25A12	0.09	0.15	lasso	7	0.15	1.3e-45	-5.5	-5.5	3.4e-08	0.82	0.04	0.96	FALSE
4	GTEx	Skin Sun Exposed Lower leg	DYNC1I2	0.11	0.16	lasso	1	0.15	8.9e-13	-5.5	5.5	3.9e-08	-0.80	0.04	0.96	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DYNC1I2	0.05	0.06	lasso	4	0.05	6.3e-06	-5.6	5.3	1.3e-07	-0.80	0.02	0.98	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	SLC25A12	0.13	0.08	lasso	6	0.11	1.8e-13	-5.5	-5.2	1.7e-07	0.86	0.03	0.97	FALSE
1	GTEx	Brain Cerebellar Hemisphere	DYNC1I2	0.32	0.24	lasso	7	0.26	2.0e-07	-4.6	5.2	2.0e-07	-0.79	0.05	0.94	FALSE