[Hub]/) : Traits : Whole body fat mass : ← →

chr2:171,867,383-173,555,880

Best TWAS P=8.23e-09 · Best GWAS P=6.44e-09 conditioned to 0.0532

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere DYNC1I2 0.32 0.24 lasso 7 0.26 2.0e-07 -4.6 5.2 2.0e-07 -0.79 0.05 0.94 FALSE
2 GTEx Cells Transformed fibroblasts DYNC1I2 0.12 0.14 lasso 3 0.14 1.4e-10 -5.5 5.5 3.4e-08 -0.81 0.04 0.96 FALSE
3 GTEx Muscle Skeletal DYNC1I2 0.11 0.12 lasso 2 0.12 6.5e-12 -5.6 5.7 1.3e-08 -0.84 0.04 0.96 FALSE
4 GTEx Skin Sun Exposed Lower leg DYNC1I2 0.11 0.16 lasso 1 0.15 8.9e-13 -5.5 5.5 3.9e-08 -0.80 0.04 0.96 FALSE
5 GTEx Testis DYNC1I2 0.13 0.02 lasso 4 0.01 1.1e-01 -5.6 5.5 2.8e-08 -0.81 0.04 0.78 FALSE
6 ROSMAP Brain Pre-frontal Cortex SLC25A12 0.13 0.08 lasso 6 0.11 1.8e-13 -5.5 -5.2 1.7e-07 0.86 0.03 0.97 FALSE
7 ROSMAP Brain Pre-frontal Cortex AC068039.4 0.43 0.64 enet 35 0.65 1.6e-110 -5.5 -5.8 8.2e-09 0.81 0.04 0.96 TRUE
8 YFS Blood SLC25A12 0.09 0.15 lasso 7 0.15 1.3e-45 -5.5 -5.5 3.4e-08 0.82 0.04 0.96 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma DYNC1I2 0.02 0.00 blup 45 0.00 3.6e-02 -5.5 5.5 3.3e-08 -0.58 0.01 0.63 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DYNC1I2 0.05 0.06 lasso 4 0.05 6.3e-06 -5.6 5.3 1.3e-07 -0.80 0.02 0.98 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MAP1D 0.03 0.03 lasso 2 0.02 1.5e-03 -5.7 5.6 2.1e-08 -0.68 0.00 0.98 FALSE