TWAS
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Models
Genes
Traits
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Traits
:
Whole body fat mass
:
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chr3:40,537,829-41,986,787
Best TWAS P=4.57e-09 · Best GWAS P=3.1e-09 conditioned to 0.126
40.6M
40.8M
41M
41.2M
41.4M
41.6M
41.8M
42M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
NTR
Blood
CTNNB1
0.04
0.04
lasso
6
0.04
4.6e-13
5.6
-5.9
4.6e-09
-0.89
0.02
0.98
TRUE
2
GTEx
Nerve Tibial
CTNNB1
0.05
0.00
enet
4
0.00
2.0e-01
5.6
5.7
9.3e-09
0.69
0.04
0.76
FALSE
1
GTEx
Artery Coronary
CTNNB1
0.30
0.00
lasso
4
0.01
1.0e-01
5.8
-5.3
9.2e-08
-0.93
0.03
0.50
FALSE