TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
←
→
chr3:84,767,271-86,367,480
Best TWAS P=8.68e-12 · Best GWAS P=5.97e-16 conditioned to 2.3e-06
84.8M
85M
85.2M
85.4M
85.6M
85.8M
86M
86.2M
86.4M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Brain Lower Grade Glioma
CADM2
0.06
0.00
blup
339
0.00
2.7e-01
-5
-6.8
8.7e-12
0.67
0.04
0.43
TRUE
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
CADM2
0.05
0.03
lasso
3
0.04
5.0e-05
5
5.7
1.0e-08
-0.31
0.92
0.02
FALSE
2
The Cancer Genome Atlas
Lung Adenocarcinoma
CADM2
0.08
0.04
lasso
4
0.05
2.1e-06
5
5.7
1.5e-08
-0.36
0.98
0.00
FALSE