[Hub]/) : Traits : Whole body fat mass :

chr3:87,495,550-88,911,119

Best TWAS P=1.36e-09 · Best GWAS P=1.44e-09 conditioned to 0.00737

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C3orf38 0.08 0.00 enet 14 0.04 2.3e-05 -5.8 -5.8 6.3e-09 0.56 0.05 0.91 FALSE
2 GTEx Artery Aorta C3orf38 0.06 0.06 lasso 7 0.05 6.0e-04 -5.8 5.8 5.9e-09 -0.67 0.05 0.92 FALSE
3 GTEx Cells Transformed fibroblasts ZNF654 0.08 0.09 enet 6 0.10 3.1e-08 -5.8 -5.9 3.5e-09 0.57 0.04 0.96 FALSE
4 GTEx Esophagus Mucosa C3orf38 0.11 0.06 lasso 7 0.07 1.5e-05 -5.7 6.1 1.4e-09 -0.67 0.05 0.94 TRUE
5 GTEx Nerve Tibial C3orf38 0.09 0.05 lasso 4 0.04 6.3e-04 -5.8 5.8 5.9e-09 -0.68 0.05 0.93 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic ZNF654 0.09 0.01 lasso 7 0.06 2.7e-04 -5.8 -5.4 5.4e-08 0.64 0.04 0.67 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic C3orf38 0.09 0.07 lasso 6 0.04 2.8e-03 -5.7 5.8 8.8e-09 -0.68 0.05 0.88 FALSE
8 GTEx Testis C3orf38 0.11 0.01 enet 12 0.00 1.9e-01 -5.4 5.5 4.2e-08 -0.72 0.09 0.43 FALSE
9 GTEx Thyroid C3orf38 0.12 0.08 lasso 18 0.07 1.0e-05 -5.7 5.7 9.7e-09 -0.68 0.06 0.94 FALSE
10 GTEx Uterus ZNF654 0.29 -0.01 lasso 4 0.01 1.7e-01 -5.8 -5.4 7.7e-08 0.66 0.04 0.61 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma C3orf38 0.01 0.01 lasso 3 0.01 1.2e-03 -5.7 5.6 1.8e-08 -0.65 0.02 0.67 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C3orf38 0.02 0.01 blup 24 0.02 2.0e-03 -5.7 5.6 2.2e-08 -0.65 0.02 0.75 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf38 0.02 0.03 lasso 1 0.03 1.9e-04 -5.8 5.8 5.9e-09 -0.69 0.02 0.79 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma C3orf38 0.03 0.05 lasso 1 0.05 8.1e-06 -5.8 5.8 5.9e-09 -0.69 0.02 0.97 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma ZNF654 0.03 0.04 lasso 3 0.03 4.6e-04 -5.8 -5.8 5.1e-09 0.69 0.02 0.94 FALSE