[Hub]/) : Traits : Whole body fat mass : ← →

chr3:182,655,858-184,256,798

Best TWAS P=6.95e-10 · Best GWAS P=7.79e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Adipose Subcutaneous	KLHL24	0.15	0.10	lasso	6	0.10	1.4e-08	-5.7	6.2	6.9e-10	-0.99	0.02	0.98	TRUE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	ECE2	0.04	0.02	blup	61	0.03	3.5e-04	4.5	5.3	8.9e-08	-0.16	0.02	0.93	TRUE
6	GTEx	Brain Cortex	KLHL24	0.21	0.15	lasso	3	0.07	6.1e-03	-5.7	6.1	1.0e-09	-0.98	0.03	0.93	FALSE
9	GTEx	Breast Mammary Tissue	KLHL24	0.25	0.13	lasso	5	0.11	3.4e-06	-5.8	5.9	4.1e-09	-0.98	0.02	0.98	FALSE
5	GTEx	Brain Cerebellum	KLHL24	0.52	0.14	enet	26	0.16	1.9e-05	-5.8	5.8	6.4e-09	-0.89	0.02	0.97	FALSE
10	GTEx	Esophagus Muscularis	KLHL24	0.10	0.12	lasso	1	0.09	4.4e-06	-5.8	5.8	7.8e-09	-1.00	0.02	0.98	FALSE
3	GTEx	Brain Caudate basal ganglia	KLHL24	0.22	0.21	lasso	3	0.19	3.5e-06	-5.8	5.8	7.9e-09	-1.00	0.02	0.96	FALSE
13	GTEx	Testis	KLHL24	0.17	0.10	lasso	4	0.10	4.0e-05	-5.8	5.8	8.0e-09	-1.00	0.02	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	KLHL24	0.42	0.60	bslmm	493	0.66	4.5e-107	-5.7	-5.7	9.2e-09	0.93	0.02	0.98	FALSE
11	GTEx	Nerve Tibial	KLHL24	0.08	0.06	lasso	3	0.05	1.5e-04	-5.7	5.7	1.1e-08	-0.98	0.02	0.96	FALSE
12	GTEx	Skin Sun Exposed Lower leg	KLHL24	0.09	0.06	lasso	10	0.05	9.5e-05	-5.7	5.7	1.4e-08	-0.99	0.02	0.97	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	KLHL24	0.05	0.05	blup	53	0.05	1.1e-06	-5.7	5.6	1.9e-08	-0.94	0.02	0.98	FALSE
14	METSIM	Adipose	MAP6D1	0.06	0.05	bslmm	473	0.06	2.3e-09	5.4	5.4	6.1e-08	-0.17	0.45	0.55	FALSE
17	The Cancer Genome Atlas	Testicular Germ Cell Tumors	KLHL24	0.16	0.16	blup	53	0.21	4.3e-08	-5.7	5.4	6.9e-08	-0.95	0.02	0.98	FALSE
7	GTEx	Brain Frontal Cortex BA9	KLHL24	0.36	0.23	lasso	6	0.15	9.3e-05	-5.7	5.4	7.1e-08	-0.94	0.02	0.96	FALSE
4	GTEx	Brain Cerebellar Hemisphere	KLHL24	0.31	0.10	enet	22	0.09	3.4e-03	-5.8	5.3	1.2e-07	-0.77	0.02	0.92	FALSE
8	GTEx	Brain Hypothalamus	KLHL24	0.22	0.24	lasso	2	0.19	3.3e-05	-5.1	5.1	3.1e-07	-0.70	0.05	0.68	FALSE