TWAS hub - MAP6D1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Coronary	0.1890	0.0890	7.7e-03	-0.007	NA	-0.006	NA	-0.009	6.2e-01	NA	6.0e-01	NA	9.8e-01
2	GTEx	Artery Tibial	0.1276	0.0425	1.0e-05	0.065	NA	0.068	NA	0.059	7.9e-06	NA	5.1e-06	NA	2.1e-05
3	GTEx	Brain Caudate basal ganglia	0.1450	0.0690	9.0e-03	0.060	NA	0.005	NA	0.018	8.5e-03	NA	2.2e-01	NA	9.9e-02
4	GTEx	Brain Cerebellar Hemisphere	0.1960	0.0730	1.5e-03	0.032	NA	0.042	NA	0.064	5.3e-02	NA	3.1e-02	NA	1.0e-02
5	GTEx	Brain Cerebellum	0.3840	0.0880	5.9e-08	0.268	NA	0.336	NA	0.315	1.5e-08	NA	1.1e-10	NA	5.0e-10
6	GTEx	Brain Nucleus accumbens basal ganglia	0.1950	0.0930	5.6e-03	-0.002	NA	0.002	NA	0.001	3.7e-01	NA	2.8e-01	NA	2.9e-01
7	GTEx	Cells Transformed fibroblasts	0.0890	0.0330	4.3e-04	0.025	NA	0.027	NA	0.031	5.1e-03	NA	3.8e-03	NA	2.0e-03
8	GTEx	Esophagus Mucosa	0.0820	0.0280	1.1e-04	0.075	NA	0.057	NA	0.066	1.0e-05	NA	1.0e-04	NA	3.4e-05
9	GTEx	Skin Not Sun Exposed Suprapubic	0.1610	0.0500	1.5e-05	0.077	NA	0.056	NA	0.028	5.3e-05	NA	4.8e-04	NA	1.1e-02
10	GTEx	Skin Sun Exposed Lower leg	0.0650	0.0300	3.1e-03	0.022	NA	0.016	NA	0.027	5.7e-03	NA	1.5e-02	NA	2.7e-03
11	METSIM	Adipose	0.0642	0.0200	1.9e-07	0.052	0.060	0.050	0.060	0.056	2.8e-08	2.7e-09	5.6e-08	2.3e-09	7.2e-09
12	YFS	Blood	0.2462	0.0298	0.0e+00	0.233	0.301	0.318	0.311	0.317	4.6e-75	1.5e-100	5.3e-107	2.7e-104	9.4e-107
13	TCGA	Cervical Squamous Cell Carcinoma	0.0690	0.0380	2.4e-04	0.059	0.056	0.049	NA	0.054	7.5e-04	9.4e-04	1.9e-03	NA	1.2e-03
14	TCGA	Glioblastoma Multiforme	0.1980	0.1020	1.4e-03	0.053	-0.003	0.053	NA	-0.009	1.0e-02	4.1e-01	1.0e-02	NA	8.2e-01
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.0404	0.0213	3.2e-05	0.014	0.038	0.026	NA	0.025	8.5e-03	4.0e-05	6.2e-04	NA	6.9e-04
16	TCGA	Brain Lower Grade Glioma	0.0315	0.0179	3.1e-05	0.042	0.047	0.051	NA	0.050	1.3e-05	4.8e-06	1.8e-06	NA	2.2e-06
17	TCGA	Thyroid Carcinoma	0.1430	0.0690	6.3e-07	0.032	0.059	0.070	NA	0.064	4.0e-04	1.9e-06	2.6e-07	NA	7.6e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Ever smoked	7.6	13.4	22.5	-4.0	-3.4	-4.6	-3.3	-1.8	3.5	4.2	3.9	3.6	-3.9	-3.0	4.4	2.8	4.4	4.7	3.6
Smoking status: Previous	6.5	9.8	19.5	-3.1	-3.5	-4.4	-3.2	-3.5	2.9	3.2	3.2	2.4	-2.8	-1.1	3.7	1.0	4.4	3.4	3.5
Blood Platelet Count	6.3	72.9	176.9	-11.4	-4.5	-9.3	-7.3	-1.9	6.5	9.8	8.4	8.1	-13.3	-6.6	10.0	5.7	9.8	11.2	9.8
Past tobacco smoking	6.3	11.6	20.6	3.5	3.7	4.5	3.2	3.0	-2.9	-3.7	-3.8	-3.1	3.4	1.9	-4.2	-1.9	-4.5	-4.2	-3.4
Chest pain or discomfort	5.9	8.6	14.4	3.5	2.3	2.3	3.0	1.1	-2.3	-3.6	-3.0	-3.5	3.5	3.0	-3.3	-3.1	-2.7	-3.8	-3.0
Supplements: Calcium	5.8	6.3	10.1	-3.1	-2.2	-2.8	-2.5	-1.3	2.3	2.8	2.4	3.2	-2.9	-1.9	3.0	1.6	3.1	2.9	2.7
Illnesses of father: High blood pressure	5.6	6.9	10.4	3.0	2.9	2.3	2.8	0.9	-3.2	-3.2	-3.2	-2.6	2.0	2.7	-3.0	-2.9	-2.6	-3.2	-1.9
Age at last live birth	5.5	7.9	16.3	-2.9	-3.1	-3.2	-2.0	-2.5	1.8	3.3	2.6	3.1	-4.0	-2.1	3.4	2.6	3.0	2.9	3.1
Multivitamins +/- minerals	5.3	6.7	11.1	-3.2	-1.9	-3.1	-2.0	-0.5	3.3	3.2	2.9	2.4	-2.7	-2.6	3.0	2.7	2.5	3.2	1.9
Systolic Blood Pressure	4.8	24.1	46.4	6.2	3.4	5.5	5.0	2.3	-5.3	-5.8	-4.3	-6.8	4.8	4.8	-5.7	-3.7	-5.6	-6.0	-3.3
Ever used hormone-replacement therapy (HRT)	4.8	6.1	11.3	-2.8	-3.2	-2.8	-2.3	-3.4	3.0	2.5	2.1	2.2	-1.8	-1.9	2.8	1.3	3.2	2.5	1.7
Age at first live birth	4.5	7.9	15.5	-2.7	-2.5	-3.0	-2.2	-1.5	2.1	3.4	3.3	3.7	-3.9	-2.0	3.4	2.6	3.0	3.1	2.8
Systolic blood pressure, automated reading	4.4	12.9	24.7	4.9	2.4	4.4	3.1	2.1	-3.3	-4.1	-2.7	-5.0	4.8	2.9	-4.2	-2.0	-4.4	-4.2	-2.7
Diastolic blood pressure, automated reading	4.2	13.1	24.6	5.0	2.8	4.8	3.3	2.6	-3.3	-4.1	-3.1	-4.0	4.3	2.8	-4.3	-1.4	-4.7	-3.9	-3.6
Vitamin and mineral supplements	4.1	5.6	9.7	2.8	2.0	2.5	2.4	0.5	-3.1	-2.9	-2.4	-2.1	2.1	2.6	-2.7	-3.0	-2.2	-2.7	-1.7
Medication: Blood pressure	3.8	7.2	12.3	2.9	1.9	3.0	2.2	0.7	-2.7	-3.3	-3.0	-3.5	3.2	2.1	-3.4	-2.5	-3.4	-3.3	-1.4
Illnesses of father: None of the above (group 1)	3.7	4.6	8.6	-2.9	-2.5	-2.7	-2.6	-1.1	1.7	2.5	2.2	1.5	-1.8	-2.0	2.6	1.9	2.5	2.0	2.3
Illnesses of siblings	3.6	5.1	12.3	-3.5	-1.4	-2.5	-2.5	-0.5	2.2	2.8	1.8	2.7	-1.9	-1.5	2.7	1.9	2.7	2.5	2.5
Illnesses of mother	3.5	4.3	8.7	-2.8	-1.5	-2.6	-2.0	-1.2	2.2	2.2	1.4	2.4	-2.6	-0.7	2.3	0.6	2.7	2.1	2.9
Length of working week for main job	3.5	3.9	7.3	1.4	1.7	1.8	2.1	1.1	-1.2	-2.2	-2.5	-2.6	2.0	1.4	-2.5	-1.9	-2.3	-2.7	-2.1
Mean Putamen Volume	3.4	3.9	15.4	-2.5	-1.4	-1.8	-1.1	-1.7	0.9	2.1	1.7	2.4	-3.9	-0.6	2.1	0.6	2.4	2.6	2.0
Number of treatments/medications taken	3.3	5.9	10.6	3.3	1.5	2.7	2.2	1.2	-1.8	-3.2	-1.3	-3.1	3.0	2.8	-3.0	-2.7	-2.4	-2.5	-2.1
High blood pressure	3.3	9.1	15.4	3.9	1.6	3.5	2.7	-0.0	-2.7	-3.8	-3.1	-3.7	3.1	2.8	-3.7	-3.0	-3.5	-3.9	-1.9
Mouth/teeth dental problems: Loose teeth	3.2	3.8	13.5	-1.8	-3.1	-2.0	-2.1	-3.7	1.5	1.4	1.4	0.9	-1.5	-0.5	1.9	-1.0	2.5	1.2	3.0
Hypertension (Self-reported)	3.2	9.0	15.1	3.8	1.7	3.4	2.6	0.1	-2.8	-3.8	-3.1	-3.9	3.0	2.7	-3.7	-3.0	-3.5	-3.9	-1.7
Supplements: Zinc	3.1	3.4	7.6	-2.6	-1.3	-1.7	-2.4	-1.5	2.1	2.1	0.9	1.6	-2.1	-1.0	2.0	1.0	2.1	1.9	2.8
Relative age voice broke	3.1	4.8	9.2	-3.0	-1.5	-1.9	-2.7	-1.3	1.8	2.5	2.2	2.2	-2.6	-2.4	2.6	1.7	2.4	2.4	2.3
Medication for cholesterol	3.0	4.5	7.3	-2.7	-1.0	-2.3	-2.1	0.4	2.2	2.7	2.3	2.7	-2.4	-2.1	2.6	1.5	2.4	2.3	2.0
Average weekly champagne plus white wine intake	3.0	4.1	7.4	-2.7	-1.2	-2.2	-2.2	-0.3	1.8	2.5	1.5	2.1	-2.0	-2.2	2.5	2.2	2.4	2.7	1.3
Reaction Time	2.8	5.4	9.3	2.5	2.4	2.6	2.8	2.0	-2.0	-2.7	-3.0	-2.1	2.5	1.1	-2.7	-1.4	-2.8	-1.9	-3.1
Ever had hysterectomy (womb removed)	2.8	3.2	6.3	2.4	1.6	2.5	2.5	1.3	-2.0	-2.0	-1.5	-1.5	1.6	1.2	-2.1	-0.5	-2.1	-1.1	-2.2
Supplements: Vitamin C	2.8	3.3	10.0	-2.0	-2.0	-1.1	-2.5	-1.4	3.2	2.1	1.0	2.0	-0.6	-2.1	1.7	2.5	1.2	1.6	1.3
Height	2.7	52.0	104.0	-8.2	-7.1	-9.3	-10.2	-7.0	8.1	7.7	5.5	6.2	-3.2	-6.0	8.6	2.9	8.9	6.3	9.2
Qualifications: College or University degree	2.7	8.6	20.4	-4.4	-1.4	-3.7	-3.1	0.0	2.4	3.6	1.6	2.4	-3.1	-3.2	3.6	2.3	3.1	2.5	4.5
Eye problems/disorders: None of the above	2.7	3.1	8.0	-2.1	-2.2	-1.4	-2.8	-0.3	0.8	2.0	1.2	2.3	-1.3	-2.1	1.8	1.9	1.5	2.2	1.5
Overall health rating	2.7	5.8	16.2	2.6	1.6	3.1	1.5	0.8	-0.8	-2.9	-2.7	-2.5	4.0	1.5	-2.9	-2.0	-2.8	-3.4	-2.1
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.6	8.5	-2.7	-2.0	-2.9	-2.8	-1.6	2.8	2.8	2.3	2.8	-2.4	-1.5	2.9	1.8	2.7	2.5	1.9
Gout (self-reported)	2.6	3.6	7.2	2.5	1.0	2.5	2.3	0.1	-1.3	-2.2	-2.3	-1.9	1.8	1.6	-2.5	-1.0	-2.4	-0.9	-2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.6	3.1	5.1	-1.9	-1.9	-1.7	-2.2	-1.4	1.5	2.0	1.7	1.9	-1.6	-1.9	2.1	1.5	1.9	1.7	1.7
Type 2 Diabetes (T2D) (2018)	2.5	4.7	13.1	2.6	0.9	2.0	0.7	-0.3	-2.2	-2.6	-2.6	-3.2	3.6	1.8	-2.3	-2.2	-2.0	-2.8	-1.1
Waist Hip Ratio (WHR)	2.3	10.5	32.3	-3.2	-2.9	-2.5	-1.9	-0.5	2.5	3.7	4.6	3.2	-5.7	-2.5	3.6	4.0	3.0	4.2	1.9
Hand grip strength (right)	2.3	6.3	16.8	-2.9	-2.2	-4.1	-3.5	-2.5	2.7	2.6	1.1	2.3	-1.2	-1.3	3.2	0.9	3.4	1.5	3.2
Ever had prostate specific antigen (PSA) test	2.3	2.6	6.0	-1.8	-1.0	-1.2	-1.6	0.7	1.2	2.0	1.6	2.2	-2.0	-2.5	1.6	2.2	0.7	1.8	1.5
Cholesterol lowering medication	2.3	3.4	5.9	2.4	0.9	2.4	1.7	0.7	-2.0	-2.2	-2.2	-2.1	1.9	1.1	-2.3	-0.8	-2.4	-1.5	-2.2
Age at First Birth	2.2	3.2	9.6	-2.3	-1.2	-1.9	-2.2	-1.4	0.5	2.0	1.4	1.7	-2.1	-1.4	2.3	0.6	2.4	0.9	3.1
Hair/balding pattern: Pattern 4	2.2	5.3	9.8	2.6	1.6	2.7	2.2	0.7	-2.0	-2.8	-2.5	-3.1	2.3	1.9	-2.7	-2.1	-2.6	-2.8	-2.0
Commuting to job workplace: Cycle	2.2	2.6	8.5	-2.1	-0.6	-1.8	-1.7	-0.1	0.2	1.9	1.5	0.9	-2.9	-1.2	2.0	0.7	1.8	1.6	2.7
Hand grip strength (left)	2.1	5.5	13.4	-2.7	-2.1	-3.7	-3.1	-2.6	1.9	2.4	1.0	2.3	-1.4	-1.2	3.0	0.6	3.3	1.6	3.1
Body mass index (BMI)	2.1	9.1	42.1	3.3	1.5	3.5	0.8	0.1	-0.7	-3.5	-2.8	-3.3	6.5	1.1	-3.5	-2.3	-3.6	-3.9	-2.9
Long-standing illness, disability or infirmity	2.1	3.2	8.4	2.2	1.4	2.5	1.4	1.7	-0.6	-2.1	-1.4	-1.6	2.9	1.1	-2.1	-1.4	-2.2	-2.0	-1.3
Cardiovascular Disease	2.0	6.8	12.2	3.5	1.1	2.5	2.3	-0.3	-2.7	-3.3	-2.8	-3.5	2.4	2.7	-3.1	-2.8	-2.9	-3.4	-1.3
Leg fat percentage (right)	2.0	7.1	27.0	3.1	1.5	3.9	0.8	0.9	-1.2	-3.0	-2.4	-2.5	5.2	0.5	-3.1	-1.6	-3.4	-3.4	-2.8
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	4.0	-1.8	-1.2	-1.5	-1.8	-1.0	1.1	1.7	1.5	2.0	-1.5	-1.4	1.8	1.7	1.6	1.9	1.4
Health satisfaction	2.0	2.6	7.3	1.9	1.3	2.1	0.7	0.4	-0.6	-2.1	-1.1	-1.3	2.7	1.4	-2.0	-1.8	-1.6	-2.2	-1.8
Comparative height size at age 10	2.0	11.0	27.4	-3.4	-4.2	-4.1	-5.2	-3.7	3.7	3.3	2.1	3.0	-0.2	-2.4	3.8	1.9	3.7	2.6	4.1
Heart disease (siblings)	2.0	2.4	5.3	2.3	0.9	1.2	1.2	0.3	-1.1	-1.8	-1.5	-2.0	1.9	1.4	-1.9	-1.3	-1.8	-1.6	-2.1
Smoking Status	1.9	4.5	7.8	-2.3	-2.3	-2.8	-2.2	-2.4	2.1	2.4	1.9	1.1	-2.4	-1.6	2.5	1.5	2.5	2.4	2.2
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	5.2	1.2	1.2	0.6	1.1	-0.5	-0.8	-1.7	-1.9	-2.1	1.9	1.1	-1.5	-2.3	-1.1	-1.8	-1.5
Sitting height	1.9	13.5	27.0	-3.9	-3.4	-4.2	-5.2	-2.2	4.8	4.3	3.3	3.3	-1.9	-3.7	4.4	3.4	3.8	3.8	3.5
Standing height	1.9	19.0	35.6	-5.1	-4.2	-5.6	-6.0	-3.9	4.5	4.9	3.3	3.8	-3.0	-3.3	5.3	2.7	5.2	3.9	5.3
Breastfed as a baby	1.9	2.3	4.9	-1.2	-1.3	-1.4	-2.1	-0.4	1.7	1.9	1.7	1.8	-0.8	-2.2	1.9	1.7	1.5	1.7	0.9
Wheeze or whistling in the chest in last year	1.9	3.4	6.4	2.5	1.1	1.8	1.3	1.7	-0.7	-2.1	-1.3	-2.4	2.5	1.8	-2.1	-1.3	-2.1	-2.1	-2.3
Medication: Blood pressure	1.9	3.3	5.8	2.4	1.4	2.4	1.9	1.1	-1.7	-2.2	-1.2	-2.1	1.2	1.9	-2.3	-1.7	-2.2	-2.1	-1.2
Mean time to correctly identify matches	1.9	3.7	7.1	2.1	1.4	1.9	2.4	1.5	-1.6	-2.2	-2.7	-2.0	2.2	0.7	-2.2	-0.9	-2.4	-1.7	-2.4
Illnesses of siblings: Diabetes	1.9	2.3	5.7	2.1	1.3	1.9	2.1	2.0	-1.7	-1.5	-1.3	-1.2	1.1	0.4	-1.4	-0.5	-1.5	-0.9	-2.4
Medication: Atorvastatin	1.9	2.4	6.5	1.8	1.5	2.4	1.9	2.4	-2.5	-1.3	-1.2	-1.1	0.3	0.6	-1.6	-0.1	-2.0	-0.8	-1.1
Average weekly beer plus cider intake	1.9	2.7	7.5	2.2	1.8	2.1	1.5	0.6	-2.0	-1.8	-0.4	-1.1	1.1	1.4	-1.9	-1.8	-1.6	-1.5	-2.7
Vascular/heart problems diagnosed by doctor	1.9	5.1	10.2	-3.2	-0.9	-2.9	-2.4	-0.3	2.1	2.9	1.8	2.7	-2.3	-2.0	2.8	2.1	2.7	2.7	1.6
Schizophrenia (2018)	1.8	3.8	8.2	1.8	2.3	1.8	2.9	2.3	-2.1	-2.0	-2.3	-1.3	0.8	2.1	-2.2	-1.4	-2.0	-1.7	-2.2
Body Mass Index (BMI) (2010)	1.8	2.4	10.3	1.5	0.9	2.0	0.3	0.0	-0.6	-1.8	-1.9	-1.8	3.2	0.4	-1.8	-1.1	-2.1	-2.0	-0.8
BMI	1.8	10.6	46.5	3.6	2.2	3.5	0.6	0.3	-1.6	-3.8	-2.9	-3.5	6.8	1.8	-3.8	-2.9	-3.6	-4.4	-2.5
Medication: Metformin	1.8	2.5	7.0	2.0	0.4	1.6	1.1	-0.7	-1.0	-1.7	-2.1	-2.6	2.1	1.5	-1.6	-1.6	-1.4	-2.0	-1.2
Medication: Ramipril	1.8	2.3	5.8	1.9	0.4	2.0	1.6	0.0	-1.2	-1.7	-1.5	-2.1	2.4	1.2	-1.7	-0.4	-1.7	-1.5	-1.3
Arm fat percentage (right)	1.8	7.0	36.1	2.8	1.4	3.6	0.1	0.1	-0.5	-3.0	-2.3	-2.2	6.0	0.6	-3.1	-2.0	-3.2	-3.3	-2.4
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.1	5.1	1.1	1.4	2.1	1.0	1.3	-0.1	-1.2	-2.2	-0.8	2.3	-0.6	-1.5	0.5	-2.1	-1.1	-2.1
Loud music exposure frequency	1.8	2.0	6.2	-0.6	-2.1	-1.2	-1.3	-2.0	1.2	1.1	2.5	1.6	0.2	-1.0	1.4	0.7	1.7	1.5	1.4
Guilty feelings	1.8	2.7	6.6	-2.2	-0.9	-2.4	-2.1	-2.2	2.6	1.1	1.2	0.9	-0.6	-1.0	1.4	-1.7	1.9	-0.4	2.0
Leg fat percentage (left)	1.8	6.7	24.5	3.0	1.7	3.8	0.7	0.9	-1.2	-2.9	-2.3	-2.4	5.0	0.4	-3.0	-1.7	-3.3	-3.2	-2.8
Type 2 Diabetes (T2D) (2012)	1.7	2.0	7.3	-1.7	-1.4	-2.7	-1.5	-1.3	1.2	1.6	0.3	0.9	-0.5	-1.0	1.8	0.6	1.9	1.1	1.7
Stomach or abdominal pain in last month	1.7	2.1	5.8	0.9	0.7	1.0	0.7	0.0	-0.0	-1.7	-1.8	-2.2	2.4	1.7	-1.3	-2.1	-0.7	-2.4	-0.5
Chronic bronchitis/emphysema (father)	1.7	1.9	4.1	1.9	0.6	2.0	2.0	0.4	-0.6	-1.5	-0.7	-1.1	1.5	1.3	-1.8	-0.8	-1.8	-1.3	-1.9
Body fat percentage	1.7	6.8	30.6	2.8	1.3	3.7	0.1	0.1	-0.9	-3.0	-2.5	-2.1	5.5	0.5	-2.9	-2.3	-3.1	-3.5	-2.3
Commuting to job workplace: Public transport	1.7	2.0	5.8	-1.6	-0.6	-0.7	-0.7	0.9	1.8	1.8	1.4	2.3	-1.5	-2.4	1.2	2.3	0.3	1.3	0.6
Medication: Bendroflumethiazide	1.7	2.5	6.3	2.0	0.3	1.3	0.8	-1.2	-1.4	-2.1	-0.8	-1.9	2.2	2.0	-1.8	-2.5	-1.3	-1.9	-0.7
Bipolar Disorder or Schizophrenia	1.6	4.0	11.4	1.5	2.6	2.0	3.4	3.1	-2.3	-1.6	-1.9	-0.6	-0.4	1.9	-2.1	-0.2	-2.3	-0.9	-2.8
Pack years adult smoking proportion	1.6	2.4	12.1	1.4	2.3	2.2	-0.0	3.5	-1.4	-1.4	-0.7	-1.0	1.9	0.0	-1.5	-0.4	-2.1	-1.1	-0.1
Bilateral oophorectomy (both ovaries removed)	1.6	1.9	4.2	1.5	0.7	1.8	1.8	0.2	-1.4	-1.5	-2.0	-0.8	1.3	1.1	-1.8	-0.8	-1.8	-0.7	-1.8
Lung cancer (father)	1.6	1.9	3.9	-1.4	-1.9	-2.0	-1.8	-1.3	0.3	1.4	1.5	1.4	-1.5	-0.6	1.6	-0.1	2.0	1.6	0.8
Arm fat percentage (left)	1.6	6.4	33.6	2.5	1.5	3.5	-0.1	0.4	-0.3	-2.8	-2.3	-2.0	5.8	0.3	-2.9	-1.9	-3.1	-3.1	-2.3
Average weekly spirits intake	1.5	1.8	5.0	1.4	0.4	1.4	0.7	0.4	-1.1	-1.4	-1.3	-1.4	2.0	0.7	-1.7	-0.7	-2.0	-2.2	-1.6
Nervous feelings	1.5	2.7	10.2	1.7	1.5	1.4	1.5	-1.2	-0.2	-2.0	-1.2	-1.6	1.5	2.1	-1.9	-3.2	-1.2	-2.2	-1.0
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	5.4	-2.2	-1.5	-1.7	-1.6	-1.0	2.1	2.0	0.5	1.6	-0.7	-1.9	1.8	2.3	1.4	1.1	0.7
Exposure to tobacco smoke outside home	1.5	2.0	7.6	-0.4	-2.1	-0.6	-1.3	-0.7	0.8	1.3	2.8	1.8	-0.0	-1.8	1.3	2.4	0.7	1.5	-0.0
Medication: Allopurinol	1.5	2.0	4.0	1.9	1.2	2.0	1.3	-0.1	-0.8	-1.8	-1.8	-1.1	1.5	1.5	-1.9	-1.3	-1.7	-0.6	-1.6
Leg fat mass (right)	1.5	5.9	33.4	2.7	1.0	3.0	-0.3	-0.1	-0.5	-2.7	-2.2	-2.3	5.8	0.5	-2.6	-1.9	-2.7	-3.2	-2.1
Osteoarthritis (self-reported)	1.5	2.0	6.5	1.5	0.7	1.1	0.6	-0.9	-0.8	-1.8	-1.5	-1.9	2.5	1.8	-1.5	-1.9	-0.9	-1.2	-0.6
Chronotype (morning person)	1.4	3.3	8.2	-2.6	-1.0	-1.7	-2.9	-0.7	2.4	1.8	2.1	1.9	-0.4	-2.0	2.1	0.5	2.3	1.2	2.0
Trunk fat percentage	1.4	5.5	27.4	2.4	0.9	3.3	-0.4	-0.3	-0.7	-2.6	-2.4	-1.8	5.2	0.4	-2.5	-2.3	-2.5	-3.2	-1.8
Supplements: Glucosamine	1.4	1.9	8.2	-0.7	-0.9	-1.1	-0.7	-0.6	1.4	1.5	2.9	1.3	-1.9	-0.2	1.2	1.4	1.3	2.3	0.0
High blood pressure (mother)	1.4	2.0	3.9	1.3	1.1	1.6	1.4	0.0	-1.3	-1.7	-1.7	-1.3	1.3	1.2	-1.7	-1.6	-1.6	-2.0	-1.6
High blood pressure (siblings)	1.4	2.1	4.6	2.1	1.3	1.7	0.8	0.3	-1.3	-1.8	-1.1	-1.8	1.5	0.6	-1.6	-1.8	-1.6	-2.1	-0.7
Medication: Lisinopril	1.4	1.9	4.0	1.9	2.0	1.5	1.5	1.8	-1.8	-1.6	-0.9	-0.8	1.0	0.8	-1.5	-0.8	-1.8	-1.3	-0.1
Forced expiratory volume in 1-second (FEV1)	1.3	4.4	12.0	-2.9	-1.5	-2.6	-2.8	-3.3	1.9	1.6	0.3	1.5	-0.7	-0.5	2.3	-0.6	3.1	0.8	3.5
Birth weight	1.3	2.7	11.1	-2.1	-1.4	-1.4	-3.3	-2.3	1.3	1.2	0.6	1.1	1.1	-1.9	1.5	-0.6	1.6	0.5	2.6
Emphysema/chronic bronchitis	1.3	1.5	5.4	1.3	0.0	1.4	0.8	0.1	-0.4	-1.5	-0.7	-1.1	2.3	0.6	-1.5	-1.1	-1.5	-1.8	-1.4
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	2.8	-1.7	-0.1	-1.2	-1.3	0.6	1.5	1.6	1.3	1.6	-1.5	-1.5	1.4	1.2	1.1	1.7	0.9
Illnesses of father: Heart disease	1.3	1.8	5.9	1.7	0.8	2.0	1.3	0.6	-0.1	-1.5	-1.6	-0.1	2.4	0.4	-1.5	-1.0	-1.6	-1.3	-1.7
Leg fat mass (left)	1.3	5.2	30.0	2.4	1.0	2.7	-0.5	-0.3	-0.4	-2.5	-2.0	-2.2	5.5	0.4	-2.4	-2.0	-2.5	-3.0	-1.9
Schizophrenia vs Biploar Disorder	1.2	1.6	5.3	1.3	0.7	0.7	1.3	-0.7	-1.4	-1.4	-1.5	-1.5	1.2	1.5	-1.2	-2.3	-0.5	-1.8	-0.2
Schizophrenia (2014)	1.2	2.5	6.8	1.5	2.1	1.5	2.6	2.0	-1.8	-1.6	-1.6	-1.0	0.1	1.7	-1.7	-0.7	-1.6	-1.2	-1.9
Serious illness, injury or assault to yourself	1.2	1.4	2.7	1.6	0.1	1.5	1.0	-0.5	-0.9	-1.7	-0.7	-1.3	1.2	1.4	-1.5	-1.4	-1.2	-1.6	-0.9
Forced vital capacity (FVC)	1.2	4.5	11.3	-2.6	-1.9	-2.7	-2.9	-3.4	2.1	1.9	0.8	1.5	-0.8	-0.4	2.5	0.0	3.3	1.0	3.2
Depression (self-reported)	1.2	1.5	5.9	-1.3	-0.3	-1.3	-1.7	-0.6	2.2	1.1	2.4	0.9	-0.4	-0.6	1.2	0.0	1.5	0.5	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.9	13.1	-2.7	-1.8	-2.1	-3.1	-3.6	1.6	1.4	-0.1	1.0	-0.3	-0.7	2.1	-0.5	2.8	0.4	3.3
Medication: Seretide 50 evohaler	1.2	1.4	5.0	-0.9	-1.5	-1.0	-0.7	0.1	1.8	1.3	2.2	1.2	-0.6	-1.2	1.2	1.5	0.9	1.1	0.5
Family relationship satisfaction	1.2	1.5	9.6	0.0	-2.3	-1.2	-1.3	-3.1	0.8	0.6	0.9	0.8	-0.1	-0.5	1.0	0.3	1.0	0.7	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	10.0	0.5	0.2	0.6	1.2	-2.5	-0.9	-1.8	-1.6	-1.7	1.4	2.6	-1.6	-3.2	-0.3	-1.8	-0.1
Wears glasses or contact lenses	1.2	1.4	4.9	-1.3	-1.4	-0.3	-1.1	-0.9	2.2	1.2	1.2	1.6	0.1	-1.7	1.0	0.6	0.8	1.0	1.4
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.3	1.5	0.5	1.8	1.2	0.5	-1.2	-1.4	-1.0	-0.9	1.3	0.4	-1.4	-0.3	-1.7	-1.4	-1.4
Noisy workplace	1.1	1.3	3.3	1.7	0.1	1.2	1.2	-0.7	-1.0	-1.5	-1.1	-0.6	0.9	1.2	-1.5	-1.4	-1.1	-0.9	-1.8
Arm fat mass (right)	1.1	4.4	29.7	2.0	0.5	2.3	-0.8	-0.7	0.2	-2.2	-1.8	-1.9	5.5	0.2	-2.2	-1.6	-2.3	-2.7	-1.7
Forced vital capacity (FVC), Best measure	1.1	4.2	15.3	-2.4	-2.2	-2.3	-3.1	-3.9	1.7	1.5	0.3	0.8	-0.3	-0.5	2.2	-0.2	2.9	0.4	3.3
Comparative body size at age 10	1.1	3.0	9.5	-2.4	-0.5	-2.0	-3.1	-1.4	2.5	1.8	0.2	1.4	0.7	-2.5	1.9	0.8	1.7	1.1	1.6
Number of full brothers	1.1	1.4	4.5	1.8	0.5	1.3	2.1	-0.2	-0.5	-1.1	-0.6	-0.8	1.4	0.6	-1.4	-0.3	-1.6	-0.9	-1.8
Shortness of breath walking on level ground	1.1	1.3	2.3	1.3	0.4	1.3	1.5	-0.6	0.1	-1.4	0.1	-0.8	1.3	1.1	-1.5	-1.5	-1.2	-1.5	-1.4
Migraine (self-reported)	1.1	1.4	7.7	-0.8	-0.5	-1.6	-0.1	-1.3	-0.9	0.7	0.5	0.5	-2.8	0.8	1.1	-0.6	1.7	0.2	2.1
Whole body fat mass	1.1	4.5	29.4	2.0	0.4	2.4	-0.9	-0.9	0.0	-2.2	-2.0	-1.8	5.4	0.2	-2.1	-1.9	-2.1	-2.9	-1.5
Average weekly red wine intake	1.1	1.6	4.0	-1.8	-1.6	-0.7	-0.6	-0.7	0.9	1.5	0.6	1.2	-1.6	-1.4	1.5	0.8	1.4	1.0	2.0
Arm fat mass (left)	1.1	4.7	31.5	2.0	0.7	2.4	-0.7	-0.6	0.3	-2.3	-1.9	-1.9	5.6	0.2	-2.2	-1.7	-2.4	-2.8	-1.7
Unable to work because of sickness or disability	1.1	1.4	3.3	1.8	0.2	1.3	1.7	0.3	-1.1	-1.4	-0.8	-1.2	1.3	0.9	-1.4	-0.7	-1.4	-0.9	-1.6
Basal cell carcinoma (self-reported)	1.1	1.3	3.5	0.8	0.5	0.4	0.5	-0.7	-1.3	-1.2	-1.8	-1.5	1.3	1.5	-1.1	-1.9	-0.6	-1.4	0.6
Pack years of smoking	1.1	1.7	9.5	1.1	1.8	1.8	-0.4	3.1	-1.0	-1.0	-0.3	-0.8	1.8	-0.3	-1.1	0.0	-1.6	-0.8	-0.2
Bipolar Disorder (2011)	1.0	1.0	4.5	-0.9	0.2	-1.0	0.2	1.2	-0.7	0.8	0.3	1.7	-2.1	-0.4	0.8	0.9	0.7	1.4	0.5
Maternal smoking around birth	1.0	1.5	3.1	-1.3	-1.5	-0.1	-1.7	-1.1	1.4	1.2	1.3	1.8	-1.5	-1.6	1.0	1.1	0.6	1.2	0.6
Pain all over the body in last month	1.0	1.1	2.2	0.4	1.4	1.1	1.1	0.4	-1.5	-1.2	-1.0	-1.1	0.8	0.9	-1.3	-1.1	-1.3	-1.4	-0.8
Alcohol intake frequency.	1.0	2.4	10.7	1.8	0.6	1.7	0.9	0.9	0.1	-1.6	-1.5	-1.1	3.3	0.1	-1.7	-0.2	-2.2	-1.9	-2.2
Diabetes diagnosed by doctor	1.0	1.6	6.8	1.3	-0.5	1.1	-0.1	-1.3	-0.5	-1.3	-1.6	-2.1	2.6	0.6	-1.1	-1.3	-1.0	-1.8	-0.3
Ever taken oral contraceptive pill	1.0	1.1	2.6	-0.9	-0.0	-1.0	-1.2	-0.2	1.1	1.3	0.9	1.0	-1.4	-0.5	1.3	0.9	1.1	1.6	1.5
Alcohol drinker status: Previous	1.0	1.1	5.1	-0.7	-0.2	0.2	-1.0	0.8	2.1	1.0	0.5	0.5	0.8	-2.3	0.6	1.9	-0.1	0.3	-0.6
Intelligence (Savage-Jansen 2018)	0.9	2.7	9.8	-2.2	-0.2	-1.7	-1.5	1.3	0.7	2.0	-0.4	1.6	-1.5	-3.1	2.0	1.9	1.3	1.6	1.5
Prostate Cancer	0.9	1.3	3.4	-1.5	0.1	-1.3	-1.1	0.6	1.3	1.2	0.7	1.0	-1.8	-0.1	1.3	0.1	1.6	1.8	1.2
Coronary Artery Disease (CAD)	0.9	1.1	7.3	-0.3	-1.5	0.3	-0.6	-0.5	1.1	0.9	1.4	1.1	-0.4	-0.8	1.1	2.7	0.6	0.8	0.1
Sensitivity / hurt feelings	0.9	1.6	4.7	1.6	1.1	1.4	0.8	0.0	-0.3	-1.6	-1.6	-0.7	2.2	1.0	-1.4	-1.4	-1.1	-1.6	-1.1
Trunk fat mass	0.9	3.7	27.0	1.7	0.2	2.2	-1.4	-1.1	0.2	-1.9	-1.6	-1.3	5.2	-0.1	-1.7	-1.8	-1.8	-2.5	-1.1
Hip circumference	0.9	3.9	26.9	1.3	0.5	2.3	-1.1	-0.3	0.5	-1.8	-2.3	-1.8	5.2	-0.8	-1.9	-0.9	-2.4	-2.5	-1.1
Qualifications: A levels/AS levels or equivalent	0.9	2.0	5.3	-2.2	-0.6	-1.8	-1.2	0.6	1.3	1.9	0.0	1.1	-1.4	-1.9	1.7	2.3	1.1	0.8	1.5
Birth weight of first child	0.9	1.6	4.6	-2.1	-1.5	-1.4	-2.0	-1.2	1.6	1.4	0.2	0.7	-0.3	-1.6	1.3	0.3	1.2	0.9	1.2
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	3.2	-1.6	-1.1	-1.8	-1.3	-1.3	1.1	1.4	-0.0	1.3	-0.5	-1.5	1.5	1.2	1.3	1.1	1.0
Worry too long after embarrassment	0.9	1.6	5.3	-1.6	-0.8	-1.1	-1.8	-0.8	1.7	1.1	1.2	0.9	-0.9	-1.3	1.3	-0.8	1.4	0.2	2.3
Heart disease (mother)	0.9	1.1	2.8	1.6	0.3	1.3	0.7	0.2	-0.7	-1.0	-1.4	-1.3	1.7	-0.2	-0.9	-0.1	-1.3	-1.6	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.0	2.3	1.2	0.1	0.8	0.9	-0.5	-0.1	-1.1	-1.5	-1.1	1.3	1.1	-1.3	-1.0	-1.3	-1.1	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	5.0	-0.6	-1.3	-1.3	-1.0	-2.2	0.2	0.3	1.1	1.0	-0.6	0.3	0.5	-1.6	1.3	0.5	0.2
Number of self-reported non-cancer illnesses	0.9	1.6	5.1	2.2	-0.5	1.2	0.9	0.0	-0.6	-1.6	-0.3	-1.4	1.4	2.3	-1.5	-1.5	-1.0	-1.1	-0.9
Eye problems/disorders: Glaucoma	0.9	1.1	4.5	0.4	2.1	1.0	1.7	1.8	-0.6	-0.8	-1.0	-1.0	-0.5	1.2	-0.8	-0.2	-0.9	-0.4	-0.1
Bipolar Disorder (2018)	0.8	1.2	4.2	0.2	1.4	0.9	1.9	2.1	-1.0	-0.1	-0.2	0.6	-1.5	0.2	-0.6	1.4	-1.1	0.6	-1.7
Alzheimer’s Disease (in mother)	0.8	0.9	1.9	1.1	1.3	0.8	1.4	1.1	-1.4	-0.9	-1.3	-0.7	0.3	0.3	-0.9	-0.8	-1.1	-0.7	-0.7
Fasting Glucose	0.8	0.9	2.5	1.1	0.4	1.3	0.1	0.0	-1.1	-1.1	-1.0	-1.6	1.0	0.4	-1.0	-0.7	-1.2	-1.4	-0.2
Lupus	0.8	1.2	3.0	-1.5	-1.0	-1.1	-1.4	-1.1	1.4	1.1	0.0	0.8	-1.2	-0.6	1.1	1.0	0.8	0.6	1.7
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	3.5	1.2	1.7	1.9	1.4	1.2	-1.1	-1.3	-1.0	-0.8	1.2	1.4	-1.6	-0.6	-1.4	-1.8	-1.6
Hayfever, allergic rhinitis or eczema	0.8	1.8	9.9	-0.6	-1.8	-1.6	0.2	-1.5	-0.0	1.1	1.5	1.3	-3.1	0.5	1.3	0.0	1.8	1.2	0.5
Alcohol usually taken with meals	0.8	1.3	2.7	-1.2	-1.6	-0.9	-0.2	-1.1	0.6	1.3	0.8	1.4	-1.5	-0.5	1.3	1.2	1.4	1.5	1.4
Diabetes (self-reported)	0.8	1.3	3.8	1.2	-0.5	0.8	-0.0	-1.6	-0.9	-1.2	-1.6	-1.7	1.9	0.8	-0.9	-1.4	-0.6	-1.4	0.1
Trunk predicted mass	0.8	4.4	12.7	-1.8	-2.5	-2.7	-3.4	-2.6	3.6	1.8	1.8	0.9	1.4	-1.8	1.9	1.6	1.6	1.2	2.0
Peak expiratory flow (PEF)	0.8	1.9	5.1	-2.0	-1.1	-1.4	-1.8	-2.3	1.7	1.0	0.1	1.5	-0.3	-0.6	1.4	-0.3	2.0	0.3	2.0
Back pain experienced in last month	0.8	1.2	3.3	-0.7	-1.7	-0.4	-1.4	-0.3	1.5	1.0	1.8	0.9	-0.7	-1.0	1.2	0.8	1.3	0.9	0.9
Medication: Aspirin	0.8	1.1	3.3	1.1	0.0	1.2	1.2	0.8	-0.9	-1.1	-0.4	-1.2	1.0	0.6	-1.5	0.2	-1.8	-1.1	-1.4
High cholesterol (Self-reported)	0.8	1.4	4.7	1.5	0.7	2.2	1.1	1.5	-1.4	-1.2	-1.1	-1.1	0.5	0.3	-1.4	0.0	-1.8	-0.7	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.3	-0.2	-1.1	-0.5	-1.8	-1.7	1.4	0.3	0.6	1.1	1.0	-0.5	0.6	-0.8	0.8	0.2	1.6
Alzheimer’s Disease (including proxy)	0.7	1.0	2.6	1.5	1.2	1.4	1.0	0.9	-0.6	-1.2	-1.6	-0.6	0.8	0.7	-1.1	-0.8	-1.4	-0.5	0.1
HbA1C	0.7	0.7	2.4	-1.0	-0.3	-0.7	-1.1	-0.3	1.5	0.9	0.9	-0.1	-1.2	-1.2	0.8	0.4	0.5	0.7	1.1
Trunk fat-free mass	0.7	4.2	11.8	-1.8	-2.5	-2.6	-3.3	-2.6	3.4	1.8	1.8	0.9	1.4	-1.7	1.9	1.6	1.6	1.2	2.0
Time employed in main current job	0.7	0.8	2.4	0.4	0.4	0.3	0.7	-0.5	-1.1	-1.0	-1.4	-1.6	0.4	1.0	-0.8	-1.5	-0.5	-1.3	-0.8
Prospective memory result	0.7	0.8	2.2	-0.6	-1.5	-1.3	-1.1	-0.9	0.3	1.0	0.2	0.8	-1.0	-0.6	1.2	0.2	1.3	0.8	0.7
Pulse wave reflection index	0.7	0.8	2.9	0.9	0.6	0.0	0.5	-0.2	-1.3	-1.0	-0.9	-1.7	0.4	1.3	-0.6	-1.7	-0.1	-1.1	0.0
Ever highly irritable/argumentative for 2 days	0.7	0.9	3.4	1.2	-0.0	0.5	0.8	-1.1	-0.6	-1.1	0.2	-0.3	0.6	1.5	-0.7	-1.8	0.1	-1.0	-1.5
Blood clot in the leg (DVT)	0.7	0.9	2.8	-1.3	-1.2	-1.0	-0.4	-0.8	1.7	1.1	0.7	0.9	-0.9	-0.7	0.8	1.0	0.7	1.4	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	4.0	0.7	-1.3	0.3	0.8	-0.7	1.4	0.3	2.0	0.8	-0.5	0.1	0.1	1.6	-0.2	0.8	-1.0
Commuting to job workplace: Car/motor vehicle	0.7	0.9	1.9	1.3	0.5	0.3	1.1	0.4	-0.5	-1.1	-0.9	-1.1	1.4	1.2	-0.8	-0.6	-0.6	-1.1	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.2	0.5	1.1	1.1	1.1	1.5	-1.1	-0.6	-0.8	-0.9	-0.6	0.8	-0.9	-0.2	-1.2	-0.5	0.2
Mother’s age at death	0.7	0.8	5.0	-1.0	-0.3	-1.3	0.0	0.3	-1.1	0.8	0.1	0.3	-2.2	0.6	0.9	0.3	1.3	1.1	0.3
Age started oral contraceptive pill	0.7	0.9	2.0	0.8	0.7	0.8	0.6	0.3	-0.7	-0.9	-1.4	-1.1	1.3	0.0	-1.1	-0.4	-1.2	-1.4	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.6	-1.2	-1.2	-1.0	-0.3	-0.7	1.6	1.0	0.8	1.0	-0.8	-0.6	0.8	1.1	0.7	1.3	0.4
Ovarian Cancer	0.6	0.8	1.8	0.9	0.5	0.9	1.3	0.8	-1.1	-1.0	-1.3	-0.8	0.7	0.8	-1.1	-0.9	-1.0	-0.8	-0.1
Crohns Disease (2012)	0.6	0.9	4.0	-0.6	-0.5	-1.2	0.0	-0.7	1.0	0.7	1.1	2.0	-0.3	-0.0	1.0	0.7	1.1	1.7	1.1
Rheumatoid Arthritis	0.6	0.8	4.8	-1.0	-0.3	-0.6	-1.2	-0.3	0.4	0.7	-0.2	1.4	-0.8	-0.6	0.9	-0.3	1.0	0.7	2.2
Lung FEV1/FVC ratio	0.6	3.3	13.8	-0.4	1.5	1.0	0.1	-0.7	-1.2	-2.0	-2.8	-2.4	2.5	1.1	-1.7	-3.7	-0.9	-2.7	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.9	0.4	0.1	0.5	0.5	-1.6	-0.2	-0.9	-0.5	-1.6	0.5	0.6	-0.8	-1.7	-0.5	-1.7	-0.1
Qualifications: CSEs or equivalent	0.6	0.8	2.2	0.8	-0.1	0.5	-0.0	-1.5	-0.9	-1.1	-1.5	-1.0	1.1	0.8	-0.7	-1.2	-0.5	-1.4	0.2
Hair/balding pattern: Pattern 2	0.6	0.8	2.5	-1.3	-0.2	-1.2	-0.1	-0.4	0.8	1.1	0.8	0.9	-0.9	-0.2	0.9	1.0	1.0	1.6	0.3
Had menopause	0.6	0.7	3.8	-0.1	-0.5	-0.5	0.1	-1.9	0.1	-0.7	-0.5	-0.9	1.1	1.0	-0.1	-1.6	0.8	-0.7	-0.3
Worrier / anxious feelings	0.6	1.2	4.4	-1.4	-0.3	-1.2	-1.8	-1.7	0.9	0.6	0.1	0.5	-1.0	-0.3	0.8	-1.5	1.2	-0.1	2.1
Pulse rate	0.6	1.0	3.9	-0.3	-2.0	-0.5	-0.1	-1.3	0.4	0.9	1.4	1.1	-1.5	-0.1	0.8	1.2	0.8	1.2	-0.3
Headache pain in last month	0.6	1.0	4.0	-0.5	0.2	-1.0	-0.4	-2.0	-0.2	-0.4	-0.8	-1.2	-0.5	1.3	-0.1	-2.0	0.9	-1.1	0.9
Number of full sisters	0.6	0.8	2.2	0.6	1.4	-0.2	0.5	0.9	-1.4	-0.4	0.7	-0.2	-1.5	1.2	-0.4	-1.2	0.1	0.6	-1.3
Suffer from ‘nerves’	0.6	0.9	4.5	-1.3	-0.3	-0.9	-1.4	-1.3	1.3	0.7	0.4	-0.0	-0.5	-0.7	0.8	-0.8	1.0	-0.2	2.1
Whole body fat-free mass	0.6	3.5	11.4	-1.4	-2.2	-2.4	-3.4	-2.9	3.1	1.2	1.0	0.4	2.4	-1.3	1.4	0.6	1.3	0.3	1.9
Mood swings	0.6	1.0	7.1	-0.6	1.8	-0.0	-0.5	-0.4	0.0	-0.9	-0.9	-0.5	0.7	0.8	-0.6	-2.7	0.0	-1.5	0.6
Commuting to job workplace: Walk	0.6	0.6	3.0	-0.7	-0.4	0.3	-0.1	0.9	0.5	0.8	0.7	1.1	-1.0	-0.9	0.5	1.7	0.2	1.1	-0.1
Mineral and other dietary supplements	0.6	0.7	4.8	0.6	0.5	0.8	0.5	0.1	-2.2	-0.9	-1.4	-0.1	0.2	0.3	-0.5	-1.3	-0.3	-1.2	0.3
Breast cancer (self-reported)	0.6	0.7	2.9	1.2	-0.2	1.1	0.4	0.6	-0.1	-0.5	0.0	0.1	1.0	-0.7	-0.9	0.8	-1.6	0.0	-1.7
Whole body water mass	0.6	3.5	11.4	-1.3	-2.2	-2.3	-3.4	-2.9	3.1	1.2	1.0	0.4	2.4	-1.4	1.4	0.6	1.3	0.3	1.8
Alcohol drinker status: Never	0.6	0.7	1.7	0.8	0.1	0.2	1.0	-0.4	-1.3	-0.9	-0.7	-1.1	0.2	1.1	-0.9	-1.3	-0.7	-0.9	0.2
HDL Cholesterol	0.5	0.8	3.8	-0.8	-1.0	-0.5	-0.7	-1.1	-0.2	0.9	1.3	1.1	-1.9	-0.0	0.6	-0.1	1.0	0.9	0.8
Blood Red Count	0.5	5.1	24.0	0.9	0.8	-0.2	-0.2	-1.1	-1.5	-1.9	-4.9	-3.7	4.0	2.2	-1.2	-2.5	-0.4	-3.4	0.5
Blood White Count	0.5	3.7	8.4	-2.5	-0.0	-1.4	-2.0	-0.8	1.5	1.8	2.9	2.4	-2.9	-0.7	2.0	-0.3	2.7	2.5	2.2
Heel T-Score	0.5	3.7	7.6	2.5	1.9	2.0	1.5	2.0	-1.6	-2.1	-0.9	-1.0	2.5	1.9	-2.4	-0.4	-2.6	-1.9	-2.8
Diabetes (mother)	0.5	0.6	3.1	-0.3	-0.7	-0.1	-1.4	-0.5	0.5	0.6	-0.2	0.3	0.9	-1.8	0.6	1.4	-0.1	-0.1	0.5
Leg fat-free mass (left)	0.5	2.9	13.5	-0.7	-1.6	-1.6	-3.1	-3.1	2.4	0.2	-0.1	-0.3	3.7	-0.7	0.6	-0.7	0.8	-0.8	1.4
Taking other prescription medications	0.5	0.8	3.8	1.2	0.4	1.1	-0.0	0.7	-1.2	-1.2	-0.4	-0.2	1.2	0.7	-0.8	-1.9	-0.5	-0.4	0.4
Leg predicted mass (left)	0.5	2.8	13.4	-0.7	-1.6	-1.6	-3.1	-3.0	2.4	0.2	-0.1	-0.2	3.7	-0.7	0.6	-0.7	0.8	-0.7	1.4
Waist circumference	0.5	2.0	13.8	1.2	-0.4	1.9	-0.9	-0.2	0.8	-1.1	-0.8	-1.3	3.7	-1.1	-1.3	0.2	-1.9	-1.5	-1.0
Hearing difficulty/problems with background noise	0.5	0.7	1.8	1.0	-0.3	1.3	1.2	0.7	-0.6	-0.9	-0.7	-1.1	0.9	0.1	-1.1	0.3	-1.2	-0.7	-0.9
Qualifications: None of the above	0.5	1.1	3.2	1.4	0.4	1.8	0.5	1.1	-0.4	-1.0	1.0	-0.6	1.3	0.4	-1.2	-0.3	-1.4	-0.4	-1.8
Allergy	0.5	1.1	4.1	0.5	1.8	1.3	-0.1	1.2	-1.0	-0.9	-1.0	-1.0	2.0	-0.2	-1.1	-0.4	-1.3	-0.8	-0.2
Fluid intelligence score	0.5	1.1	4.4	-1.4	0.6	-0.7	-1.5	0.9	0.7	1.0	-0.3	1.2	-0.4	-2.1	1.0	0.4	0.6	1.1	1.7
Neuroticism score	0.5	1.1	8.5	-1.2	0.8	-0.8	-0.9	-1.2	1.0	0.0	-0.0	0.4	-0.6	0.2	0.2	-2.9	1.0	-0.9	1.1
Weight	0.5	2.6	22.9	0.8	-0.6	0.7	-2.1	-1.9	1.4	-1.0	-1.1	-1.3	4.8	-0.5	-0.9	-1.0	-0.9	-1.9	-0.2
Father’s age at death	0.5	0.6	2.6	-0.4	0.3	0.2	0.5	1.6	0.5	0.5	0.9	0.6	-0.3	-0.9	-0.1	1.6	-0.7	0.2	-1.3
Falls in the last year	0.5	0.7	2.6	0.6	1.0	1.6	0.8	0.9	-1.1	-0.6	-0.9	-0.4	0.3	-0.1	-1.0	0.6	-1.4	-0.5	-0.4
Hair/balding pattern: Pattern 3	0.5	0.8	2.1	-0.5	-1.4	-0.9	-1.3	-0.7	1.0	0.8	0.4	0.9	0.1	-1.3	1.0	0.6	0.8	0.6	1.1
Medication: Cholesterol lowering	0.5	0.7	3.9	1.0	0.9	1.1	0.8	2.0	-0.6	-0.7	0.6	-0.3	0.1	0.6	-0.9	-0.3	-0.8	-0.1	-1.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	3.0	-0.7	0.1	-1.7	-0.3	-0.4	-0.0	0.6	-0.4	-0.3	-1.6	0.5	0.7	-0.8	1.2	0.3	0.5
Glaucoma (self-reported)	0.5	0.6	2.7	0.7	1.7	0.8	0.9	1.3	-0.5	-0.9	-0.8	-0.6	0.1	0.9	-0.7	-0.4	-0.8	-0.2	0.1
Medication: Omeprazole	0.5	0.6	3.0	0.7	-0.0	0.5	-1.0	-1.0	0.5	-0.7	0.0	0.4	1.7	0.1	-0.4	-1.6	-0.2	-0.7	0.9
Arm predicted mass (right)	0.5	2.5	8.3	-1.0	-1.9	-2.0	-2.9	-2.3	2.8	1.0	0.7	0.1	2.2	-1.1	1.2	0.5	1.1	0.1	1.3
Leg fat-free mass (right)	0.5	2.9	10.6	-0.9	-1.6	-2.0	-3.1	-3.1	2.6	0.5	0.2	0.0	3.3	-0.7	0.8	-0.6	1.1	-0.4	1.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	3.0	1.0	-0.1	0.8	0.5	-0.5	-0.1	-0.9	-0.2	-1.1	1.7	-0.1	-1.0	-0.9	-1.0	-0.9	-0.3
Ever had bowel cancer screening	0.5	0.5	3.7	-0.3	-0.7	-0.8	-0.5	-1.3	-0.1	-0.0	-1.0	0.1	-0.3	0.4	0.2	-1.9	0.7	-0.2	0.7
Leg predicted mass (right)	0.5	2.8	10.7	-0.9	-1.6	-2.0	-3.0	-3.0	2.6	0.4	0.1	-0.0	3.3	-0.6	0.8	-0.7	1.0	-0.4	1.6
Miserableness	0.5	0.9	7.3	-1.2	0.8	-1.2	-0.2	-0.9	0.6	-0.2	-0.8	0.2	-0.7	0.9	0.1	-2.7	1.1	-0.5	0.4
Medication: Paracetamol	0.5	0.7	2.3	0.4	-0.5	0.4	0.8	-0.9	-0.5	-1.0	-0.6	-1.5	0.3	0.9	-1.0	-1.0	-0.8	-1.4	-0.7
Basal metabolic rate	0.5	2.7	9.7	-0.8	-1.9	-1.6	-3.1	-2.8	2.7	0.6	0.5	0.0	3.1	-1.1	0.9	0.2	0.8	-0.3	1.3
Arm fat-free mass (left)	0.5	2.3	8.1	-0.6	-2.2	-1.7	-2.6	-2.8	2.4	0.6	0.7	-0.1	2.5	-0.8	0.9	0.2	0.9	-0.1	1.1
Risk taking	0.5	0.7	2.6	-0.7	0.3	0.1	0.2	0.2	-0.6	0.9	-0.3	1.0	-1.6	-1.1	0.7	1.6	0.1	1.4	0.7
Fractured/broken bones in last 5 years	0.5	0.6	4.7	-0.3	-2.2	-0.6	-1.0	-1.6	-0.0	0.4	0.8	-0.2	-0.4	-0.0	0.5	0.5	0.7	0.6	0.3
Worry (Nagel 2018)	0.4	0.7	3.5	-1.0	0.1	-0.7	-0.8	-1.1	1.1	0.4	0.5	0.1	-1.1	0.3	0.3	-1.9	0.8	-0.5	1.4
Verbal and Numeric Reasoning (VNR)	0.4	1.0	3.9	-1.2	0.5	-1.1	-0.9	1.3	0.5	1.1	0.0	0.9	-0.9	-2.0	1.0	0.8	0.6	1.6	0.9
Triglycerides	0.4	0.6	4.1	0.5	2.0	-0.3	0.6	1.4	-0.3	-0.4	-0.7	-1.1	0.6	0.1	-0.2	0.5	-0.5	-0.4	0.3
Allergy or Eczema	0.4	1.0	8.7	-0.5	-1.1	-1.0	0.8	-0.5	-0.1	0.9	0.7	1.1	-2.9	0.3	0.8	0.4	1.1	1.1	-0.1
Hypothyroidism (self reported)	0.4	1.0	3.7	0.5	-0.3	0.5	-0.8	-1.2	0.1	-1.0	-1.4	-1.0	1.8	1.0	-0.6	-1.9	-0.1	-1.1	0.9
Lung FVC	0.4	1.9	8.2	0.2	0.2	-0.1	-0.2	-2.2	-1.2	-1.3	-1.4	-1.1	1.6	2.1	-0.4	-2.9	1.1	-1.7	1.2
Neuroticism	0.4	1.0	7.1	-1.5	1.1	-0.5	-0.8	-0.7	1.3	0.2	-0.0	0.4	-0.6	-0.0	0.1	-2.7	0.8	-0.9	0.7
Frequency of depressed mood in last 2 weeks	0.4	0.5	2.2	0.1	0.2	0.3	0.9	-1.0	-0.3	-0.6	0.1	-1.3	-0.7	0.8	-0.6	-1.5	-0.1	-1.2	0.1
Relative age of first facial hair	0.4	0.8	5.4	-1.0	-0.4	0.4	-0.2	0.4	-0.3	0.9	0.7	0.5	-2.3	-1.1	0.6	1.3	0.1	1.1	0.2
Medication: Co-codamol	0.4	0.5	2.2	0.7	-0.0	0.3	0.1	0.2	-1.4	-0.8	0.3	-0.3	0.7	1.2	-0.3	-1.5	0.3	-0.6	0.1
Had other major operations	0.4	0.5	3.5	-0.0	1.3	0.6	0.3	0.5	-0.4	-0.6	-1.9	0.5	0.3	0.5	-0.6	-0.6	-0.5	0.1	-0.3
Tense / ‘highly strung’	0.4	0.7	3.6	0.4	1.4	0.2	1.2	0.1	-0.3	-0.5	-0.6	-1.0	-0.5	1.0	-0.6	-1.9	-0.0	-1.1	0.2
Medication: Amlodipine	0.4	0.6	1.7	0.9	1.0	0.9	0.4	1.3	-0.9	-0.8	-0.1	-1.0	0.9	0.3	-0.8	0.0	-1.1	-0.9	-0.2
Arm fat-free mass (right)	0.4	2.1	7.5	-0.6	-1.7	-1.5	-2.7	-2.3	2.5	0.6	0.5	-0.3	2.7	-0.9	0.7	0.3	0.6	-0.3	1.1
Number of children fathered	0.4	0.5	1.5	-0.8	-0.5	-1.1	-1.2	-0.9	0.3	0.5	-0.1	0.5	-0.4	-0.6	0.7	-0.4	0.8	0.3	1.0
Pulse wave peak to peak time	0.4	0.5	1.8	-0.8	0.5	-0.1	-0.4	0.6	1.0	0.4	0.3	1.1	0.4	-1.0	0.3	1.3	-0.2	0.5	0.7
Pulse rate, automated reading	0.4	1.4	8.4	-0.6	-0.2	0.8	0.5	1.3	-0.2	1.1	1.4	1.2	-2.9	-0.9	0.4	1.8	-0.3	1.7	-0.3
Leg pain on walking	0.4	0.5	3.2	0.8	-0.7	0.6	0.1	-1.8	-0.1	-0.6	-0.2	0.4	1.0	0.6	-0.7	-0.7	-0.4	-0.7	-1.0
Eye problems/disorders: Cataract	0.4	0.4	1.9	0.2	-0.1	-0.9	0.5	-1.4	0.8	0.3	1.4	-0.1	-0.2	0.4	0.6	-0.5	1.0	-0.3	0.1
Financial situation satisfaction	0.4	0.5	1.9	1.1	-0.5	0.5	1.0	-0.6	-1.1	-0.9	0.1	-1.0	0.1	1.4	-0.7	-0.3	-0.3	-0.6	-0.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.7	-1.2	-0.4	-0.2	-0.5	-0.1	0.5	0.8	0.4	-0.0	-1.6	-1.2	0.5	0.4	0.3	0.5	0.1
Depression (Nagel 2018)	0.3	0.5	1.4	0.3	0.6	0.7	1.1	-0.0	-0.4	-0.5	0.0	-1.1	-0.8	0.7	-0.8	-0.9	-0.6	-1.2	-0.9
Neuroticism (Nagel 2018)	0.3	0.6	5.1	-0.7	0.9	-0.2	-0.2	-0.5	1.0	-0.3	-0.2	-0.2	-0.3	0.2	-0.2	-2.3	0.4	-1.4	0.6
Crohns Disease (2017)	0.3	0.6	3.5	0.1	0.2	-0.5	-0.3	0.2	1.0	0.3	1.0	1.9	0.8	-0.4	0.5	0.7	0.4	1.2	0.3
Impedance of leg (right)	0.3	1.4	11.6	-0.3	0.2	1.2	0.5	1.4	-1.5	0.7	0.6	1.0	-3.4	-0.6	0.7	1.0	0.5	1.0	0.4
Fed-up feelings	0.3	0.6	2.7	-1.2	0.4	-0.3	-0.8	-0.5	0.9	0.2	0.6	0.5	-0.9	-0.3	0.3	-1.7	0.7	-0.1	1.3
Medication: Atenolol	0.3	0.3	1.1	1.0	0.3	0.5	0.5	0.7	-0.9	-0.7	-1.1	-0.3	0.2	0.2	-0.5	-0.8	-0.6	-0.2	-0.1
Impedance of leg (left)	0.3	1.7	14.7	-0.3	0.6	1.1	0.8	1.6	-1.6	0.8	0.8	1.3	-3.8	-0.6	0.8	0.9	0.6	1.3	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.2	-0.8	-0.5	-0.2	-0.7	-1.3	0.3	0.3	0.1	-0.1	-0.9	-0.2	0.5	-0.9	0.7	-0.7	1.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.9	-0.3	-0.7	-0.5	0.1	0.0	0.8	0.8	0.4	0.7	-1.4	-0.2	0.6	0.6	0.5	0.5	0.8
Mouth/teeth dental problems: Dentures	0.3	0.5	2.4	-0.5	0.5	-0.4	-0.2	1.6	1.0	0.2	-0.1	0.6	0.7	-1.2	0.0	0.8	-0.3	0.4	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.2	0.1	0.4	-0.3	0.6	-0.8	0.1	-0.3	-0.3	-1.0	-0.5	1.1	-0.3	-1.0	0.4	0.1	-0.6
Pulse wave Arterial Stiffness index	0.3	0.3	1.4	0.5	-0.5	-0.2	-0.0	-0.7	-0.8	-0.2	-0.2	-1.0	-0.5	0.8	-0.0	-1.2	0.4	-0.2	-0.3
Impedance of arm (left)	0.3	1.3	6.6	-1.4	0.3	0.3	-0.7	0.5	-0.8	1.1	0.0	1.9	-2.6	-0.9	1.1	0.2	1.1	1.3	1.6
Exposure to tobacco smoke at home	0.3	0.3	1.5	0.3	-0.3	0.8	0.3	-0.1	-0.4	-0.5	0.2	-0.6	1.2	-0.4	-0.4	-0.4	-0.5	-1.1	-0.2
Medication: Paracetamol	0.3	0.4	1.4	-0.1	-0.2	-0.0	0.4	-0.8	-0.7	-0.7	0.0	-1.2	-0.4	1.0	-0.6	-1.1	-0.3	-1.0	-0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.1	0.6	-0.1	0.6	-0.3	-0.7	-0.1	-0.9	-1.5	-0.4	1.4	0.3	-0.6	-1.0	-0.5	-1.0	0.3
Neck or shoulder pain in last month	0.3	0.5	2.7	0.1	0.7	0.8	0.4	-0.4	-0.4	-0.7	-1.3	-0.6	0.3	0.5	-0.5	-1.6	0.1	-0.8	0.5
Had major operations	0.3	0.4	1.2	-0.3	-0.4	-0.0	1.0	0.8	0.2	0.5	1.0	0.4	-0.9	-0.4	0.4	1.1	0.0	1.0	0.5
Medication: Aspirin	0.3	0.4	1.4	0.6	-0.6	0.7	0.7	0.3	-0.5	-0.5	-0.0	-0.6	0.1	0.3	-0.9	0.6	-1.2	-0.4	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	2.2	0.1	0.1	-0.1	-0.5	-1.1	0.1	-0.5	-0.6	-0.8	0.8	1.1	-0.2	-1.5	0.5	-0.5	0.1
Medication: Gliclazide	0.3	0.3	0.8	0.6	-0.5	0.9	0.6	0.2	-0.1	-0.1	-0.8	-0.3	0.7	0.1	-0.6	0.5	-0.8	-0.3	-0.9
Pain type(s) experienced in last month: Hip pain	0.3	0.4	2.7	-0.3	0.7	-0.3	-0.4	-0.3	-0.6	-0.5	-0.7	0.3	0.7	0.5	-0.0	-1.6	0.6	-0.4	0.8
Irritability	0.3	0.4	1.8	-0.0	1.0	0.8	0.2	0.6	0.0	-0.6	-1.0	0.1	0.5	-0.2	-0.5	-1.4	-0.5	-1.2	-0.1
Myopia	0.3	0.4	2.8	0.1	-1.0	-0.1	-0.6	-1.7	0.3	0.2	1.3	0.1	-0.5	-0.3	0.2	0.1	0.1	0.9	0.3
Arm predicted mass (left)	0.3	1.7	9.6	-0.1	-1.6	-1.1	-2.2	-2.3	1.9	0.0	0.1	-0.7	3.1	-0.5	0.2	-0.0	0.2	-0.7	0.7
Depressed Affect (Nagel 2018)	0.2	0.4	3.4	-0.5	1.2	0.1	0.4	0.4	0.4	-0.4	0.2	0.1	-0.8	0.3	-0.3	-1.8	0.1	-0.7	0.1
Alzheimer’s Disease (in father)	0.2	0.2	0.8	0.2	0.4	0.9	0.1	0.1	-0.1	-0.3	-0.1	0.1	-0.6	0.8	-0.3	-0.0	-0.4	0.4	0.7
Ulcerative Colitis (UC)	0.2	0.5	2.2	0.5	1.5	0.3	0.8	0.8	-0.5	-0.7	-1.1	0.1	0.6	0.2	-0.7	-0.5	-0.6	-0.0	-0.8
Major Depression (MDD)	0.2	0.3	1.4	-0.4	0.6	0.0	-0.6	0.9	0.5	0.6	-0.1	0.2	-0.2	-0.3	0.4	1.2	0.1	0.6	0.3
Breast Cancer	0.2	0.6	1.5	0.6	-0.0	1.2	0.6	-0.5	-0.6	-1.0	-0.2	-0.9	0.2	1.2	-1.0	-0.4	-0.8	-0.7	-1.1
LDL Cholesterol	0.2	0.3	1.0	-0.3	0.9	-0.3	-0.1	0.8	0.6	0.2	0.7	-0.1	-0.5	-0.2	0.5	0.1	0.7	1.0	0.2
Neuroticism (2016)	0.2	0.2	1.6	0.4	0.3	0.5	0.5	-0.7	-0.4	-0.4	-0.4	-0.4	-0.4	0.5	-0.4	-1.3	-0.1	-0.1	-0.1
Ulcerative Colitis	0.2	0.3	1.4	-0.1	1.2	-0.3	1.0	1.1	-0.1	-0.4	-0.8	0.1	0.3	0.2	-0.4	-0.4	-0.2	0.1	-0.4
Blood Eosinophil Count	0.2	1.5	10.0	-0.3	0.8	-1.1	-0.2	0.1	-1.3	-0.4	1.1	0.4	-1.2	1.8	0.2	-3.2	1.5	0.6	1.7
Respiratory disease	0.2	0.3	1.4	0.7	-0.8	0.1	1.2	0.3	1.1	-0.1	0.2	-0.2	0.0	0.5	-0.3	0.4	-0.4	-0.0	-1.1
Hearing difficulty/problems: Yes	0.2	0.3	0.9	0.1	-0.9	0.2	-0.4	0.4	0.3	0.1	0.6	-0.4	0.8	-0.8	-0.0	0.8	-0.4	-0.1	-0.6
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.3	-0.1	-0.3	0.9	-0.1	1.0	1.1	-0.1	-0.1	0.3	0.8	-0.4	-0.4	0.7	-0.8	-0.1	-0.3
Medication for hormone replacement therapy	0.2	0.3	1.1	0.3	0.3	0.2	0.1	-0.2	-0.5	-0.6	-0.6	-0.4	0.9	1.0	-0.4	-1.1	0.1	-0.6	-0.0
Average weekly fortified wine intake	0.2	0.2	0.8	0.1	0.1	0.2	-0.1	0.9	0.8	0.2	0.8	-0.1	0.2	-0.6	0.1	0.8	-0.2	0.3	0.7
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	0.7	0.2	0.9	0.0	-0.5	-0.2	-0.5	-0.4	-0.7	0.8	0.3	-0.5	0.2	-0.6	-0.3	0.1
Medication: Levothyroxine sodium	0.2	0.4	2.1	0.7	0.2	0.8	-0.2	-0.5	-0.3	-0.8	-1.0	-0.5	1.4	0.2	-0.4	-0.4	-0.5	-0.6	0.5
Number of incorrect matches in round	0.2	0.3	1.6	-0.3	-0.1	-0.5	0.0	-0.5	0.2	0.6	0.0	0.8	-1.3	-0.0	0.7	0.2	0.8	0.5	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.6	0.7	0.9	1.1	0.5	1.3	-0.4	-0.5	0.2	-0.2	0.6	0.6	-0.7	0.4	-0.8	-0.9	-1.0
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.7	0.7	0.8	0.3	0.7	0.8	0.9	-0.5	-0.2	0.1	0.8	0.3	-0.4	-0.2	-0.4	-0.1	0.3
Heart attack	0.2	0.3	2.1	1.1	-0.1	0.5	0.3	0.2	0.1	-0.6	-0.2	-0.1	1.5	0.1	-0.6	-0.1	-0.7	-0.3	-0.2
Medication: Simvastatin	0.2	0.2	0.9	0.8	-0.3	0.3	-0.3	0.4	0.8	-0.4	0.5	-0.3	0.9	0.1	-0.5	-0.2	-0.5	0.2	-0.7
Impedance of arm (right)	0.2	1.1	5.2	-1.3	-0.1	0.3	-0.8	0.0	-0.7	0.9	0.2	1.5	-2.3	-0.7	1.1	0.1	1.2	1.2	1.6
Alcohol intake versus 10 years previously	0.2	0.3	0.8	0.9	-0.8	-0.4	-0.5	-0.9	-0.4	-0.3	-0.7	0.4	0.5	0.6	0.1	-0.8	0.3	0.5	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.4	-0.0	0.0	-0.0	-0.8	-0.7	-0.1	-0.4	-0.4	-0.2	0.6	0.4	0.0	-1.2	0.4	-0.8	1.1
Number of live births	0.2	0.3	0.9	0.6	-0.2	0.9	0.4	-0.1	0.3	-0.3	0.1	-0.4	0.5	-0.3	-0.6	0.6	-1.0	-0.6	-0.9
Happiness	0.2	0.3	1.2	0.0	0.5	-0.1	-0.1	-0.6	-0.1	-0.4	-0.8	-0.8	0.5	0.2	-0.2	-0.8	-0.1	-1.1	0.7
Medication: Lansoprazole	0.2	0.3	1.8	0.5	-0.4	0.3	-0.5	-0.1	0.3	-0.5	-0.5	-0.8	1.3	-0.1	-0.3	-0.5	-0.2	-0.7	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	2.0	-0.5	1.0	-0.2	-0.0	0.5	1.4	0.0	-0.2	0.3	0.6	-0.3	0.0	-0.4	0.3	-0.6	-0.4
Medication: Ventolin 100micrograms inhaler	0.2	0.2	1.1	0.9	-0.8	1.0	0.2	0.1	-0.1	-0.6	0.1	-0.3	0.4	0.5	-0.5	-0.2	-0.5	-0.5	-0.1
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.9	0.3	-0.7	-0.3	0.1	-0.7	0.5	0.3	0.6	-0.2	0.1	-0.3	0.1	0.8	-0.1	0.6	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.9	-0.0	0.0	-0.2	-0.4	0.4	1.3	0.2	1.4	0.5	0.6	-0.8	0.3	0.3	0.1	0.2	0.3
Medication for pain relief, constipation, heartburn	0.2	0.3	1.5	-0.2	1.0	0.3	0.1	1.2	-0.1	0.4	-0.4	0.8	0.1	-1.0	0.3	1.1	-0.2	0.3	0.3
Angina (self-reported)	0.2	0.2	1.3	0.5	0.1	0.2	0.1	1.1	-0.4	-0.2	-0.0	0.2	0.4	-0.7	-0.1	0.9	-0.6	0.1	-0.1
Medication: Ibuprofen	0.2	0.2	0.8	0.1	-0.1	-0.3	0.4	-0.9	0.4	-0.2	-0.2	-0.9	-0.4	0.7	-0.2	-0.4	0.2	0.2	-0.9
Knee pain experienced in last month	0.2	0.3	1.1	0.9	0.1	0.6	0.3	0.1	-0.2	-0.7	-0.2	-0.7	1.1	0.5	-0.7	-0.7	-0.6	-0.7	-0.6
Osteoporosis (self-reported)	0.2	0.3	1.4	0.2	-0.1	0.4	0.5	0.7	-0.7	-0.2	0.2	0.6	-0.1	-0.5	-0.4	0.9	-0.7	0.1	-1.2
Smoking status: Current	0.2	0.3	1.0	0.0	0.2	0.5	0.7	0.3	-1.0	0.1	-0.2	-0.4	-1.0	-0.3	-0.3	0.7	-0.6	0.3	-0.8
Hearing aid user	0.2	0.2	0.9	-0.4	-0.5	0.1	-0.6	-0.1	0.5	0.0	0.9	-0.5	-0.1	-0.9	0.0	-0.1	-0.3	-0.4	0.4
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.7	0.2	0.3	-0.3	-0.0	-0.1	1.3	0.2	0.0	-0.9	0.5	0.1	-0.1	0.7	-0.2	0.3	-1.1
Number of operations (self-reported)	0.2	0.2	1.0	-0.6	0.4	0.8	0.0	0.9	0.8	0.2	-0.1	1.0	-0.0	-0.5	0.0	0.3	-0.1	0.5	-0.3
Ever depressed for a whole week	0.2	0.2	1.0	0.4	0.3	0.1	0.2	0.1	1.0	-0.1	-0.1	0.2	0.6	-0.4	-0.2	0.3	-0.7	-0.2	0.9
Pain experienced in last month	0.2	0.3	1.4	0.5	0.9	0.0	0.7	1.2	-0.3	-0.0	-0.0	-0.1	0.1	-0.3	-0.3	0.4	-0.8	0.0	-0.5
Impedance of whole body	0.2	1.2	10.9	-0.6	0.4	0.8	0.4	1.0	-1.6	0.7	-0.0	1.3	-3.3	-0.4	0.8	0.2	0.8	1.0	0.8
Irritable Bowel Disease (IBD)	0.1	0.3	1.6	0.4	1.3	-0.0	0.6	0.6	0.2	-0.4	-0.3	1.1	1.0	-0.0	-0.3	-0.1	-0.2	0.5	-0.2
Primary Biliary Cirrhosis	0.1	0.2	0.7	-0.1	-0.1	-0.8	0.5	0.1	0.2	0.2	0.4	0.8	-0.3	-0.8	-0.0	-0.2	-0.2	0.3	-0.7
Tanning	0.1	1.0	3.9	0.9	1.9	0.6	0.3	2.0	-0.4	-0.8	0.6	-0.2	1.6	0.0	-0.7	-0.9	-0.7	-0.7	-1.2
Angina	0.1	0.2	1.0	0.4	0.1	0.2	-0.0	1.0	-0.3	-0.2	-0.0	0.2	0.4	-0.8	-0.1	0.9	-0.5	0.0	-0.1
Diabetes (father)	0.1	0.2	0.9	0.4	0.3	-0.0	0.0	-0.7	-0.0	-0.3	-0.6	-0.9	0.4	-0.2	-0.1	-0.2	-0.3	-0.6	0.0
Severe depression (siblings)	0.1	0.1	0.5	0.7	0.1	-0.1	0.2	0.4	-0.4	-0.4	0.3	0.2	0.4	0.2	0.1	-0.1	0.3	0.3	-0.4
Townsend deprivation index at recruitment	0.1	0.2	0.7	-0.8	-0.2	-0.5	-0.6	-0.1	-0.5	0.1	0.7	-0.4	-0.4	-0.1	-0.0	-0.5	0.1	-0.0	0.2
Current tobacco smoking	0.1	0.2	0.8	-0.1	0.4	0.5	0.4	0.6	-0.6	0.2	-0.4	-0.4	-0.7	-0.6	-0.2	0.9	-0.7	0.3	-0.7
Age when periods started (menarche)	0.1	0.3	1.5	-0.0	-0.1	0.4	1.2	0.4	-0.6	-0.1	0.0	-0.0	-1.2	0.8	-0.4	0.6	-0.6	0.2	-0.3
Financial difficulties in last 2 years	0.1	0.2	0.8	0.4	-0.6	0.6	0.9	-0.1	-0.7	-0.1	0.5	-0.0	-0.8	-0.2	-0.1	0.3	-0.2	-0.1	-0.1
Mouth/teeth dental problems	0.1	0.2	0.9	0.4	-0.0	0.9	0.7	-0.1	-0.9	-0.1	0.5	0.1	-0.5	0.5	-0.3	0.2	-0.5	0.1	0.2
Asthma	0.1	0.3	1.3	0.7	-0.4	0.2	1.0	0.6	0.4	-0.3	0.3	-0.5	-0.3	0.6	-0.4	0.1	-0.5	-0.3	-1.1
Loneliness, isolation	0.1	0.2	0.8	-0.6	-0.2	-0.4	-0.2	-0.5	-0.0	0.2	0.4	0.3	-0.4	-0.7	0.3	-0.9	0.6	0.1	0.4
Friendships satisfaction	0.1	0.1	0.4	0.1	0.3	-0.6	0.2	-0.2	-0.3	0.2	-0.1	-0.3	-0.6	0.4	0.3	0.1	0.4	-0.1	0.1
Qualifications: nursing, teaching	0.1	0.1	0.9	-0.4	0.0	-0.4	0.2	-0.1	0.9	0.3	-0.3	0.4	-0.0	-0.4	0.0	0.5	-0.1	-0.2	-0.4
Asthma (self-reported)	0.1	0.2	0.8	0.4	-0.3	-0.0	0.7	0.7	0.6	-0.0	0.4	-0.3	-0.5	0.3	-0.2	0.2	-0.4	-0.3	-0.9
Heart attack/myocardial infarction (self-reported)	0.1	0.1	1.2	0.8	-0.4	0.0	0.0	0.1	0.4	-0.3	0.3	0.2	1.1	-0.1	-0.2	-0.0	-0.3	0.1	0.1
Hair Pigment	0.0	1.4	4.3	-1.3	-2.1	-0.7	-1.6	-1.9	1.7	1.1	0.9	0.3	0.4	-1.6	1.1	0.1	1.0	-0.9	0.7

Hub : Genes

MAP6D1

Models

Trait associations