TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
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chr5:152,677,967-154,117,397
Best TWAS P=1.82e-08 · Best GWAS P=7.32e-11 conditioned to 3.23e-07
152.6M
152.8M
153M
153.2M
153.4M
153.6M
153.8M
154M
154.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
ROSMAP
Brain Pre-frontal Cortex
FAM114A2
0.05
0.06
lasso
6
0.05
6.3e-07
-5.6
5.6
1.8e-08
0.29
0.75
0.24
TRUE
1
CommonMind
Brain Pre-frontal Cortex
FAM114A2
0.28
0.39
lasso
9
0.41
1.8e-53
-5.0
5.3
9.0e-08
0.22
0.97
0.03
FALSE
4
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
FAM114A2
0.07
0.06
blup
56
0.06
1.5e-03
-5.0
-5.3
1.5e-07
-0.15
0.03
0.57
FALSE
2
NTR
Blood
FAM114A2
0.04
0.03
lasso
10
0.02
8.9e-08
-5.0
5.2
1.8e-07
0.18
0.97
0.03
FALSE