Best TWAS P=1.08e-09 · Best GWAS P=9.2e-13 conditioned to 4.75e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pituitary | ZMYND12 | 0.18 | 0.01 | enet | 22 | 0.04 | 3.9e-02 | -4.6 | -5.1 | 2.7e-07 | -0.31 | 0.07 | 0.14 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RIMKLA | 0.06 | 0.06 | bslmm | 341 | 0.05 | 1.3e-07 | -3.9 | 6.1 | 1.1e-09 | 0.16 | 0.98 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | RIMKLA | 0.03 | 0.02 | blup | 53 | 0.01 | 2.8e-02 | 4.7 | 5.4 | 5.8e-08 | 0.23 | 0.00 | 0.75 | FALSE |