[Hub]/) : Traits : Whole body fat-free mass : ← →

chr6:80,120,201-81,872,212

Best TWAS P=6.63e-22 · Best GWAS P=6.99e-18 conditioned to 0.0537

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Heart Atrial Appendage	RP11-250B2.6	0.20	0.00	enet	17	0.03	2.6e-02	-4.4	-9.6	6.6e-22	-0.41	0.05	0.50	TRUE
8	GTEx	Colon Transverse	RP11-250B2.5	0.13	0.02	enet	3	0.01	6.3e-02	-2.9	-5.5	3.2e-08	-0.61	0.06	0.48	TRUE
6	GTEx	Cells Transformed fibroblasts	BCKDHB	0.16	0.02	enet	42	0.04	3.7e-04	5.1	8.7	4.9e-18	0.49	0.25	0.64	FALSE
15	GTEx	Muscle Skeletal	RP11-250B2.6	0.07	0.04	lasso	5	0.04	4.2e-05	8.4	-8.6	1.3e-17	-0.94	0.02	0.98	FALSE
4	GTEx	Brain Cerebellum	RP11-250B2.5	0.43	0.11	lasso	5	0.14	4.7e-05	-7.8	-7.7	1.9e-14	-0.76	0.08	0.82	FALSE
9	GTEx	Esophagus Mucosa	RP11-250B2.6	0.20	0.16	lasso	7	0.23	3.3e-15	-7.6	-7.6	3.6e-14	-0.65	0.90	0.10	FALSE
1	GTEx	Adipose Visceral Omentum	RP11-250B2.6	0.16	0.05	lasso	6	0.06	7.8e-04	6.8	-7.5	4.8e-14	-0.57	0.20	0.48	FALSE
17	GTEx	Testis	RP11-250B2.5	0.13	0.17	lasso	3	0.14	7.0e-07	-7.7	-7.5	7.8e-14	-0.88	0.04	0.95	FALSE
14	GTEx	Lung	RP11-250B2.6	0.09	0.05	enet	16	0.07	5.3e-06	5.2	-7.3	2.9e-13	-0.36	0.83	0.02	FALSE
12	GTEx	Heart Left Ventricle	RP11-250B2.6	0.09	0.00	enet	6	0.02	2.0e-02	7.6	-7.3	3.9e-13	-0.82	0.05	0.73	FALSE
18	GTEx	Thyroid	BCKDHB	0.17	0.06	lasso	8	0.10	3.4e-08	5.2	7.0	3.6e-12	0.46	0.98	0.02	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	RP11-250B2.6	0.21	0.03	enet	37	0.13	4.7e-05	5.6	-6.6	3.2e-11	-0.23	0.14	0.08	FALSE
19	METSIM	Adipose	RP11-250B2.6	0.04	0.04	lasso	12	0.02	1.7e-04	7.3	-6.5	7.7e-11	-0.60	0.68	0.10	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BCKDHB	0.12	0.06	lasso	4	0.06	4.2e-07	6.5	-6.0	1.5e-09	-0.75	0.51	0.48	FALSE
16	GTEx	Nerve Tibial	BCKDHB	0.18	0.11	lasso	9	0.10	2.4e-07	5.6	5.7	1.5e-08	0.15	1.00	0.00	FALSE
7	GTEx	Cells Transformed fibroblasts	RP11-250B2.6	0.11	0.01	lasso	7	0.00	1.4e-01	-7.6	-5.6	1.7e-08	-0.51	0.34	0.12	FALSE
13	GTEx	Lung	BCKDHB	0.09	0.06	enet	10	0.05	1.8e-04	5.6	5.6	2.6e-08	0.15	0.89	0.02	FALSE
2	GTEx	Artery Aorta	BCKDHB	0.14	0.14	lasso	1	0.13	9.8e-08	5.5	5.5	3.9e-08	0.15	1.00	0.00	FALSE
10	GTEx	Esophagus Muscularis	BCKDHB	0.18	0.07	enet	25	0.06	2.4e-04	5.6	5.4	5.5e-08	0.15	0.94	0.01	FALSE
3	GTEx	Artery Tibial	BCKDHB	0.16	0.16	lasso	11	0.15	4.9e-12	5.6	5.3	9.2e-08	0.15	1.00	0.00	FALSE