[Hub]/) : Traits : Whole body fat-free mass :

chr6:80,120,201-81,872,212

Best TWAS P=6.63e-22 · Best GWAS P=6.99e-18 conditioned to 0.0537

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-250B2.6 0.16 0.05 lasso 6 0.06 7.8e-04 6.8 -7.5 4.8e-14 -0.57 0.20 0.48 FALSE
2 GTEx Artery Aorta BCKDHB 0.14 0.14 lasso 1 0.13 9.8e-08 5.5 5.5 3.9e-08 0.15 1.00 0.00 FALSE
3 GTEx Artery Tibial BCKDHB 0.16 0.16 lasso 11 0.15 4.9e-12 5.6 5.3 9.2e-08 0.15 1.00 0.00 FALSE
4 GTEx Brain Cerebellum RP11-250B2.5 0.43 0.11 lasso 5 0.14 4.7e-05 -7.8 -7.7 1.9e-14 -0.76 0.08 0.82 FALSE
5 GTEx Cells EBV-transformed lymphocytes RP11-250B2.6 0.21 0.03 enet 37 0.13 4.7e-05 5.6 -6.6 3.2e-11 -0.23 0.14 0.08 FALSE
6 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 5.1 8.7 4.9e-18 0.49 0.25 0.64 FALSE
7 GTEx Cells Transformed fibroblasts RP11-250B2.6 0.11 0.01 lasso 7 0.00 1.4e-01 -7.6 -5.6 1.7e-08 -0.51 0.34 0.12 FALSE
8 GTEx Colon Transverse RP11-250B2.5 0.13 0.02 enet 3 0.01 6.3e-02 -2.9 -5.5 3.2e-08 -0.61 0.06 0.48 TRUE
9 GTEx Esophagus Mucosa RP11-250B2.6 0.20 0.16 lasso 7 0.23 3.3e-15 -7.6 -7.6 3.6e-14 -0.65 0.90 0.10 FALSE
10 GTEx Esophagus Muscularis BCKDHB 0.18 0.07 enet 25 0.06 2.4e-04 5.6 5.4 5.5e-08 0.15 0.94 0.01 FALSE
11 GTEx Heart Atrial Appendage RP11-250B2.6 0.20 0.00 enet 17 0.03 2.6e-02 -4.4 -9.6 6.6e-22 -0.41 0.05 0.50 TRUE
12 GTEx Heart Left Ventricle RP11-250B2.6 0.09 0.00 enet 6 0.02 2.0e-02 7.6 -7.3 3.9e-13 -0.82 0.05 0.73 FALSE
13 GTEx Lung BCKDHB 0.09 0.06 enet 10 0.05 1.8e-04 5.6 5.6 2.6e-08 0.15 0.89 0.02 FALSE
14 GTEx Lung RP11-250B2.6 0.09 0.05 enet 16 0.07 5.3e-06 5.2 -7.3 2.9e-13 -0.36 0.83 0.02 FALSE
15 GTEx Muscle Skeletal RP11-250B2.6 0.07 0.04 lasso 5 0.04 4.2e-05 8.4 -8.6 1.3e-17 -0.94 0.02 0.98 FALSE
16 GTEx Nerve Tibial BCKDHB 0.18 0.11 lasso 9 0.10 2.4e-07 5.6 5.7 1.5e-08 0.15 1.00 0.00 FALSE
17 GTEx Testis RP11-250B2.5 0.13 0.17 lasso 3 0.14 7.0e-07 -7.7 -7.5 7.8e-14 -0.88 0.04 0.95 FALSE
18 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 5.2 7.0 3.6e-12 0.46 0.98 0.02 FALSE
19 METSIM Adipose RP11-250B2.6 0.04 0.04 lasso 12 0.02 1.7e-04 7.3 -6.5 7.7e-11 -0.60 0.68 0.10 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BCKDHB 0.12 0.06 lasso 4 0.06 4.2e-07 6.5 -6.0 1.5e-09 -0.75 0.51 0.48 FALSE