TWAS hub - BCKDHB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1140	0.0280	1.4e-09	0.094	0.083	0.077	0.086	0.084	1.8e-11	2.4e-10	1.3e-09	1.1e-10	2.1e-10
2	GTEx	Artery Aorta	0.1400	0.0480	4.4e-04	0.145	NA	0.109	NA	0.132	2.2e-08	NA	1.4e-06	NA	9.8e-08
3	GTEx	Artery Coronary	0.2920	0.0910	6.1e-04	0.051	NA	0.003	NA	0.108	8.4e-03	NA	2.4e-01	NA	1.7e-04
4	GTEx	Artery Tibial	0.1556	0.0380	7.1e-08	0.163	NA	0.140	NA	0.153	8.2e-13	NA	4.7e-11	NA	4.9e-12
5	GTEx	Brain Caudate basal ganglia	0.2140	0.0890	5.0e-03	-0.010	NA	-0.004	NA	-0.010	9.2e-01	NA	4.5e-01	NA	9.8e-01
6	GTEx	Cells EBV-transformed lymphocytes	0.1530	0.0600	4.6e-03	0.109	NA	0.068	NA	0.066	2.1e-04	NA	3.1e-03	NA	3.6e-03
7	GTEx	Cells Transformed fibroblasts	0.1640	0.0470	4.4e-06	0.021	NA	0.043	NA	0.035	9.7e-03	NA	3.7e-04	NA	1.2e-03
8	GTEx	Esophagus Mucosa	0.1740	0.0460	1.8e-06	0.161	NA	0.126	NA	0.148	6.1e-11	NA	8.8e-09	NA	3.9e-10
9	GTEx	Esophagus Muscularis	0.1780	0.0580	9.6e-05	0.071	NA	0.057	NA	0.049	4.1e-05	NA	2.4e-04	NA	6.4e-04
10	GTEx	Lung	0.0920	0.0339	8.2e-04	0.056	NA	0.046	NA	0.045	3.8e-05	NA	1.8e-04	NA	2.1e-04
11	GTEx	Nerve Tibial	0.1768	0.0510	7.4e-06	0.109	NA	0.034	NA	0.097	4.2e-08	NA	1.8e-03	NA	2.4e-07
12	GTEx	Pancreas	0.1440	0.0630	8.5e-03	0.085	NA	0.049	NA	0.047	2.0e-04	NA	3.8e-03	NA	4.6e-03
13	GTEx	Skin Sun Exposed Lower leg	0.0840	0.0300	3.8e-04	0.050	NA	0.047	NA	0.039	5.4e-05	NA	8.8e-05	NA	3.6e-04
14	GTEx	Thyroid	0.1690	0.0470	2.0e-07	0.065	NA	0.074	NA	0.102	1.1e-05	NA	2.7e-06	NA	3.4e-08
15	METSIM	Adipose	0.0489	0.0148	6.8e-07	0.034	0.047	0.043	0.046	0.046	7.4e-06	1.1e-07	4.1e-07	1.5e-07	1.9e-07
16	ROSMAP	Brain Pre-frontal Cortex	0.1826	0.0398	1.3e-14	0.133	0.129	0.115	0.129	0.137	1.1e-16	3.2e-16	1.3e-14	2.7e-16	2.9e-17
17	YFS	Blood	0.0135	0.0064	5.8e-03	0.010	0.004	0.003	0.004	0.003	2.1e-04	1.3e-02	3.7e-02	1.3e-02	3.8e-02
18	TCGA	Head and Neck Squamous Cell Carcinoma	0.1225	0.0636	1.3e-05	0.062	0.035	0.050	NA	0.058	1.7e-07	7.3e-05	2.7e-06	NA	4.2e-07
19	TCGA	Testicular Germ Cell Tumors	0.1930	0.0970	9.5e-03	0.016	0.065	0.064	NA	0.033	8.8e-02	2.6e-03	2.7e-03	NA	2.5e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Sitting height	15.3	108.8	259.2	9.4	11.4	11.8	10.8	8.6	5.3	16.1	-7.9	10.3	11.3	11.3	7.2	-3.9	14.3	12.1	10.0	8.7	-12.7	7.2
Forced vital capacity (FVC), Best measure	6.4	23.4	42.5	3.9	6.0	5.4	5.9	1.8	3.1	6.2	1.3	6.4	6.0	6.4	4.8	3.0	6.5	4.1	5.6	0.6	-0.8	5.9
Forced vital capacity (FVC)	6.3	24.3	45.4	4.4	6.1	5.3	6.0	3.4	2.8	6.7	0.9	6.2	6.2	6.5	4.7	2.1	6.7	4.2	5.7	0.7	-1.5	5.5
Tense / ‘highly strung’	6.3	10.5	17.1	-3.7	-4.1	-2.6	-4.1	-1.4	-3.2	-2.8	-2.0	-3.8	-4.1	-4.1	-3.8	-2.3	-3.5	-3.1	-4.0	0.3	-0.2	-3.8
Type 2 Diabetes (T2D) (2012)	5.8	6.7	12.0	2.5	3.5	1.7	3.1	1.7	3.1	2.5	0.5	3.2	3.4	3.4	3.0	1.2	3.0	3.0	2.9	0.5	-0.0	2.5
Lung FVC	5.6	28.3	41.8	4.9	6.0	5.6	6.1	3.6	5.5	3.6	5.8	6.1	6.0	6.3	6.4	6.0	5.2	3.2	6.4	-0.8	3.3	6.5
Forced expiratory volume in 1-second (FEV1)	5.6	18.9	33.9	4.0	5.4	4.3	5.3	2.5	2.4	5.7	1.6	5.8	5.4	5.8	4.3	2.3	5.7	3.6	5.1	0.3	-1.1	5.1
Hand grip strength (right)	5.4	14.8	36.0	3.8	4.3	6.0	4.5	3.1	2.4	3.8	1.7	4.6	4.4	4.6	3.9	3.1	4.9	3.1	4.5	1.2	-0.6	4.1
Forced expiratory volume in 1-second (FEV1), Best measure	5.4	17.3	31.4	3.6	5.0	3.9	5.0	1.4	2.9	5.2	1.6	5.6	5.1	5.6	4.2	2.8	5.6	3.6	4.9	0.4	-0.5	5.2
Hand grip strength (left)	5.0	13.2	24.6	4.2	4.1	4.8	4.2	2.9	2.1	3.8	1.4	4.4	4.2	4.4	3.4	2.2	5.0	3.1	4.4	1.4	-1.1	4.1
Trunk fat-free mass	5.0	28.5	81.7	4.7	6.0	4.9	5.8	3.0	0.1	9.0	-2.9	5.8	6.1	6.2	3.4	-2.0	7.4	5.5	5.3	4.3	-6.3	5.2
Height	4.9	93.6	295.8	8.1	11.0	9.4	10.3	5.2	0.3	17.2	-7.4	9.5	11.0	11.4	4.6	-2.9	14.2	9.6	8.8	6.9	-12.2	8.9
Trunk predicted mass	4.9	27.9	81.0	4.6	5.9	4.9	5.8	3.0	0.1	9.0	-3.0	5.8	6.0	6.1	3.4	-2.1	7.3	5.5	5.2	4.4	-6.3	5.1
Standing height	4.5	44.5	151.3	5.5	7.6	5.5	7.1	3.0	-0.3	12.3	-5.0	7.0	7.6	7.9	3.0	-2.4	10.1	6.6	6.1	4.4	-8.1	6.2
Loneliness, isolation	4.5	6.2	10.7	-3.3	-3.0	-2.3	-3.1	-1.8	-2.6	-1.4	-1.6	-2.8	-3.0	-2.9	-3.1	-2.6	-2.6	-2.5	-3.0	0.6	-0.1	-2.2
Whole body fat-free mass	4.4	25.0	74.8	4.4	5.5	4.4	5.3	3.4	0.2	8.7	-2.9	5.4	5.6	5.7	3.2	-2.2	7.0	5.0	4.9	4.3	-6.0	4.7
Whole body water mass	4.3	24.8	74.0	4.3	5.5	4.6	5.3	3.3	0.2	8.6	-2.8	5.5	5.6	5.7	3.2	-2.1	6.9	5.0	4.9	4.2	-6.0	4.7
Arm fat-free mass (right)	4.2	21.4	61.3	3.9	5.0	4.3	5.0	2.7	-0.3	7.8	-3.0	5.1	5.1	5.3	3.1	-2.1	6.4	4.9	4.5	4.1	-5.7	4.1
Arm predicted mass (right)	4.0	20.6	62.1	3.6	4.9	4.1	4.8	2.5	-0.5	7.9	-3.1	5.0	5.0	5.1	2.9	-2.5	6.1	4.7	4.3	4.4	-5.8	4.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.9	8.2	13.6	1.8	3.0	2.4	3.1	1.0	3.4	2.4	3.2	3.6	3.0	3.3	3.2	3.7	3.3	1.6	3.2	-0.9	2.4	3.5
Loud music exposure frequency	3.8	4.2	8.0	2.4	2.4	1.9	2.4	0.7	0.8	2.7	0.5	2.5	2.4	2.7	1.9	-0.4	2.8	2.1	2.4	1.0	-1.0	2.6
Arm predicted mass (left)	3.7	18.8	55.2	3.4	4.9	4.4	4.7	2.2	-0.6	7.4	-2.5	4.8	4.9	5.0	2.8	-1.9	5.9	4.3	4.2	3.9	-5.2	4.1
Medication: Lansoprazole	3.6	4.1	7.2	-2.2	-2.1	-0.9	-2.3	-1.0	-1.8	-1.6	-2.5	-2.1	-2.2	-2.3	-2.3	-2.7	-1.9	-1.7	-2.6	1.1	-0.8	-2.6
Basal metabolic rate	3.6	19.9	60.8	3.9	4.9	4.0	4.7	3.0	-0.1	7.8	-2.6	4.9	5.0	5.0	2.9	-2.2	6.1	4.3	4.3	4.0	-5.5	4.1
Medication: Allopurinol	3.5	4.6	9.9	2.2	2.5	2.0	2.7	-0.2	3.1	1.7	0.5	2.6	2.6	2.7	2.9	0.9	2.4	2.5	2.8	0.7	-0.3	1.8
Leg predicted mass (right)	3.5	18.8	58.7	3.9	4.7	3.9	4.5	3.8	0.9	7.7	-2.5	4.5	4.7	4.7	2.9	-2.1	6.1	3.9	4.2	3.7	-5.2	3.9
Arm fat-free mass (left)	3.5	17.7	54.2	3.3	4.6	3.9	4.5	2.3	-0.7	7.4	-2.8	4.5	4.7	4.8	2.5	-2.1	5.8	4.2	4.0	3.9	-5.4	3.8
Leg fat-free mass (left)	3.4	17.9	55.4	3.7	4.5	3.5	4.3	3.7	0.6	7.4	-2.8	4.4	4.5	4.5	2.7	-2.4	5.8	4.0	3.9	3.9	-5.6	3.5
Leg predicted mass (left)	3.4	18.0	54.9	3.7	4.5	3.5	4.3	3.7	0.7	7.4	-2.9	4.5	4.5	4.5	2.8	-2.4	5.8	4.0	4.0	4.0	-5.6	3.5
Leg fat-free mass (right)	3.4	18.3	58.1	3.8	4.6	3.9	4.5	3.8	0.8	7.6	-2.5	4.5	4.7	4.7	2.8	-2.1	6.0	3.9	4.2	3.6	-5.2	3.8
Mean Putamen Volume	3.3	3.8	6.4	2.3	2.3	1.5	2.4	2.3	2.0	2.0	-0.1	1.8	2.3	2.3	2.3	1.4	2.5	2.3	2.3	0.4	-0.4	0.8
Chronic bronchitis/emphysema (father)	3.3	3.9	7.1	2.3	2.5	0.1	2.4	2.7	1.5	2.3	0.7	2.5	2.4	2.5	1.8	0.1	2.5	1.7	2.3	0.7	-0.7	2.0
Mood swings	3.3	5.9	10.1	-2.9	-3.0	-2.5	-3.0	-1.6	-1.7	-1.1	-1.8	-3.0	-3.0	-2.9	-3.2	-2.1	-2.7	-1.9	-3.1	-0.4	-0.6	-3.0
Sensitivity / hurt feelings	3.1	5.2	11.2	-3.2	-2.6	-0.2	-2.8	-1.2	-2.2	-0.5	-1.3	-3.4	-2.7	-2.7	-2.8	-2.6	-2.5	-2.0	-3.0	0.6	0.2	-2.5
Comparative height size at age 10	3.1	16.9	49.6	3.2	4.7	3.8	4.5	0.8	0.2	7.0	-2.9	4.3	4.7	5.2	2.3	-1.4	6.5	4.4	4.0	2.2	-4.5	4.1
Diastolic blood pressure, automated reading	3.0	9.2	29.8	-3.5	-3.0	-1.0	-2.9	-3.6	-1.4	-5.5	0.8	-3.1	-3.1	-3.3	-1.9	0.9	-4.2	-3.2	-3.1	-2.6	3.2	-3.3
Waist Hip Ratio (WHR)	2.8	12.6	37.7	4.4	2.8	1.7	2.7	0.3	-3.7	6.1	1.9	4.4	2.9	3.7	1.2	1.2	5.6	4.4	3.9	1.7	-0.9	5.7
Neuroticism score	2.8	5.9	9.8	-3.1	-2.8	-2.2	-2.9	-0.7	-2.6	-0.5	-2.2	-2.7	-2.8	-2.7	-3.1	-3.1	-2.5	-1.4	-3.0	0.9	-1.2	-2.8
Ever had prostate specific antigen (PSA) test	2.8	3.3	9.1	2.1	2.4	3.0	2.3	1.1	1.3	1.1	1.3	1.9	2.4	2.3	2.3	0.9	1.5	1.4	2.2	0.0	0.4	1.4
Fed-up feelings	2.7	5.0	9.2	-2.7	-2.6	-3.0	-2.6	-1.3	-2.4	-0.7	-1.8	-2.8	-2.5	-2.4	-2.6	-2.6	-2.2	-1.7	-2.7	0.6	-1.0	-2.0
Unable to work because of sickness or disability	2.7	3.5	6.4	-2.4	-2.5	-1.8	-2.5	-1.7	-1.3	-1.4	-0.3	-1.5	-2.5	-2.3	-2.2	-1.4	-2.2	-1.6	-2.3	-0.9	0.6	-1.8
Current tobacco smoking	2.6	4.2	7.3	-2.2	-2.4	-2.6	-2.5	-2.2	-2.3	-1.8	-0.9	-1.8	-2.4	-2.5	-2.7	-1.1	-2.6	-1.9	-2.3	-0.3	0.3	-1.9
Length of working week for main job	2.6	2.9	5.0	1.8	1.9	1.6	1.9	1.1	2.1	1.5	1.8	1.7	1.9	2.0	1.9	2.2	1.8	0.6	1.9	-0.7	0.6	1.6
Breast cancer (self-reported)	2.6	3.2	6.8	2.6	2.0	2.0	2.0	2.3	1.9	1.0	0.1	1.7	2.0	1.6	2.1	-0.6	1.3	2.6	2.0	1.1	-1.4	1.0
Heel T-Score	2.5	19.6	34.5	5.8	4.9	5.4	5.0	4.9	5.9	2.2	0.2	4.0	4.9	4.6	5.5	0.4	5.0	4.8	5.1	3.4	-2.7	3.4
Hearing difficulty/problems: Yes	2.5	3.8	7.5	-1.1	-2.1	-2.6	-2.3	-1.8	-0.9	-1.0	1.5	-2.1	-2.2	-2.1	-2.2	0.5	-2.2	-2.7	-1.9	-2.3	2.2	-1.6
Supplements: Zinc	2.5	2.7	7.5	0.7	2.2	0.4	2.1	-0.8	2.1	0.8	1.5	1.6	2.2	2.4	1.7	1.5	1.8	0.8	1.7	-1.2	0.6	2.7
Suffer from ‘nerves’	2.5	4.0	7.4	-2.6	-2.3	-1.8	-2.4	-0.8	-1.4	-1.3	-2.1	-2.2	-2.4	-2.7	-2.5	-2.6	-1.7	-0.3	-2.4	0.7	-1.2	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	2.3	5.2	16.2	1.9	1.8	3.1	1.9	1.4	1.5	1.7	-2.4	1.7	1.9	1.9	1.9	-2.2	2.1	2.9	1.7	3.9	-4.0	0.6
Neck or shoulder pain in last month	2.3	3.2	7.3	-1.3	-2.2	-1.9	-2.2	0.1	-1.0	-1.2	-2.1	-2.1	-2.2	-2.1	-1.5	-2.5	-1.7	-0.8	-2.1	1.2	-1.0	-2.7
Worry too long after embarrassment	2.2	3.7	7.3	-2.7	-2.1	-0.6	-2.2	-1.0	-2.2	-0.6	-2.4	-2.1	-2.1	-1.9	-2.5	-2.7	-1.5	-0.3	-2.3	1.9	-1.1	-1.9
Health satisfaction	2.2	2.9	5.5	-2.0	-2.0	-1.4	-2.2	-1.6	-0.8	-0.3	-2.2	-1.8	-2.1	-2.1	-2.0	-2.3	-0.6	-0.2	-2.0	0.8	-1.0	-1.9
Smoking status: Current	2.2	3.4	6.8	-2.0	-2.1	-2.6	-2.3	-2.0	-1.7	-1.6	-0.9	-1.6	-2.1	-2.2	-2.6	-1.1	-2.3	-1.7	-2.0	0.0	0.0	-1.5
Worry (Nagel 2018)	2.1	4.5	8.0	-2.8	-2.7	-2.3	-2.8	-0.9	-1.3	-1.9	-1.4	-2.2	-2.8	-2.8	-2.8	-1.6	-2.0	-1.4	-2.7	0.4	-0.5	-2.2
Stomach or abdominal pain in last month	2.0	2.4	5.8	-2.4	-1.9	-0.7	-1.9	-1.3	-0.9	-0.9	-0.2	-1.9	-1.9	-1.9	-1.2	-0.9	-2.2	-1.8	-1.7	-0.5	1.7	-1.4
Wheeze or whistling in the chest in last year	2.0	3.5	8.0	2.3	1.9	2.4	1.9	1.7	2.1	0.8	-1.2	1.6	1.9	1.8	2.2	-0.6	2.2	2.8	2.0	1.4	-2.4	0.9
Pulse wave peak to peak time	2.0	2.4	5.1	1.8	1.5	1.7	1.7	1.4	1.9	1.3	-0.2	1.1	1.6	1.9	1.7	0.2	2.3	2.2	1.7	1.1	-0.7	1.0
Nervous feelings	1.8	3.4	6.6	-2.1	-2.5	-1.0	-2.5	-0.5	-1.6	-1.9	-1.4	-1.7	-2.5	-2.5	-2.6	-1.6	-1.3	-1.0	-2.3	0.8	-0.7	-2.2
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	6.0	-2.4	-1.8	-1.3	-1.9	-0.2	-0.7	-1.1	-1.8	-1.9	-1.8	-1.8	-1.8	-1.9	-1.9	-1.3	-2.1	0.9	-0.9	-2.2
Pulse rate	1.7	2.9	6.0	-1.1	-2.3	-1.6	-2.1	-0.2	-2.0	-2.0	0.1	-2.2	-2.3	-2.4	-1.7	-0.3	-1.9	-1.7	-1.7	-0.5	1.2	-1.7
Medication: Gliclazide	1.7	1.9	3.5	0.2	1.3	1.8	1.2	1.8	-0.1	1.6	-0.4	1.7	1.3	1.0	1.0	-1.3	1.4	1.8	1.1	1.9	-1.6	1.8
Frequency of depressed mood in last 2 weeks	1.6	2.2	4.8	-1.9	-1.7	-1.0	-1.9	-0.4	-1.4	-0.2	-1.6	-1.8	-1.8	-1.4	-2.2	-2.0	-1.1	-0.8	-2.0	0.3	-0.7	-1.7
Weight	1.6	8.1	26.4	2.3	2.9	2.3	2.7	2.3	-1.0	5.1	-1.8	3.1	2.8	2.7	1.6	-2.4	3.6	2.5	2.5	3.3	-4.1	2.4
Number of full sisters	1.6	2.0	5.0	-1.2	-1.8	-0.8	-1.5	-1.4	-2.0	-2.2	0.9	-0.9	-1.7	-1.6	-1.3	0.2	-1.8	-1.4	-1.2	-1.2	1.3	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.3	8.3	0.9	2.3	1.6	2.2	0.5	0.3	2.4	-1.3	2.4	2.3	2.3	1.0	-0.1	2.9	1.6	1.9	1.4	-2.0	2.2
Pain experienced in last month	1.6	2.7	6.2	1.6	1.8	2.1	1.8	0.4	-0.3	2.0	-0.6	1.8	1.8	1.8	1.0	-0.3	2.5	1.9	1.6	1.9	-1.8	1.6
Schizophrenia vs Biploar Disorder	1.5	1.9	8.5	1.6	1.0	0.3	1.0	0.7	0.3	1.0	-1.6	0.8	1.0	1.0	0.5	-1.3	1.5	1.8	1.0	2.8	-2.9	0.6
Pack years adult smoking proportion	1.5	2.3	4.2	-1.9	-1.9	-1.6	-1.8	-1.4	-1.6	-0.1	-1.1	-1.2	-1.9	-1.9	-1.6	-2.1	-2.0	-0.8	-1.6	1.0	-0.3	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.5	10.3	1.2	1.5	2.6	1.6	0.6	1.4	1.7	-2.0	1.4	1.5	1.5	1.5	-1.8	1.7	2.5	1.4	3.1	-3.2	0.3
Depression (self-reported)	1.5	1.8	3.6	-1.9	-1.6	-1.8	-1.5	-1.7	-1.1	-0.3	-1.2	-1.7	-1.6	-1.5	-1.2	-1.4	-1.3	-0.9	-1.6	0.7	-0.1	-0.7
Headache pain in last month	1.5	2.6	4.8	-1.5	-2.1	-1.7	-2.1	-1.0	-1.9	-1.0	1.1	-1.3	-2.2	-2.2	-1.4	0.2	-1.7	-1.8	-1.5	-1.6	1.9	-0.9
Overall health rating	1.5	3.2	6.2	-2.4	-2.2	-1.5	-2.3	-1.6	-1.4	-1.1	-1.2	-1.1	-2.3	-2.5	-2.1	-2.5	-1.9	-1.1	-2.1	0.4	-0.4	-1.5
Back pain experienced in last month	1.5	2.2	5.0	-1.8	-1.5	-1.0	-1.4	0.2	0.6	-2.2	0.6	-1.6	-1.5	-1.6	-0.0	0.8	-2.0	-1.9	-1.2	-1.8	2.2	-1.5
Diabetes (mother)	1.4	1.7	5.7	-1.0	-0.8	-1.8	-1.0	0.2	-1.6	-0.6	-2.4	-1.5	-0.9	-0.8	-0.9	-1.9	-1.3	0.2	-1.4	1.1	-1.6	-1.7
Relative age voice broke	1.4	2.1	4.8	-2.2	-1.7	-1.7	-1.6	-1.8	-1.5	-1.4	0.4	-1.4	-1.6	-1.5	-1.9	-0.5	-1.8	-1.8	-1.7	-0.3	0.7	-0.3
Serious illness, injury or assault to yourself	1.4	1.7	3.9	1.3	1.6	0.7	1.6	0.6	1.9	1.0	0.9	1.4	1.6	1.6	1.4	0.3	1.6	2.0	1.5	-0.4	0.8	1.2
High blood pressure (siblings)	1.4	2.1	8.0	1.0	1.1	0.0	1.2	1.3	1.5	0.1	2.8	0.3	1.1	1.0	1.7	2.8	0.7	0.0	1.5	-1.2	2.2	1.4
Medication: Seretide 50 evohaler	1.4	1.6	4.4	1.2	1.6	1.1	1.7	1.0	1.6	1.1	0.0	1.3	1.6	1.5	2.1	1.1	1.4	0.6	1.3	-1.3	0.1	0.9
Leg pain on walking	1.4	1.7	5.5	-1.7	-1.7	-1.1	-1.6	-0.3	-2.4	-1.8	-0.7	-1.1	-1.7	-1.5	-1.1	-0.9	-1.4	-1.3	-1.3	0.3	0.3	-0.7
Commuting to job workplace: Cycle	1.4	1.7	4.2	-1.4	-1.6	-1.1	-1.7	-0.2	0.2	0.2	-1.5	-1.3	-1.7	-1.4	-1.4	-2.0	-0.4	-0.7	-1.6	0.9	-0.3	-2.0
Alzheimer’s Disease (in father)	1.3	1.4	5.1	-1.4	-1.1	-0.4	-1.3	0.0	-0.8	-2.2	0.4	-1.4	-1.2	-1.3	-1.2	-0.3	-1.5	-2.0	-1.2	-0.3	1.0	-0.8
Ever used hormone-replacement therapy (HRT)	1.3	1.6	8.3	-0.2	-0.1	-1.2	-0.1	-0.1	-0.1	0.4	-2.6	0.2	-0.0	-0.3	-0.5	-2.6	0.3	0.6	-0.2	2.5	-2.9	0.1
Age at last live birth	1.3	2.0	5.9	1.7	1.7	0.9	1.5	0.7	0.7	0.4	1.3	2.4	1.6	1.6	1.6	1.1	1.6	1.0	1.8	0.4	0.4	1.8
Medication for cholesterol	1.3	2.0	3.9	1.6	1.5	1.8	1.5	1.2	0.9	0.6	1.8	1.4	1.5	1.6	1.4	1.4	1.4	1.3	1.6	-0.4	1.1	2.0
Pack years of smoking	1.3	1.8	3.9	-1.8	-1.6	-1.4	-1.5	-1.2	-1.3	0.0	-1.1	-1.1	-1.6	-1.6	-1.4	-1.9	-2.0	-0.6	-1.5	1.0	-0.4	-1.1
Systolic blood pressure, automated reading	1.2	3.3	13.9	-1.7	-1.9	-0.9	-1.8	-3.0	-1.0	-3.7	-0.1	-2.2	-1.9	-2.1	-1.1	0.1	-2.3	-1.3	-1.8	0.1	1.2	-2.1
Impedance of leg (right)	1.2	5.9	15.8	-2.3	-2.5	-2.9	-2.6	-4.0	-3.0	-3.2	-0.1	-1.8	-2.6	-2.4	-2.6	0.3	-2.8	-1.7	-2.6	-1.8	1.4	-2.3
Impedance of leg (left)	1.2	5.7	14.6	-2.3	-2.4	-2.3	-2.5	-3.8	-3.0	-3.0	0.7	-1.7	-2.4	-2.3	-2.4	0.9	-2.7	-2.0	-2.4	-2.2	2.4	-1.9
Number of live births	1.2	1.7	7.0	-0.2	-1.1	-1.3	-1.0	-0.5	-2.6	-0.9	0.9	-0.6	-1.1	-0.9	-0.1	1.5	-1.0	-1.5	-0.6	-2.3	2.4	-0.7
Birth weight	1.2	2.7	8.6	1.0	1.3	0.7	1.5	2.9	1.1	1.9	-1.3	1.9	1.4	1.4	1.6	-1.0	2.2	1.6	1.4	2.4	-2.0	0.7
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.7	0.7	1.6	1.0	1.6	1.6	1.6	1.4	0.6	1.3	1.6	1.4	1.5	-0.1	0.8	0.6	1.2	-0.4	-0.3	1.3
Osteoarthritis (self-reported)	1.2	1.6	4.6	-0.8	-1.0	-2.1	-1.1	0.7	0.3	-1.7	-2.0	-1.3	-1.0	-1.3	-1.1	-1.6	-0.8	-0.5	-1.1	0.9	-1.2	-1.6
Neuroticism (Nagel 2018)	1.1	2.5	4.3	-2.0	-1.9	-1.5	-2.0	-0.8	-1.1	-0.3	-1.8	-1.9	-1.9	-1.7	-1.9	-2.1	-1.2	-0.8	-2.0	0.6	-0.9	-1.8
Breast Cancer	1.1	2.6	11.1	-0.5	0.2	-0.0	0.3	-2.1	-2.0	0.2	2.5	1.0	0.2	0.6	-0.2	2.4	0.2	-1.6	0.5	-3.3	2.3	2.6
Exposure to tobacco smoke outside home	1.1	1.4	5.3	-1.1	-1.2	-0.2	-1.2	-1.4	-0.7	-0.9	0.5	-1.2	-1.2	-1.1	-1.2	0.9	-1.4	-1.8	-1.1	-2.3	1.1	-1.1
Guilty feelings	1.1	1.6	6.5	-1.0	-1.0	-1.3	-1.0	0.3	0.2	0.7	-1.9	-1.4	-1.0	-0.9	-1.2	-2.5	-0.7	-0.4	-1.3	1.6	-1.8	-1.4
Lung cancer (father)	1.0	1.2	3.9	1.1	0.7	-0.3	0.7	1.3	0.8	1.8	-0.6	1.3	0.7	0.4	1.0	-0.8	1.2	2.0	0.8	1.3	-1.4	0.6
Pulse wave Arterial Stiffness index	1.0	1.1	3.6	-1.3	-0.9	-1.2	-1.1	-1.2	-1.9	-0.2	-0.1	-0.5	-1.0	-1.2	-1.5	-0.4	-1.3	-1.5	-1.1	-0.7	0.0	-0.4
Comparative body size at age 10	1.0	2.8	11.8	1.1	1.1	2.7	1.3	1.8	1.0	1.8	-0.9	1.7	1.1	1.1	1.8	-1.2	1.7	1.9	1.4	3.4	-1.8	0.4
Average weekly champagne plus white wine intake	1.0	1.4	4.7	0.5	1.5	1.1	1.2	-0.3	2.2	1.7	0.4	1.2	1.4	1.5	0.7	1.2	1.8	0.6	0.9	-0.4	-0.1	1.0
Commuting to job workplace: Public transport	1.0	1.2	2.7	-0.8	-1.2	-0.6	-1.3	-0.3	-1.6	0.7	-1.2	-1.2	-1.2	-1.2	-1.6	-1.5	-0.4	-0.5	-1.1	0.9	-0.9	-0.8
Supplements: Fish oil (including cod liver oil)	1.0	1.3	3.5	-1.0	-1.3	-0.5	-1.3	-0.6	-1.7	0.4	-1.9	-0.9	-1.3	-1.1	-0.8	-1.7	-0.4	0.1	-1.1	1.4	-0.6	-1.4
Illnesses of father: High blood pressure	1.0	1.3	3.0	-1.7	-1.3	0.1	-1.2	-1.6	-1.7	-0.9	0.6	-0.7	-1.2	-1.4	-0.6	0.4	-1.3	-1.1	-1.3	-1.0	1.1	-0.7
Number of operations (self-reported)	1.0	1.5	3.1	-1.2	-1.3	-1.8	-1.4	-0.7	-1.1	-0.9	0.9	-1.1	-1.3	-1.2	-0.9	-0.7	-1.6	-1.3	-1.2	-1.0	1.7	-1.0
Fractured/broken bones in last 5 years	1.0	1.3	6.4	-0.7	-1.0	-2.5	-1.0	1.2	0.3	1.1	-0.9	-1.2	-0.9	-0.9	-1.1	-1.9	-0.9	-0.7	-1.1	0.4	-0.7	-0.8
Depression (Nagel 2018)	0.9	1.3	5.6	-0.8	-0.3	-0.5	-0.4	0.3	-0.4	1.6	-2.4	0.1	-0.2	-0.2	-0.9	-2.2	0.4	0.7	-0.7	1.7	-2.4	-0.3
Neuroticism	0.9	2.1	6.2	-1.3	-1.6	-1.5	-1.6	0.2	-1.5	-0.2	-1.6	-1.6	-1.6	-1.5	-1.5	-2.5	-1.2	-0.4	-1.6	0.5	-1.2	-2.2
Vitamin and mineral supplements	0.9	1.2	2.4	1.1	1.2	0.7	1.4	-0.5	0.7	1.0	0.9	1.3	1.4	1.3	1.0	1.4	1.1	0.8	1.3	-0.5	0.3	1.6
Severe depression (siblings)	0.9	1.1	3.1	0.3	0.5	0.1	0.5	1.5	0.9	1.4	-0.7	1.4	0.5	0.3	0.6	-1.3	0.7	1.6	0.6	1.6	-1.8	0.7
Townsend deprivation index at recruitment	0.9	1.3	4.7	-0.9	-0.8	-1.2	-1.0	-1.1	-0.5	-1.2	1.0	-0.9	-0.8	-1.0	-1.4	0.2	-1.6	-1.7	-1.0	-2.2	1.3	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.1	5.5	-1.7	-0.8	0.2	-0.9	-0.4	-0.6	-0.2	-1.4	-0.3	-0.8	-1.0	-1.2	-2.3	-0.8	-0.5	-1.1	1.0	-1.7	-0.4
Waist circumference	0.9	3.3	10.6	1.2	1.2	0.9	1.1	1.4	-2.6	3.3	-0.6	1.8	1.2	1.1	0.5	-1.9	1.9	1.6	1.3	3.0	-2.5	2.1
Fluid intelligence score	0.9	1.8	6.0	1.0	1.3	1.7	1.4	-0.9	1.2	-0.5	2.5	1.0	1.4	1.1	1.1	1.5	0.7	0.7	1.4	-1.0	1.7	1.8
Qualifications: A levels/AS levels or equivalent	0.9	2.0	4.3	1.8	1.4	0.2	1.4	2.1	1.6	2.0	-0.0	1.6	1.4	1.2	1.8	0.7	2.1	1.0	1.7	0.4	-0.5	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	3.7	-1.6	-1.1	-1.5	-1.1	-1.7	-1.0	-0.9	-0.6	-0.5	-1.1	-1.2	-0.9	-1.9	-1.6	-0.4	-1.1	1.3	-0.4	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.2	-1.0	-1.3	-1.3	-1.3	0.1	-0.8	-0.9	-1.3	-1.2	-1.3	-1.5	-1.1	-0.9	-0.9	-0.0	-1.2	0.2	-0.6	-1.2
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	6.0	-1.2	-0.9	1.1	-0.8	0.5	-0.8	-2.5	-0.4	-1.4	-0.8	-0.9	-0.9	-0.2	-1.4	-1.5	-1.1	0.3	-0.1	-0.9
Ever had bowel cancer screening	0.9	1.0	3.2	1.4	1.1	1.8	1.1	0.9	0.3	0.5	0.1	1.0	1.1	1.3	1.4	0.6	1.2	0.7	1.1	1.0	-0.1	0.4
Miserableness	0.9	1.5	5.2	-1.3	-1.3	-1.0	-1.2	0.0	-0.5	1.4	-0.9	-1.6	-1.3	-1.1	-1.2	-2.3	-1.0	-0.8	-1.3	0.6	-0.6	-1.7
Age started oral contraceptive pill	0.9	1.1	7.6	-0.2	0.2	-0.0	0.3	-0.6	1.1	0.4	-2.8	-0.3	0.2	0.6	-0.2	-1.0	1.0	0.8	-0.3	1.7	-2.1	-0.8
Cholesterol lowering medication	0.9	1.4	5.6	-0.5	-0.9	-0.4	-0.8	-0.2	-0.6	-0.7	-2.4	-1.1	-0.9	-0.9	-0.4	-1.9	-1.1	0.0	-0.9	1.4	-1.7	-2.1
Alcohol drinker status: Previous	0.9	1.0	4.5	1.0	0.3	-0.8	0.3	2.1	1.0	0.1	-1.2	0.1	0.3	0.3	0.1	-1.5	1.1	1.4	0.6	1.2	-1.5	0.5
Depressed Affect (Nagel 2018)	0.8	1.6	4.7	-1.2	-1.4	-2.2	-1.2	-0.2	-0.9	1.0	-1.8	-1.5	-1.3	-1.1	-1.1	-1.9	-0.9	-0.5	-1.3	0.8	-1.1	-1.5
Reaction Time	0.8	1.5	4.0	-2.0	-1.3	-0.1	-1.3	-0.7	-1.9	-0.9	-1.6	-1.0	-1.3	-1.5	-1.4	-0.9	-1.1	-0.7	-1.5	0.8	-0.5	-1.4
LDL Cholesterol	0.8	1.2	4.5	1.0	1.0	1.0	1.1	-0.2	0.8	-0.1	2.1	0.7	1.1	0.9	0.6	1.4	0.5	0.6	1.1	-1.8	1.4	1.4
Schizophrenia (2014)	0.8	1.8	6.7	0.5	-0.6	-1.6	-0.7	2.0	-0.5	0.5	-2.2	-0.1	-0.8	-0.1	-0.4	-2.0	0.7	1.6	-0.4	2.5	-2.6	-0.9
Ever had hysterectomy (womb removed)	0.8	0.9	5.5	-0.9	-0.7	-0.9	-0.6	-1.1	-1.8	-0.3	1.4	-0.2	-0.7	-0.6	-0.0	-0.0	-0.8	0.3	-0.1	-0.5	2.4	0.4
Bilateral oophorectomy (both ovaries removed)	0.8	1.0	2.8	0.2	-0.4	-1.7	-0.5	1.2	-1.2	0.6	-1.6	-0.3	-0.4	-0.5	-0.6	-1.7	0.2	0.5	-0.3	1.6	-1.6	-0.4
Heart attack	0.8	1.0	4.8	0.5	0.3	2.2	0.4	1.6	0.7	0.3	1.2	-0.0	0.3	0.6	1.1	1.0	0.6	0.7	0.7	-0.4	2.0	0.4
Medication: Ramipril	0.8	1.0	5.0	0.2	-0.0	0.3	0.1	0.3	-0.7	-0.6	2.2	-0.9	-0.0	-0.1	0.7	1.8	-0.5	-0.5	0.4	-1.5	2.2	0.5
Illnesses of mother	0.8	1.0	2.7	-0.9	-1.0	-0.7	-0.9	-1.4	-0.7	-1.6	0.5	-1.1	-1.0	-0.8	-1.1	0.2	-0.9	-1.6	-0.9	-1.4	1.1	-0.4
Birth weight of first child	0.8	1.4	6.2	1.5	0.8	0.6	1.0	1.6	0.1	2.5	0.0	1.4	0.9	1.1	1.1	-0.2	1.8	1.0	1.3	1.1	-0.7	1.3
Age at first live birth	0.8	1.4	3.0	1.4	1.3	1.4	1.3	0.4	0.7	-0.6	1.5	1.7	1.2	1.4	1.5	1.4	0.9	0.7	1.4	-0.6	0.7	1.3
Hearing aid user	0.8	0.9	2.1	-1.2	-0.7	-0.7	-0.7	-0.8	0.3	-0.4	-1.4	-1.1	-0.7	-1.0	-1.1	-1.4	-0.9	-0.4	-1.1	1.0	-1.2	-0.9
Mother’s age at death	0.8	0.9	3.2	1.3	0.9	0.8	0.9	-0.7	1.0	-0.1	1.5	0.6	0.9	0.8	0.8	1.8	0.6	0.7	1.1	-0.7	1.0	1.0
Financial situation satisfaction	0.8	1.0	2.3	-1.2	-1.2	-0.6	-1.2	-1.0	-1.5	-1.2	-0.5	-0.7	-1.2	-1.1	-1.2	-0.7	-1.4	-0.3	-1.1	0.9	0.0	-0.5
Heart attack/myocardial infarction (self-reported)	0.8	1.0	5.1	0.4	0.3	2.3	0.5	1.7	0.7	0.5	1.2	0.1	0.3	0.7	1.2	1.0	0.6	0.5	0.7	-0.3	2.0	0.4
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	3.4	-1.0	-0.9	-1.4	-1.0	-1.1	-1.2	-0.6	0.5	-0.9	-1.0	-1.2	-1.0	0.5	-1.2	-1.8	-1.1	-0.9	0.8	-0.3
Impedance of whole body	0.8	3.9	6.1	-1.9	-2.1	-2.3	-2.3	-2.1	-1.2	-2.5	-0.1	-1.9	-2.2	-2.2	-2.2	0.4	-2.2	-1.8	-2.3	-2.1	1.6	-2.3
Crohns Disease (2017)	0.7	1.6	7.9	0.9	0.8	0.0	1.0	1.8	0.9	1.4	-1.5	1.0	1.1	1.1	0.3	-1.2	1.5	1.5	0.7	1.1	-2.8	0.4
Neuroticism (2016)	0.7	1.0	3.1	-1.3	-1.2	-0.3	-1.2	-0.7	-1.1	0.2	-0.6	-0.9	-1.3	-1.3	-1.3	-1.8	-0.9	-0.1	-1.2	1.1	-0.7	-0.6
Respiratory disease	0.7	1.5	6.2	1.2	1.1	1.5	1.3	1.8	2.5	0.9	-1.0	0.5	1.2	1.2	1.3	-0.1	1.5	1.2	1.0	-0.8	-1.0	0.1
Medication for hormone replacement therapy	0.7	0.8	4.3	-1.0	-0.9	-2.1	-1.1	0.1	-0.7	-0.0	0.3	-0.3	-1.0	-1.0	-1.0	0.1	-0.3	-1.6	-0.9	-0.2	0.6	0.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	6.6	0.3	0.2	-0.4	0.1	2.6	0.6	0.7	-0.9	0.3	0.1	-0.2	0.1	-1.1	0.9	0.6	0.3	1.9	-0.9	-0.3
Qualifications: None of the above	0.7	1.4	3.4	-1.6	-1.3	-1.8	-1.2	-1.7	-1.2	-1.4	-0.3	-0.6	-1.2	-1.4	-1.2	-0.6	-1.9	-0.9	-1.3	0.2	-0.1	-0.9
Pain all over the body in last month	0.7	0.7	4.5	0.8	0.4	-0.9	0.4	0.7	1.1	-0.3	-0.9	0.3	0.5	0.4	-0.1	-1.2	0.5	1.2	0.3	1.0	-2.1	0.2
Medication: Cholesterol lowering	0.7	1.1	3.8	0.4	0.9	1.2	1.1	1.2	1.6	1.0	0.9	0.2	1.0	1.2	1.9	1.0	0.8	0.7	1.0	0.3	1.1	1.0
Medication: Ventolin 100micrograms inhaler	0.7	1.0	3.4	-0.8	-1.3	-0.6	-1.2	0.4	-0.2	-0.7	-0.9	-1.8	-1.3	-1.1	-1.3	-1.1	-0.6	-0.6	-1.3	0.2	-0.3	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.2	-0.4	-0.4	-1.1	-0.5	-1.0	-1.3	-0.2	1.2	-0.0	-0.5	-0.4	-0.2	0.4	-0.8	-1.4	-0.4	-1.5	1.3	-0.1
Medication: Blood pressure	0.7	1.4	3.4	-1.5	-1.1	-0.7	-1.1	-1.6	-0.1	-1.3	-1.0	-1.5	-1.1	-1.2	-1.0	-0.4	-1.5	-1.2	-1.3	-0.2	-0.2	-1.8
Ever smoked	0.7	1.3	7.8	-1.0	-1.3	-0.8	-1.4	-0.3	-2.8	-0.7	0.4	-0.5	-1.3	-1.4	-1.3	-0.6	-1.3	-1.0	-0.9	-0.2	1.2	-0.5
Heart disease (siblings)	0.7	0.9	3.2	-1.3	-0.9	-0.5	-0.6	0.2	-1.2	-1.2	-0.7	-0.9	-0.7	-1.0	-0.2	-1.5	-1.8	-0.3	-0.8	0.9	-0.1	-1.2
Intelligence (Savage-Jansen 2018)	0.6	1.7	7.7	1.2	1.1	0.1	1.2	0.1	0.6	-0.9	2.8	0.5	1.2	0.9	1.3	1.7	0.2	0.2	1.4	-2.0	2.1	1.5
Schizophrenia (2018)	0.6	1.3	5.3	0.3	-0.8	-1.3	-0.7	1.2	-0.4	0.1	-2.0	-0.0	-0.8	-0.2	-0.3	-1.7	0.3	1.1	-0.4	2.1	-2.3	-0.9
Verbal and Numeric Reasoning (VNR)	0.6	1.3	5.4	0.7	0.5	0.9	0.7	-0.3	1.1	-1.6	2.2	0.2	0.6	0.4	0.8	1.9	0.1	-0.1	0.8	-2.0	2.3	0.5
Bipolar Disorder (2011)	0.6	0.5	2.5	-0.5	-0.0	-0.1	-0.1	-1.2	0.4	-0.6	1.6	0.4	-0.1	-0.0	-0.0	0.7	-1.0	-0.9	-0.1	-0.8	1.5	0.4
HbA1C	0.6	0.6	1.5	-0.6	-0.9	-0.8	-1.1	0.5	-0.1	0.2	-0.5	-1.1	-1.0	-0.8	-1.2	-1.1	-0.4	-0.1	-0.9	-1.0	-0.2	-0.7
Rheumatoid Arthritis	0.6	0.8	2.6	1.0	0.8	-0.5	0.9	0.0	0.1	0.7	1.1	0.7	0.8	1.0	1.5	1.6	0.9	-0.3	1.0	-0.5	0.8	0.9
Chronotype (morning person)	0.6	1.3	3.8	1.3	1.0	0.1	1.0	1.8	1.6	0.9	1.6	0.7	0.9	1.1	1.0	0.8	1.4	-0.1	1.3	0.3	0.8	1.9
Angina	0.6	0.8	4.5	0.9	0.7	0.2	0.7	0.9	2.1	0.3	-0.4	-0.0	0.7	1.0	1.4	0.4	1.0	1.3	0.7	0.0	0.5	-0.5
Diabetes (father)	0.6	0.7	2.4	0.2	1.0	0.4	1.0	0.8	0.9	1.5	-0.7	0.9	1.0	1.1	1.0	0.2	1.1	0.5	0.8	0.5	-0.8	0.6
Impedance of arm (right)	0.6	2.9	5.1	-1.1	-1.9	-2.1	-2.0	-1.0	-0.2	-2.2	0.7	-1.8	-2.0	-2.0	-1.9	0.7	-1.8	-1.8	-1.8	-2.2	1.8	-1.8
Alcohol intake versus 10 years previously	0.6	0.8	2.9	1.2	0.8	-1.6	0.7	0.6	-0.1	0.7	-0.2	0.9	0.8	1.0	0.6	-0.6	0.8	1.7	0.8	0.7	-1.2	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	4.9	-0.6	-0.6	-0.3	-0.7	0.2	0.5	1.1	-1.5	-0.8	-0.6	-0.5	-1.2	-2.2	0.5	0.0	-0.7	0.8	-1.8	-0.4
Exposure to tobacco smoke at home	0.6	0.6	1.7	0.5	1.0	0.3	0.9	1.0	1.2	0.7	0.8	1.0	1.0	0.8	0.5	0.9	0.4	-0.1	0.8	-0.9	1.3	0.4
Leg fat percentage (right)	0.6	2.3	8.0	-0.9	-1.6	-1.7	-1.6	-0.5	-2.8	-2.0	0.6	-0.5	-1.6	-2.0	-0.8	-1.4	-2.5	-1.4	-1.3	1.2	-0.1	-1.3
Number of full brothers	0.6	0.8	4.4	0.1	-0.7	-0.2	-0.5	0.4	-2.1	-0.1	1.2	0.4	-0.6	-0.5	-0.3	0.9	-0.2	-0.9	-0.1	-1.9	1.4	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.8	3.3	0.3	0.6	0.2	0.5	0.1	1.2	0.8	-0.8	0.5	0.5	0.6	0.1	-0.3	1.6	1.1	0.3	1.2	-1.8	1.1
Shortness of breath walking on level ground	0.6	0.7	2.2	-1.2	-0.8	0.1	-0.7	-0.9	-0.7	-1.3	0.4	-1.0	-0.8	-0.4	-0.3	1.1	-0.7	-1.0	-0.7	-0.8	1.5	0.2
Angina (self-reported)	0.6	0.7	3.7	0.8	0.7	0.5	0.8	0.7	1.9	0.2	-0.3	0.2	0.7	1.0	1.4	0.4	1.0	1.3	0.7	0.1	0.5	-0.4
Mean time to correctly identify matches	0.6	1.1	2.5	-1.6	-0.8	0.4	-0.8	-1.1	-1.4	-1.0	-1.5	-0.6	-0.8	-1.0	-0.8	-0.8	-1.1	-0.2	-1.1	1.4	-0.8	-1.0
Chest pain or discomfort	0.6	0.9	1.8	1.3	0.7	0.6	0.8	1.4	0.8	0.9	-0.6	0.5	0.8	0.6	1.1	-1.0	1.0	1.2	1.1	1.3	-1.3	0.5
Family relationship satisfaction	0.6	0.7	2.8	0.4	0.4	1.1	0.4	1.2	0.5	1.1	0.3	0.6	0.4	0.3	0.6	-0.2	0.5	1.3	0.6	1.7	-1.2	1.0
Supplements: Vitamin C	0.6	0.8	1.9	0.5	1.2	1.4	1.1	0.6	0.4	0.7	0.2	1.0	1.1	1.2	1.4	-0.2	1.2	0.3	0.9	-0.2	0.2	0.7
Wears glasses or contact lenses	0.6	0.6	1.9	1.1	1.1	0.0	1.0	1.2	0.8	0.2	0.2	0.1	1.0	0.9	0.9	-0.2	0.6	1.4	0.9	0.4	-0.4	0.9
Ever taken oral contraceptive pill	0.6	0.6	2.4	-0.1	-0.4	-0.3	-0.4	0.7	0.2	1.1	-1.5	-0.2	-0.4	-0.4	-1.0	-1.2	0.6	0.3	-0.4	1.1	-1.5	-0.8
Medication: Atorvastatin	0.6	0.8	4.4	0.3	0.5	0.6	0.6	-0.2	-0.0	0.9	1.4	0.1	0.5	1.0	1.1	1.8	0.3	0.2	0.6	-0.3	2.1	0.7
Alcohol drinker status: Never	0.6	0.7	4.0	-0.6	-0.7	0.7	-0.7	0.1	0.4	-1.1	0.8	-0.7	-0.7	-0.6	-0.6	0.7	-0.3	-1.1	-0.6	-2.0	1.2	-0.4
Myopia	0.6	0.9	2.7	1.1	1.0	1.6	1.0	0.6	1.1	0.3	0.4	0.8	1.0	0.8	0.9	1.4	0.8	0.4	0.8	-1.6	0.8	0.2
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.0	-0.0	-0.9	-0.6	-0.7	0.9	0.4	-1.4	-0.1	-1.0	-0.8	-0.9	0.2	1.0	-0.4	-1.2	-0.5	-0.9	1.1	-1.0
Basal cell carcinoma (self-reported)	0.6	0.7	3.6	-0.0	0.7	0.9	0.6	-0.9	-0.6	0.9	1.0	1.2	0.7	0.9	-0.1	0.6	0.7	0.4	0.6	-0.8	0.1	1.9
Bipolar Disorder or Schizophrenia	0.5	1.1	4.6	-0.0	-1.0	-2.1	-1.0	1.2	-0.3	-0.2	-1.4	-0.1	-1.1	-0.6	-0.3	-1.5	-0.0	1.0	-0.6	1.7	-1.2	-1.3
Ovarian Cancer	0.5	0.7	3.5	-0.0	-0.5	-0.6	-0.5	0.5	-1.2	1.2	-1.3	-0.7	-0.5	-0.3	-0.8	-1.2	-0.1	-0.4	-0.6	0.5	-0.3	-1.9
Age at First Birth	0.5	0.7	1.7	0.9	0.9	0.9	1.0	0.5	0.6	-1.3	1.0	0.5	1.0	0.9	0.5	1.3	0.3	0.5	0.8	-0.6	0.2	0.4
Body Mass Index (BMI) (2010)	0.5	0.6	2.6	1.0	0.6	1.6	0.7	1.2	0.4	0.2	0.2	1.2	0.6	0.4	1.1	-0.8	0.5	1.0	0.9	0.8	0.1	0.1
Primary Biliary Cirrhosis	0.5	0.8	2.6	-0.3	-1.1	1.1	-0.9	0.8	-0.3	0.8	-1.2	-0.2	-1.0	-0.9	-0.2	-1.2	0.2	0.6	-0.6	1.2	-0.2	-1.6
Number of treatments/medications taken	0.5	0.8	4.6	-0.4	-0.5	0.2	-0.4	-0.8	0.4	-0.6	-1.7	-0.6	-0.5	-0.5	0.2	-2.1	-0.1	0.8	-0.4	1.4	-1.6	-0.9
Medication: Metformin	0.5	0.7	4.4	-0.9	-0.2	-0.2	-0.2	0.3	-0.9	0.6	-1.6	-0.9	-0.2	-0.0	-0.4	-1.4	0.0	0.5	-0.4	2.1	-1.1	0.3
Average weekly fortified wine intake	0.5	0.6	2.6	1.3	0.1	1.5	0.3	1.6	0.2	0.2	0.5	0.8	0.1	0.2	1.1	0.6	0.9	0.3	0.9	-0.4	0.3	0.5
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	3.2	-0.1	0.0	-0.3	-0.1	1.6	0.7	0.3	-1.2	0.4	0.0	0.0	-0.1	-0.9	0.7	0.7	-0.0	1.8	-0.8	-0.2
Trunk fat mass	0.5	2.2	6.6	1.0	0.8	0.9	0.7	1.9	-1.7	2.6	-1.2	1.4	0.8	0.5	0.5	-2.4	1.1	0.9	0.8	2.5	-2.4	0.3
Allergy	0.5	1.1	3.9	-0.4	-1.3	-0.4	-1.2	-1.5	-2.0	-1.3	0.5	-0.8	-1.3	-1.2	-0.7	0.0	-1.2	-0.5	-0.7	-0.0	1.2	-0.8
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	4.3	-0.4	-0.6	-0.2	-0.6	2.1	-0.1	-0.2	-0.9	-0.3	-0.6	-0.7	-0.3	-1.7	-0.7	-0.3	-0.5	0.7	-0.3	-0.3
Time employed in main current job	0.5	0.6	3.1	0.6	0.3	0.5	0.4	1.0	0.3	0.8	-0.9	0.4	0.3	0.3	0.5	-1.8	0.5	1.0	0.4	0.6	-1.2	-0.2
Falls in the last year	0.5	0.7	5.8	-0.3	-0.6	-2.4	-0.7	-0.8	0.4	-0.7	-0.2	-0.7	-0.7	-0.3	-0.5	-0.2	-0.5	-0.3	-0.6	-1.2	0.4	-1.1
Happiness	0.5	0.7	1.5	-0.7	-1.2	-0.6	-1.2	-0.2	-0.5	-0.9	-0.1	-1.2	-1.2	-1.1	-1.0	-0.9	-0.2	0.1	-0.7	1.0	-0.5	-0.4
Noisy workplace	0.5	0.6	3.0	-0.5	-0.6	-0.6	-0.4	-0.2	0.2	-1.7	0.6	-0.5	-0.5	-0.5	-0.4	0.6	-1.5	-1.2	-0.6	-1.1	0.8	-0.4
Impedance of arm (left)	0.5	2.5	4.4	-1.2	-1.8	-2.0	-1.9	-0.6	0.4	-1.9	-0.0	-1.7	-1.9	-2.0	-1.6	0.4	-1.6	-1.6	-1.8	-2.0	1.5	-2.1
Blood clot in the leg (DVT)	0.5	0.6	2.5	-0.7	-0.5	-1.2	-0.7	-0.7	-1.0	-0.4	0.4	-0.7	-0.6	-0.8	-0.8	0.6	-0.9	-1.6	-0.9	-0.6	0.4	-0.0
Medication: Amlodipine	0.5	0.7	2.8	-0.6	-0.3	-0.7	-0.3	0.8	0.5	-0.7	-1.4	-0.8	-0.3	-0.5	0.0	-1.7	-0.7	-0.5	-0.4	1.4	-0.8	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	3.5	-0.2	-0.4	-1.1	-0.4	0.3	0.1	1.2	-1.1	-0.0	-0.5	-0.3	-0.1	-1.4	0.4	1.0	-0.2	1.9	-1.2	-0.4
Qualifications: College or University degree	0.5	1.6	5.2	1.4	1.2	-0.0	1.1	1.7	2.3	1.9	0.4	1.3	1.2	1.3	0.6	1.2	1.8	0.5	1.1	-0.8	0.2	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.3	-0.8	-0.7	-0.7	-0.7	-0.3	0.3	-0.7	0.7	-0.2	-0.7	-0.5	-0.3	0.8	-0.3	-1.5	-0.6	-1.3	1.3	-0.3
Illnesses of siblings: Diabetes	0.5	0.6	1.5	1.0	0.8	0.8	0.9	1.0	0.4	0.5	0.4	0.7	0.8	0.8	1.2	-0.5	0.9	1.2	1.0	0.1	-0.2	0.5
Average weekly red wine intake	0.5	0.7	3.0	-0.2	-0.1	0.1	-0.1	1.7	-0.9	0.5	-1.3	-0.6	-0.0	-0.5	-0.6	-1.2	-0.0	0.3	-0.3	1.6	-1.5	0.1
Diabetes diagnosed by doctor	0.5	0.8	3.9	-0.7	-0.5	-0.1	-0.5	0.7	-0.9	1.1	-1.5	-0.6	-0.5	-0.4	-0.3	-1.8	0.1	0.5	-0.4	2.0	-0.9	-0.4
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.2	0.5	-0.3	-0.7	-0.1	1.4	0.0	0.6	-1.5	-0.1	-0.3	-0.2	0.9	-0.8	0.2	1.0	0.1	0.6	-1.2	-1.1
Medication: Bendroflumethiazide	0.5	0.8	3.7	-0.7	-0.6	-0.4	-0.6	0.2	-0.8	0.3	-1.6	-0.1	-0.6	-0.9	-0.3	-1.7	-0.9	0.2	-0.5	0.4	-1.1	-1.9
Leg fat percentage (left)	0.5	2.0	7.9	-0.9	-1.4	-1.2	-1.5	-0.3	-2.8	-1.8	0.9	-0.4	-1.5	-1.9	-0.7	-1.3	-2.2	-1.4	-1.1	1.2	0.2	-1.1
Ever depressed for a whole week	0.5	0.7	4.5	0.1	-0.7	-2.1	-0.6	0.1	1.1	-1.2	-0.2	-1.3	-0.7	-0.6	-0.4	-0.4	-0.4	-0.7	-0.4	-0.4	-0.3	-0.6
Alzheimer’s Disease (including proxy)	0.4	0.6	2.6	-0.9	-0.2	0.2	-0.3	0.1	-0.3	-1.6	0.9	-0.5	-0.3	-0.3	-0.1	1.2	-1.1	-1.2	-0.4	-0.5	1.1	-0.3
Crohns Disease (2012)	0.4	0.6	3.3	0.3	0.2	-0.2	0.1	1.8	0.4	1.0	-1.0	0.2	0.2	0.1	-0.4	-0.9	0.8	0.8	0.0	1.2	-1.4	-0.1
Fasting Glucose	0.4	0.5	1.6	-0.1	-1.1	-0.1	-1.0	0.2	-0.7	0.5	-0.5	-0.1	-1.0	-0.9	-0.6	-0.6	-0.8	-0.4	-0.6	-0.7	0.2	-1.3
Systolic Blood Pressure	0.4	1.9	11.3	-1.4	-1.0	-1.1	-0.9	-3.4	-1.0	-3.0	0.7	-1.2	-1.0	-1.2	-0.4	0.2	-1.7	-0.7	-0.9	0.5	1.2	-0.6
Allergy or Eczema	0.4	1.0	4.2	0.2	0.8	-0.1	0.9	1.3	2.0	1.5	-1.4	0.3	0.8	0.8	0.9	-0.8	1.1	1.1	0.5	1.0	-1.1	0.0
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.6	0.3	0.7	0.6	0.8	-0.1	-0.1	1.5	-0.4	0.5	0.8	0.8	0.4	-1.0	0.8	1.5	0.7	1.6	-0.5	0.6
Medication: Co-codamol	0.4	0.4	1.3	1.0	0.4	-1.1	0.5	-0.4	0.9	-0.7	0.2	0.6	0.4	0.5	0.6	0.6	0.5	1.0	0.6	-0.7	0.0	0.7
Supplements: Glucosamine	0.4	0.5	1.1	0.7	0.9	0.5	0.9	-0.3	0.0	0.6	0.1	0.5	0.9	1.0	0.9	0.3	1.0	0.7	0.8	0.7	-0.2	1.0
Number of incorrect matches in round	0.4	0.7	3.3	-0.1	-0.6	-0.7	-0.4	-1.2	-0.2	-0.3	-1.4	0.1	-0.5	-0.4	-0.4	-1.8	-0.5	1.0	-0.2	1.0	-1.4	-0.5
Hair/balding pattern: Pattern 2	0.4	0.5	1.8	0.0	-0.1	1.1	0.3	-1.4	1.0	-0.9	0.5	-0.8	0.0	0.6	0.8	1.0	0.3	0.8	0.1	-0.4	1.0	-0.3
Mouth/teeth dental problems	0.4	0.7	4.9	-0.6	0.3	-0.5	0.2	-0.8	1.6	-0.5	0.7	-0.3	0.3	0.3	-0.2	1.0	-0.2	-0.6	-0.3	-2.2	1.2	0.1
Illnesses of siblings	0.4	0.5	2.2	-0.4	-0.5	-0.4	-0.8	-1.1	0.2	-0.1	-1.3	-0.2	-0.6	-0.3	-1.5	-0.9	0.0	-0.1	-0.9	0.6	-1.2	-0.3
Father’s age at death	0.4	0.6	2.1	-0.6	-0.7	-0.0	-0.7	-0.1	-0.6	-1.3	0.7	-0.9	-0.7	-1.0	-0.8	-0.3	-1.4	-0.7	-0.7	-0.9	0.2	-0.4
Worrier / anxious feelings	0.4	0.7	1.5	-1.2	-1.0	-0.8	-1.1	0.1	0.3	-0.7	-0.5	-1.0	-1.0	-0.9	-1.2	-1.0	-0.7	-0.4	-1.2	0.4	-0.9	-0.7
Hair/balding pattern: Pattern 3	0.4	0.6	2.3	-0.1	-0.8	-1.5	-0.9	-0.3	-0.7	-0.2	-1.1	-0.3	-0.8	-1.2	-1.1	-0.8	-0.2	0.0	-0.6	0.8	-0.8	-0.3
Prospective memory result	0.4	0.5	1.4	-0.3	-0.5	0.1	-0.6	-0.4	-1.0	-0.2	0.9	-0.4	-0.6	-0.4	-0.6	1.1	-0.5	-1.2	-0.2	-1.2	1.2	1.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	3.0	0.5	0.7	0.2	0.7	1.7	1.6	1.2	0.0	0.7	0.6	0.9	1.1	0.4	1.0	-0.1	0.7	-0.3	0.7	0.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	3.1	-0.2	-0.8	-0.4	-0.9	-1.2	-1.7	-0.6	-0.1	0.1	-0.8	-0.9	-1.8	-0.4	-0.6	-0.7	-0.7	-0.2	-0.4	-0.1
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.0	-0.0	0.4	1.4	0.3	0.5	-0.4	0.9	-1.2	0.4	0.3	0.3	0.1	-0.6	0.4	0.1	0.1	1.1	-1.4	-0.2
Whole body fat mass	0.4	1.7	5.5	0.8	0.9	0.8	0.8	1.6	-1.5	2.1	-0.7	1.4	0.8	0.5	0.7	-2.1	0.8	0.7	0.8	2.3	-2.1	0.4
Pulse rate, automated reading	0.4	1.4	2.6	-0.5	-1.3	-0.2	-1.5	1.2	-1.5	-1.4	-0.9	-1.2	-1.4	-1.6	-1.5	-1.0	-0.8	-0.8	-1.2	0.1	-0.5	-1.6
Commuting to job workplace: Car/motor vehicle	0.4	0.4	3.1	0.4	0.2	-0.0	0.2	-0.5	0.5	-1.3	0.8	0.0	0.2	0.2	0.4	1.8	-0.2	-0.1	0.3	-0.9	0.6	-0.1
Hypertension (Self-reported)	0.4	1.0	3.0	-0.7	-0.6	-0.8	-0.5	-1.6	-0.1	-1.6	0.9	-1.4	-0.7	-0.8	0.4	0.7	-1.4	-0.4	-0.6	-1.0	1.7	-1.3
Illnesses of father: Heart disease	0.4	0.6	2.4	0.3	0.7	0.4	0.8	0.3	-0.1	0.7	-0.5	0.8	0.7	0.9	0.7	-1.4	0.1	0.5	0.5	1.6	-1.4	0.2
Smoking status: Previous	0.4	0.6	4.3	0.3	0.2	0.6	0.1	2.1	-1.1	0.9	-0.6	0.4	0.1	-0.1	0.1	-1.5	0.3	0.3	0.3	1.1	-0.4	-0.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	3.9	0.2	0.4	0.1	0.3	0.1	-0.7	0.5	2.0	0.2	0.3	0.3	-0.3	1.0	-0.3	-0.5	0.4	-1.1	1.0	1.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.8	0.8	0.6	1.3	0.7	-0.7	-0.1	0.2	1.3	0.8	0.6	0.7	0.9	0.9	0.7	0.6	0.9	0.8	0.6	0.5
Mineral and other dietary supplements	0.4	0.5	3.6	0.4	0.0	-0.2	-0.0	0.5	0.5	-0.5	1.3	-0.1	-0.0	-0.2	-0.0	1.1	-0.4	-0.8	0.1	-1.9	1.0	0.2
Medication: Paracetamol	0.4	0.6	3.0	-0.9	0.1	1.7	0.1	-1.1	-1.2	0.1	-0.7	0.7	0.1	-0.0	-0.1	-1.6	-0.5	0.1	-0.1	0.5	-1.0	0.1
Supplements: Calcium	0.4	0.5	2.0	-0.1	0.2	-0.1	0.2	0.6	0.5	0.3	-1.4	-0.7	0.2	0.3	0.4	-0.9	0.3	0.9	-0.3	1.4	-1.1	-0.8
Bipolar Disorder (2018)	0.3	0.4	3.3	-0.5	-0.7	-1.8	-0.6	0.4	0.0	-0.4	0.2	-0.2	-0.7	-0.5	-0.2	-0.2	-0.4	0.2	-0.5	0.1	0.9	-1.1
Alzheimer’s Disease (in mother)	0.3	0.4	1.6	0.5	0.6	1.3	0.7	0.7	-0.6	-0.2	0.2	0.9	0.6	0.8	0.9	0.8	0.2	0.4	0.8	0.1	-0.0	0.2
Lupus	0.3	0.5	2.7	-0.6	0.6	1.6	0.5	-0.2	-0.2	-0.0	1.2	0.5	0.6	0.5	0.9	0.7	-0.0	-0.0	0.4	-0.4	1.1	0.5
Ulcerative Colitis	0.3	0.5	3.7	-0.6	-0.5	0.1	-0.5	0.1	-0.0	-0.5	0.8	-0.5	-0.5	-0.3	-0.1	0.8	-0.5	-0.8	-0.5	-1.2	1.9	0.0
Smoking Status	0.3	0.6	1.9	-0.7	-0.8	-0.7	-0.9	-0.0	-1.1	-0.3	-0.7	-0.4	-0.9	-1.0	-1.1	-1.0	-1.1	-0.4	-0.6	0.0	0.3	-1.4
Hypothyroidism (self reported)	0.3	0.6	2.2	1.4	0.3	-0.4	0.5	1.5	-0.1	1.1	0.6	0.5	0.4	0.7	0.6	1.3	1.2	0.4	0.6	-0.6	0.4	-0.4
Tanning	0.3	4.2	10.1	-2.3	-2.1	-2.0	-2.2	0.1	0.2	-1.1	-2.7	-2.7	-2.1	-2.2	-1.9	-3.2	-2.3	-1.5	-2.4	0.7	-1.5	-2.6
Average weekly spirits intake	0.3	0.4	1.5	0.7	0.4	1.2	0.6	0.5	1.1	-0.5	0.2	0.2	0.5	0.4	0.8	0.2	-0.4	0.1	0.3	-0.9	0.8	-1.0
Relative age of first facial hair	0.3	0.7	1.6	-1.2	-0.9	-0.3	-0.9	-0.6	-0.6	-1.3	-0.1	-0.3	-0.9	-0.9	-1.1	-0.7	-1.0	-0.7	-1.1	0.6	0.1	-0.3
High blood pressure	0.3	0.9	3.3	-0.3	-0.2	-0.5	-0.1	-1.4	0.1	-1.5	1.2	-1.0	-0.2	-0.4	0.7	1.1	-1.0	-0.3	-0.2	-1.4	1.8	-0.9
Hayfever, allergic rhinitis or eczema	0.3	0.6	3.8	0.1	1.0	-0.3	0.9	1.1	1.9	1.2	-0.3	0.2	1.0	0.8	0.5	0.0	0.8	0.5	0.4	-0.1	-0.6	0.4
Medication: Atenolol	0.3	0.3	2.1	-0.1	-0.5	-0.2	-0.3	-0.5	0.2	-1.0	-0.7	-0.4	-0.4	-0.0	0.2	-0.8	-0.3	0.6	-0.2	1.5	-0.6	-0.3
Medication: Levothyroxine sodium	0.3	0.5	2.4	1.0	0.4	-0.0	0.4	-0.3	-0.2	-0.0	1.5	0.7	0.4	0.4	0.6	1.6	0.2	0.4	0.7	-0.8	0.9	0.1
Past tobacco smoking	0.3	0.5	2.9	0.2	0.3	0.3	0.4	-1.0	1.7	-0.5	0.4	-0.2	0.4	0.6	0.6	1.5	0.4	0.1	0.2	-1.0	-0.0	0.5
Hearing difficulty/problems with background noise	0.3	0.5	1.7	-0.4	-1.0	-0.1	-1.2	-0.6	0.0	0.6	-0.1	-1.2	-1.1	-1.0	-1.3	-0.7	-0.1	-0.6	-0.7	0.3	0.1	-0.6
Had other major operations	0.3	0.4	1.2	0.6	-0.5	-0.9	-0.5	0.4	-1.0	-1.0	0.5	-0.0	-0.5	-0.6	-0.3	-1.1	-0.7	-0.2	-0.2	-0.5	0.5	-0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	3.9	0.4	0.5	-1.0	0.4	0.1	2.0	0.3	0.0	0.1	0.4	0.5	0.5	0.3	0.9	0.2	0.5	0.0	0.2	0.3
Diabetes (self-reported)	0.3	0.5	1.5	-1.1	-0.4	-0.4	-0.4	0.4	-1.0	1.2	-0.7	-0.8	-0.4	-0.3	-0.4	-1.1	-0.5	0.1	-0.6	1.2	-0.0	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	1.3	-0.9	-0.7	-0.0	-0.5	0.9	0.2	0.3	-0.6	-0.6	-0.6	-0.4	-0.1	0.2	-0.6	-0.6	-0.4	-0.8	0.7	-1.2
Asthma	0.3	0.6	2.5	0.5	0.2	1.3	0.3	1.2	1.2	-0.3	-1.6	0.1	0.2	0.2	0.0	-0.2	0.9	0.1	0.0	-0.5	-1.1	-0.9
Pulse wave reflection index	0.3	0.3	1.0	-0.3	0.6	-0.7	0.5	-0.6	0.1	-0.5	0.9	0.5	0.6	0.3	0.4	0.3	-1.0	-0.7	0.2	-0.5	-0.0	0.9
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.6	-0.5	-0.5	0.1	-0.5	-0.9	-1.2	-1.2	0.1	0.1	-0.5	-0.6	-0.9	-0.7	-0.4	-0.1	-0.4	0.1	-0.1	-0.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.5	1.5	0.8	-0.3	-0.4	-0.2	1.2	-1.1	0.8	-0.7	0.2	-0.3	-0.2	0.5	-1.1	0.2	0.2	0.2	1.0	-0.9	-0.4
Medication: Paracetamol	0.3	0.5	3.0	-0.4	-0.2	0.8	-0.3	-0.4	-1.7	-0.3	-0.6	0.4	-0.2	-0.3	-0.2	-1.6	-0.7	0.4	-0.1	0.5	-0.7	-0.0
Gout (self-reported)	0.3	0.4	1.6	0.7	0.6	-0.3	0.6	-1.3	1.1	0.4	-0.1	0.5	0.6	0.6	0.6	0.6	0.5	0.9	0.5	0.3	0.1	-0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.8	1.1	0.5	-0.2	0.6	0.3	0.3	0.1	1.3	0.4	0.5	0.7	0.7	1.7	0.6	0.2	0.7	-1.3	0.8	0.1
Number of children fathered	0.3	0.3	2.2	-0.3	0.5	1.5	0.6	0.4	0.3	0.6	-0.2	-0.0	0.5	0.4	0.8	0.2	-0.3	-0.5	0.2	0.5	-0.6	0.6
Eye problems/disorders: None of the above	0.3	0.3	1.8	0.5	-0.0	1.3	0.1	0.3	-1.1	-0.5	0.4	0.9	0.0	-0.2	0.6	0.6	-0.4	0.2	0.3	0.3	-0.2	-0.6
Medication: Ibuprofen	0.3	0.3	1.6	-1.3	-0.3	0.7	-0.1	-1.1	0.4	-0.8	0.5	0.2	-0.3	-0.1	-0.2	-0.7	-0.7	-0.1	-0.3	-0.5	-0.0	0.3
Medication: Omeprazole	0.3	0.4	1.2	0.1	-0.4	-0.3	-0.2	0.7	1.0	-1.1	0.0	-0.7	-0.4	-0.3	0.6	1.0	-0.1	-0.7	-0.1	-0.5	0.9	-0.3
Leg fat mass (right)	0.3	1.0	4.5	0.5	0.4	0.2	0.3	0.8	-2.1	1.2	-0.3	1.2	0.3	0.0	0.5	-1.8	0.1	0.3	0.4	2.1	-1.7	0.3
Alcohol intake frequency.	0.3	0.8	2.6	-0.4	-0.8	-1.5	-0.8	1.1	-0.3	-1.6	0.6	-0.7	-0.8	-1.0	-0.8	-0.3	-0.9	-1.1	-0.5	-1.2	0.6	-0.2
Had major operations	0.3	0.3	2.4	-0.2	0.3	-0.5	0.2	-0.5	0.6	0.4	1.6	0.0	0.3	0.2	0.1	0.2	-0.3	-0.6	-0.0	-0.3	0.9	0.9
Friendships satisfaction	0.3	0.3	1.6	-0.5	-0.3	-0.5	-0.3	-0.2	-0.2	-0.5	-0.4	-0.6	-0.3	-0.3	-0.4	-0.9	-0.2	0.2	-0.2	1.2	-1.1	0.5
Asthma (self-reported)	0.3	0.6	3.7	0.4	0.2	0.9	0.3	1.2	1.3	-0.3	-1.9	-0.0	0.3	0.2	0.0	-0.4	0.9	0.1	-0.1	-0.3	-1.4	-1.1
Medication: Aspirin	0.3	0.5	1.4	-0.9	-0.7	1.0	-0.6	-0.8	0.5	-0.6	-0.8	-1.2	-0.7	-0.5	0.1	-0.8	-0.4	0.2	-0.6	0.6	0.3	-0.4
Arm fat mass (left)	0.3	1.4	4.6	0.9	0.8	1.1	0.7	1.9	-0.7	1.9	-0.6	1.2	0.7	0.5	0.9	-1.9	0.8	0.7	0.8	2.1	-1.9	0.3
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.5	-0.3	-0.5	-0.2	-0.6	0.6	-1.2	1.4	-1.2	0.5	-0.5	-0.3	-1.5	-1.1	0.5	-0.3	-0.5	1.1	-1.6	0.5
Leg fat mass (left)	0.3	1.0	4.7	0.5	0.4	0.3	0.3	0.8	-2.2	1.3	-0.2	1.2	0.4	0.1	0.4	-1.7	0.2	0.2	0.5	2.0	-1.6	0.4
Ulcerative Colitis (UC)	0.2	0.3	0.9	-0.9	-0.7	-0.1	-0.6	-0.4	-0.4	-0.1	-0.3	-0.9	-0.6	-0.4	-0.7	-0.2	-0.5	-0.8	-0.7	-0.9	0.5	0.3
Coronary Artery Disease (CAD)	0.2	0.3	2.0	0.0	0.2	-0.4	0.1	0.2	0.4	-0.1	1.1	0.2	0.2	0.1	-0.1	0.5	0.3	-0.2	0.2	-1.4	0.8	0.5
Triglycerides	0.2	0.3	1.4	0.2	0.5	0.6	0.5	-0.8	0.0	-0.0	0.6	0.5	0.4	0.5	0.4	-0.0	0.2	0.1	0.6	-1.2	0.2	0.6
Lung FEV1/FVC ratio	0.2	1.2	5.9	-0.5	-0.7	-2.4	-0.5	-2.0	-1.1	-0.2	-0.9	-0.3	-0.7	-0.5	-0.2	-1.4	-0.5	-0.2	-0.6	1.9	-1.4	-0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.0	0.2	0.1	0.0	0.1	0.9	1.0	0.9	-0.1	-0.1	0.1	0.4	0.2	-0.3	0.6	0.2	0.2	-1.0	0.4	0.1
Trunk fat percentage	0.2	0.9	3.8	-0.1	-0.7	-0.3	-0.8	1.1	-1.8	0.4	-0.5	-0.0	-0.8	-1.1	-0.3	-1.9	-0.8	-0.4	-0.6	1.4	-0.8	-1.1
Maternal smoking around birth	0.2	0.3	2.0	-0.2	0.1	-0.6	0.0	-0.2	-0.2	1.3	-0.2	-0.1	0.1	0.0	-0.3	-1.4	-0.2	0.4	-0.1	0.1	-0.5	0.6
Taking other prescription medications	0.2	0.3	1.0	-0.0	-0.6	0.4	-0.6	0.0	0.1	-0.3	-0.8	-0.6	-0.6	-0.6	-0.4	-1.0	-0.2	0.1	-0.7	0.6	-0.8	-1.0
Age when periods started (menarche)	0.2	0.5	2.2	-0.4	-0.3	-1.3	-0.4	0.3	0.1	-0.1	0.6	-0.2	-0.3	0.1	-0.7	0.9	-0.1	-1.5	-0.4	-1.2	0.9	0.0
Multivitamins +/- minerals	0.2	0.2	1.2	-0.1	-0.3	-1.1	-0.3	0.6	0.0	-0.3	-0.4	-0.7	-0.3	-0.2	-0.2	-0.7	-0.3	-0.2	-0.3	0.9	-0.5	-0.2
High blood pressure (mother)	0.2	0.3	1.6	-0.3	-0.7	-0.6	-0.6	0.2	-0.1	0.1	-1.0	-0.8	-0.7	-0.5	-0.2	-0.2	-0.0	0.1	-0.6	0.7	-0.4	-1.2
Alcohol usually taken with meals	0.2	0.4	1.6	-0.1	0.2	-0.9	0.1	1.3	0.9	1.0	-0.8	-0.7	0.2	0.2	-0.6	-0.0	0.5	0.0	-0.3	0.4	-0.5	-0.2
Medication: Simvastatin	0.2	0.4	1.2	-1.1	-0.6	0.2	-0.5	0.1	-0.3	-0.2	-0.4	-0.9	-0.6	-0.5	0.1	-0.6	-0.7	-1.0	-0.6	0.6	0.5	-0.7
Arm fat percentage (right)	0.2	0.7	1.6	0.1	-0.7	-0.2	-0.7	1.3	-0.8	-0.8	0.9	-0.2	-0.8	-1.1	0.2	-1.2	-1.3	-0.8	-0.3	1.1	0.0	-0.8
Hip circumference	0.2	0.9	4.1	-0.9	0.2	0.6	-0.1	0.3	-1.6	1.0	-1.2	-0.0	0.1	-0.3	-0.9	-1.9	-0.2	-0.8	-0.5	1.4	-2.0	-0.1
Mouth/teeth dental problems: Dentures	0.2	0.4	1.6	-0.1	-0.4	-0.5	-0.4	0.4	-0.6	0.4	-1.3	-0.4	-0.4	-0.5	-0.7	-1.2	0.1	0.1	-0.2	0.8	-0.8	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.1	-1.0	-0.5	0.0	-0.3	-0.8	0.3	-0.7	0.4	-0.1	-0.4	-0.2	-0.4	-1.0	-0.8	0.5	-0.2	-0.3	-0.3	0.2
Arm fat mass (right)	0.2	1.0	3.6	0.7	0.5	0.9	0.5	1.5	-0.8	1.5	-0.3	1.0	0.5	0.3	0.7	-1.6	0.6	0.5	0.7	1.9	-1.6	0.3
Breastfed as a baby	0.2	0.3	1.2	0.5	-0.1	-0.3	-0.1	0.9	-0.7	0.6	-0.4	0.4	-0.2	0.0	0.4	0.1	0.6	0.8	0.2	1.1	-0.1	-0.3
Peak expiratory flow (PEF)	0.2	0.5	2.2	-0.1	0.4	1.5	0.4	-1.1	-1.0	0.4	1.1	0.8	0.4	0.5	0.3	0.8	-0.0	-0.5	0.5	-0.7	0.1	1.1
Glaucoma (self-reported)	0.2	0.2	1.2	-0.6	-0.3	-1.0	-0.3	0.2	0.6	-0.0	-0.3	-1.1	-0.3	-0.3	-0.2	-0.6	-0.3	-0.2	-0.4	0.2	0.4	0.1
Body fat percentage	0.2	0.9	3.5	-0.2	-0.8	-0.6	-0.9	0.9	-1.9	-0.4	0.1	-0.1	-0.9	-1.2	-0.1	-1.8	-1.2	-0.7	-0.6	1.4	-0.5	-1.1
Migraine (self-reported)	0.2	0.2	0.9	0.4	-0.3	-0.2	-0.2	0.1	-0.9	0.0	0.8	-0.7	-0.3	-0.2	-0.2	0.7	0.2	-0.6	-0.1	-0.6	0.8	0.2
Heart disease (mother)	0.2	0.2	1.5	-0.1	0.2	-0.1	0.3	-1.2	0.4	-0.6	-0.1	0.1	0.3	0.2	0.2	0.3	0.0	0.8	0.1	0.7	-0.1	0.6
Medication: Aspirin	0.2	0.3	1.1	-0.7	-0.5	0.9	-0.4	-0.8	0.5	-0.8	-0.2	-1.1	-0.5	-0.4	0.2	-0.4	-0.6	0.2	-0.4	0.1	0.6	0.0
Knee pain experienced in last month	0.2	0.3	1.7	-1.0	-0.6	-0.1	-0.6	-0.2	-0.1	-0.5	-0.1	-0.1	-0.7	-0.7	0.1	-1.3	-0.8	-0.2	-0.5	0.3	-0.5	0.1
Arm fat percentage (left)	0.2	0.6	2.5	0.1	-0.7	-0.2	-0.7	1.6	-0.5	-0.6	0.6	-0.1	-0.8	-1.1	0.3	-1.3	-1.1	-0.6	-0.3	1.2	-0.2	-0.9
Commuting to job workplace: Walk	0.2	0.2	1.7	0.1	0.1	0.2	0.0	1.1	-0.7	1.3	-0.0	0.5	0.1	-0.0	-0.0	-0.5	0.4	-0.3	0.2	-0.1	0.4	0.3
Eye problems/disorders: Cataract	0.2	0.2	1.0	-0.3	0.4	-0.8	0.2	-0.2	0.4	0.4	-0.5	-0.5	0.3	0.2	-0.1	-1.0	0.0	0.2	-0.1	0.5	-0.7	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	1.6	0.2	0.1	0.4	0.3	-0.8	-0.6	-1.1	-0.1	0.7	0.0	-0.0	1.3	-0.2	-0.1	0.3	0.5	0.0	-0.0	0.1
Osteoporosis (self-reported)	0.2	0.3	1.4	-0.2	-0.6	-0.6	-0.6	-0.5	-1.2	0.1	-0.6	-0.1	-0.6	-0.5	-0.3	-0.6	-0.1	-0.2	-0.6	-0.3	0.2	-1.0
Illnesses of father: None of the above (group 1)	0.2	0.2	0.7	0.1	-0.3	-0.5	-0.3	-0.6	0.5	0.2	-0.8	-0.6	-0.3	-0.1	-0.2	-0.3	0.5	0.8	-0.0	0.3	-0.3	-0.4
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.7	0.2	0.1	-0.3	0.1	0.2	0.3	-0.0	-0.5	0.6	0.1	-0.1	0.1	-1.3	-0.3	0.1	0.1	1.0	-0.7	-0.8
Eye problems/disorders: Glaucoma	0.2	0.2	0.9	-0.7	-0.0	-0.8	-0.1	-0.5	0.9	-0.1	0.0	-0.8	-0.0	0.0	-0.4	-0.3	-0.2	-0.2	-0.3	-0.1	0.4	0.3
High cholesterol (Self-reported)	0.2	0.4	1.3	1.0	0.6	0.1	0.8	-0.1	-0.1	1.1	0.6	0.3	0.6	0.9	1.1	0.6	0.7	0.5	0.8	0.2	0.4	0.7
Medication: Lisinopril	0.2	0.3	1.7	0.4	-0.3	-1.1	-0.3	0.7	-0.7	0.9	-0.1	-0.1	-0.3	-0.3	0.3	-0.6	-0.1	0.1	-0.2	1.3	-0.3	-0.4
Average weekly beer plus cider intake	0.2	0.3	1.6	0.2	-0.2	0.4	-0.3	0.4	0.6	-0.6	-1.1	0.0	-0.3	-0.4	-0.2	-0.1	0.6	0.7	-0.2	-0.1	-1.3	-1.0
Irritability	0.2	0.3	1.8	-0.9	-0.0	1.4	-0.2	-0.8	0.2	-0.1	-0.1	-0.1	-0.1	0.3	-0.6	-0.3	-0.5	-0.2	-0.5	-1.0	0.1	-0.9
Risk taking	0.2	0.4	2.6	0.5	0.1	-0.7	0.2	1.6	0.5	0.7	0.7	-0.1	0.1	0.0	0.5	0.2	0.4	-0.3	0.4	-1.1	0.4	0.4
Irritable Bowel Disease (IBD)	0.1	0.3	1.6	-0.1	0.1	0.1	0.3	0.9	0.4	0.9	-1.1	0.1	0.3	0.5	-0.1	-0.7	0.7	0.4	0.0	0.3	-1.2	0.4
Major Depression (MDD)	0.1	0.1	0.4	0.1	0.4	-0.0	0.3	-0.4	0.7	0.1	-0.2	-0.1	0.4	0.5	0.3	-0.0	0.6	0.5	0.2	-0.2	0.2	0.6
HDL Cholesterol	0.1	0.2	0.7	-0.2	-0.4	0.5	-0.5	0.5	-0.2	0.8	0.3	-0.8	-0.4	-0.3	-0.8	0.3	-0.5	-0.4	-0.5	0.2	0.4	-0.6
Blood Eosinophil Count	0.1	0.5	1.4	1.0	0.6	-0.3	0.5	-0.1	1.1	0.3	-0.4	0.8	0.5	0.6	0.4	-0.5	1.2	0.9	0.5	1.0	-0.7	-0.2
Blood Platelet Count	0.1	1.2	5.8	-0.1	-0.5	-0.9	-0.3	-0.7	-0.1	-0.7	2.1	-0.2	-0.5	-0.2	-0.2	2.0	-0.4	-1.1	-0.2	-2.3	2.4	0.4
Blood White Count	0.1	0.4	2.5	0.5	-0.3	-0.5	-0.4	-0.0	0.4	0.4	-1.6	-0.9	-0.3	-0.4	-0.9	0.2	0.5	0.2	-0.5	0.1	-0.9	-0.9
BMI	0.1	0.8	3.2	1.0	0.5	1.4	0.7	1.6	-0.4	0.6	1.0	1.1	0.5	0.5	1.8	-0.7	0.4	0.4	1.1	1.1	-0.1	0.3
Cardiovascular Disease	0.1	0.2	0.8	0.3	-0.1	-0.8	0.0	-0.9	0.3	-0.4	0.6	-0.6	-0.2	-0.1	0.5	0.4	-0.2	0.7	0.0	-0.4	0.6	-0.7
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	1.1	0.5	0.2	-0.3	0.2	0.4	1.0	-0.4	-0.2	-0.1	0.2	0.1	0.2	0.6	0.9	0.5	0.1	-0.6	0.1	-0.1
Qualifications: CSEs or equivalent	0.1	0.1	0.7	-0.1	0.3	-0.8	0.1	-0.6	-0.2	0.3	0.3	0.6	0.2	0.1	0.3	-0.0	0.2	0.5	0.3	-0.3	0.5	0.3
Body mass index (BMI)	0.1	0.5	2.3	-0.0	-0.4	-0.1	-0.4	1.0	-0.8	-0.2	0.5	0.1	-0.5	-0.7	0.4	-1.4	-0.9	-0.4	-0.1	1.5	-0.6	-0.3
Had menopause	0.1	0.2	1.0	0.4	0.2	0.4	0.3	-0.1	-0.3	0.0	0.5	-0.0	0.2	0.4	0.5	1.0	0.3	0.0	0.4	-0.1	0.6	0.3
Financial difficulties in last 2 years	0.1	0.1	0.8	-0.4	-0.2	-0.9	-0.2	0.1	0.1	0.6	-0.1	-0.1	-0.3	-0.1	0.0	0.0	0.1	-0.3	-0.2	-0.6	-0.2	0.0
Hair/balding pattern: Pattern 4	0.1	0.2	1.4	-0.1	-0.3	-0.1	-0.2	0.2	-0.8	-0.4	1.2	0.5	-0.3	-0.4	0.1	0.4	-0.5	-0.3	0.2	-0.5	0.8	0.4
Emphysema/chronic bronchitis	0.1	0.1	0.7	0.3	0.0	-0.2	0.0	0.3	0.4	0.1	-0.3	0.4	0.0	-0.1	0.3	0.0	0.3	0.2	0.2	-0.8	-0.2	0.4
Medication for pain relief, constipation, heartburn	0.1	0.2	1.2	-0.1	0.2	-1.0	-0.0	0.0	-0.3	1.1	-0.1	0.2	0.1	0.0	-0.4	0.5	0.3	-0.5	-0.1	0.7	-0.1	-0.2
Medication: Blood pressure	0.1	0.3	1.7	0.3	0.6	-0.0	0.6	0.6	0.5	-0.3	0.6	-0.5	0.5	0.4	1.3	0.1	-0.0	0.4	0.4	0.3	0.5	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.5	0.6	-0.3	0.6	-0.2	0.5	-0.7	-0.4	0.2	-0.2	-0.3	-0.3	0.5	-0.3	0.0	-0.3	0.4	-0.1	0.5	-0.3
Long-standing illness, disability or infirmity	0.1	0.1	0.9	-0.1	0.0	0.9	0.0	-0.1	0.7	0.1	-0.2	-0.2	0.0	-0.0	0.1	-0.6	0.2	0.4	-0.0	-0.3	0.0	-0.3
Qualifications: nursing, teaching	0.1	0.2	0.7	-0.3	0.0	0.1	-0.1	-0.4	0.2	-0.6	-0.9	-0.3	-0.0	-0.1	-0.4	0.4	-0.1	-0.4	-0.5	0.3	-0.8	-0.1
Number of self-reported non-cancer illnesses	0.1	0.2	1.1	0.1	-0.2	-0.2	-0.1	0.8	0.4	-0.2	-0.6	-0.6	-0.3	-0.3	0.7	-0.3	0.1	0.1	-0.2	-0.6	0.2	-1.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.2	0.7	0.5	-0.3	0.9	-0.3	0.3	-0.7	-0.7	0.2	0.4	-0.3	-0.6	0.3	-0.0	0.1	0.4	0.4	0.3	-0.0	0.0
Hair Pigment	0.0	1.0	2.6	0.7	0.5	0.9	0.8	1.5	1.0	1.4	-0.7	0.9	0.6	0.9	1.1	0.5	1.2	1.6	0.9	1.2	-1.0	0.2

Hub : Genes

BCKDHB

Models

Trait associations