TWAS
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Usage
Models
Genes
Traits
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Traits
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Whole body fat-free mass
:
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chr7:49,817,957-51,215,365
Best TWAS P=2.59e-09 · Best GWAS P=2.23e-13 conditioned to 5.59e-10
49.8M
50M
50.2M
50.4M
50.6M
50.8M
51M
51.2M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Small Intestine Terminal Ileum
FIGNL1
0.21
0.23
lasso
4
0.22
1.3e-05
-6.5
-6.0
2.6e-09
-0.21
0.21
0.25
TRUE
2
The Cancer Genome Atlas
Stomach Adenocarcinoma
FIGNL1
0.05
0.00
blup
68
0.01
5.4e-02
-6.7
-5.3
1.2e-07
-0.08
0.00
0.76
FALSE