Best TWAS P=1.57e-11 · Best GWAS P=4.7e-11 conditioned to 0.389
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Adenocarcinoma | PARP12 | 0.02 | 0.01 | blup | 68 | 0.01 | 2.4e-02 | 6.4 | -6.7 | 2.7e-11 | -0.88 | 0.01 | 0.91 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PARP12 | 0.06 | 0.04 | lasso | 2 | 0.04 | 1.3e-04 | 6.3 | 6.1 | 1.4e-09 | 0.93 | 0.01 | 0.97 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | PARP12 | 0.14 | 0.11 | enet | 10 | 0.12 | 9.4e-12 | 6.6 | -6.7 | 1.6e-11 | -0.93 | 0.00 | 1.00 | TRUE |