TWAS
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Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
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chr7:139,475,320-140,010,108
Best TWAS P=1.57e-11 · Best GWAS P=4.7e-11 conditioned to 0.389
139.5M
139.6M
139.7M
139.8M
139.9M
140M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
PARP12
0.14
0.11
enet
10
0.12
9.4e-12
6.6
-6.7
1.6e-11
-0.93
0.00
1.00
TRUE
1
The Cancer Genome Atlas
Lung Adenocarcinoma
PARP12
0.02
0.01
blup
68
0.01
2.4e-02
6.4
-6.7
2.7e-11
-0.88
0.01
0.91
FALSE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
PARP12
0.06
0.04
lasso
2
0.04
1.3e-04
6.3
6.1
1.4e-09
0.93
0.01
0.97
FALSE